ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Patient Outcomes After Heart and Double Lung Transplant from a Single High-Volume Center

    R. P. Brumer1, A. Goodarzi2, R. Chihara1

    1Department of Surgery, Houston Methodist Hospital, Houston, TX, 2J.C. Walter Jr. Transplant Center, Houston Methodist Hospital, Houston, TX

    *Purpose: Combined heart and double-lung transplant (OHT/DLT) is a relatively uncommon procedure, and patient outcomes after undergoing OHT/DLT are therefore not as well understood as…
  • 2022 American Transplant Congress

    Circulating Antibodies in CMV Viremia in Kidney Transplantation

    T. Sigdel1, P. Velpurisiva1, V. Dharnidharka2, M. M. Sarwal1

    1UCSF, San Francisco, CA, 2Washington University in St. Louis, Saint Louis, MO

    *Purpose: Role of circulating antibodies (Abs) in graft injury outcomes of kidney transplant is reported by us and others. Cytomegalovirus (CMV) is known to contribute…
  • 2022 American Transplant Congress

    Impact of Respiratory Viral Panel Testing on Clinical Decision-Making Among Lung Transplant Recipients Based on Extent of Immunosuppression

    A. C. Vostal1, A. Lynen2, S. Chintalapati1, M. Uehling1, K. Prakash2, A. Shishido1, J. Baghdadi2

    1University of Maryland Medical Center, Baltimore, MD, 2University of Maryland School of Medicine, Baltimore, MD

    *Purpose: Lung transplant recipients (LTRs) are at high risk for complications from viral respiratory infection, including chronic allograft dysfunction. Thus, multiplex molecular testing for respiratory…
  • 2022 American Transplant Congress

    Direct Central Ambulatory Venoarterial Extracorporeal Membrane Oxygenation and Double Lung Transplantation without Graft Reduction with Extreme Mediastinal Shift

    A. Gorton1, S. Keshavamurthy2

    1Cardiothoracic Surgery, University of Kentucky, Lexington, KY, 2University of Kentucky, Lexington, KY

    *Purpose: Double Lung transplantation in the presence of extreme mediastinal shift can be technically challenging due to donor sizing and recipient factors.*Methods: We present the…
  • 2022 American Transplant Congress

    Years Of Life Gained Through Organ Transplantation From Donors Deceased From Drug Overdose

    A. M. Hébert, A. L. Hill

    Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD

    *Purpose: The worsening opioid crisis in the United States has increased the availability of organs from donors who died of drug overdoses. The goal of…
  • 2022 American Transplant Congress

    Marginal Zone Phenotype B Cells Are Required for Formation of Donor-Specific IgG After Allogeneic Sensitization

    M. A. Kallarakal, G. Cohen, S. M. Krummey

    Department of Pathology, Johns Hopkins University, Baltimore, MD

    *Purpose: The formation of allogeneic antibody directed against non-self MHC, termed donor-specific antibody (DSA), is a significant barrier to successful transplant outcomes. Pre-formed DSA limits…
  • 2022 American Transplant Congress

    Equivalence of Pediatric Paper and Electronic-Based Patient-Reported Outcome Measures: Findings from a Systematic Review

    S. Kortbeek1, A. Pawaria2, V. L. Ng1

    1Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, 2Pediatric Hepatology, Gastroenterology and Liver Transplant, Global Hospitals, Mumbai, India

    *Purpose: Integration of patient reported outcome measures (PROMs) in routine clinical care reduces utilisation of health care services and improves patient outcomes. Electronic versions of…
  • 2022 American Transplant Congress

    Adoptive Transfer OfMesenchymal Stem Cells Activates Hedgehog/SMO/Gli1 Signaling And Inhibits STING-mediated Innate Immune Response In Liver Transplant Inflammatory Injury

    D. Xu1, X. Qu1, Y. Tian1, M. Sheng1, Y. Lin1, Y. Zhan1, F. M. Kaldas1, R. W. Busuttil1, D. G. Farmer1, J. W. Kupiec-Weglinski1, Q. Xia2, B. Ke1

    1Surgery, Dumont - UCLA Transplant Ctr, Los Angeles, CA, 2Liver Surgery, Shanghai Jiaotong University School of Medicine, Shanghai, China

    *Purpose: The stimulator of interferon genes (STING) pathway has been recognized as a crucial signaling cascade of the innate immune system. Activation of the Hedgehog…
  • 2022 American Transplant Congress

    Deep-Learning Based Pathological Assessment of Frozen Procurement Kidney Biopsies

    Z. Yi1, C. Xi1, M. Menon2, P. Cravedi1, B. Murphy1, S. Ward1, F. Salem1, W. Zhang1

    1Icahn School of Medicine at Mount Sinai, New York, NY, 2Yale University School of Medicine, New York, NY

    *Purpose: Organ shortage in kidney transplantation is a major issue for ESKD individuals on the waiting list. Sclerotic glomeruli or interstitial fibrosis on procurement donor…
  • 2022 American Transplant Congress

    The Unique Course of dd-cfDNA After Lung Transplant

    D. Levine1, C. Giner1, C. Pham2, R. Woodward3, A. Roux4

    1University of Texas Health System San Antonio, San Antonio, TX, 2CareDX, South San Francisco, CA, 3CareDx, South San Francisco, CA, 4Pneumology, Adult CF Center and Lung Transplantation Department, Foch Hospital, Suresnes, France

    *Purpose: The time necessary for dd-cfDNA to reach baseline levels following transplantation has been reported in kidney, heart, and liver as 14-21 days. We explored…
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