2013 American Transplant Congress
CD8+ Cytotoxic T Cells Inhibit Alloantibody Production by Killing Alloprimed B Cells
Introduction- While it is well known that CD4+ T cells and B cells collaborate for antibody (Ab) production, our group has recently reported a novel…2013 American Transplant Congress
Total Plasma Exchange Does Not Improve Allograft Outcome in Deceased Donor Liver Transplant When Performed for Allograft Dysfunction and Positive Cross-Match
BACKGROUND: Although total plasma exchange (TPE) has been used in ABO incompatibility, and in cases of allograft dysfunction particularly in the presence of a positive…2013 American Transplant Congress
Novel Role of PI3K Delta Inhibition in Both T and B Cell Activation in Alloimmunity, The
Renal, Brigham and Women's Hospita, Boston, MA
The PI3K family of dual lipid and protein kinases phosphorylates Akt into pAkt, triggering kinase cascades downstream that play a central role in cell proliferation…2013 American Transplant Congress
Messenger RNA Levels in Non-Invasive Samples Can Potentially Stratify Risk of Rejection in Renal Transplant Recipients
Identification of molecular biomarkers in blood and urine samples has the potential to revolutionize post transplantation management. Such biomarkers could help risk stratify patients and…2013 American Transplant Congress
Incorporating a Vascularized Composite Allograft Transplant Program into a Transplant Center
Transplant Surgery, Massachusetts General Hospital, Boston, MA
Vascularized Composite Allograft (VCA) transplant programs are currently not regulated by the Organ Procurement and Transplantation Network (OPTN) or by the Centers for Medicare and…2013 American Transplant Congress
Outcomes of 23 Shipped Paired Donor Kidneys in an Integrated KPD Program
Introduction: Kidney paired donation (KPD) programs provide the possibility of ABO compatible or negative crossmatch transplants for recipients whose original donor was incompatible. The goal…2013 American Transplant Congress
Blocking CD47 Reduces Ischemia Reperfusion Injury and Improves Kidney Transplantation Outcomes
Ischemia reperfusion injury (IRI) contributes to delayed graft function, inflammation and graft loss. Many components of IRI are ameliorated by nitric oxide (NO) signaling. The…2013 American Transplant Congress
Combination of Steroids and Methotrexate with Costimulation Blockade Prolongs Renal Allograft Survival, The
Emory Transplant Center, Atlanta, GA; Yerkes National Primate Research Center, Atlanta, GA
Background: While costimulation blockade (CoB) has improved renal allograft function in clinical studies, this comes at the cost of increased rates of early rejection. These…2013 American Transplant Congress
125 Cases of Duodenoduodenostomy in Pancreas Transplantation: A Single-Center Experience of an Alternative Enteric Drainage
Department of Surgery, Ruhr-University-Bochum, Bochum, Northrhine-Westfalia, Germany
Backround: Different technical procedures have been developed successfully to perform pancreas transplantation (PT) with regard to exocrine drainage. Retroperitoneal graft placement behind the right colon…2013 American Transplant Congress
Racial Disparities in GRAFT SURVIVAL in the Elderly KIDNEY Transplant Patients
Over the past decade, the amount of elderly patients living with CKD and on dialysis has increased in part due to the survival benefit of…
American Transplant Congress abstracts