2013 American Transplant Congress
Antibody-Mediated Injury Is the Major Cause of Late Kidney Allograft Failure
DeKAF is NIH-funded multicenter observational study of late kidney graft failure with over 4500 recs enrolled from 2006-10. The Cross-Sectional cohort (CS, N=559) includes recs…2013 American Transplant Congress
Kidney Intragraft DSA as Determinant of Antibody-Mediated Lesions and Poor Graft Outcome
Allograft pathology, antibody-tissue interaction as demonstrated by C4d deposition, and serologic evidence of donor-specific antibodies (DSA) are the cardinal diagnostic features of antibody-mediated lesions (AML)…2013 American Transplant Congress
Interactive Web-Based Patient Portal for the Evaluation of Potential Kidney Transplant Recipients
Kidney Transplant Service, UCSF, San Francisco, CA
Introduction: UCSF implemented newly available information technology to increase access to patients, improve communication, and expedite patient work-up. Using a validated(1-2) web-based software platform (BREEZE…2013 American Transplant Congress
RBC Transfusions Are Associated with HLA Allosensitization in Patients Awaiting Kidney Transplantation
Introduction: HLA sensitization remains a major barrier to successful kidney transplantation resulting in prolonged wait times, lower transplant rates, and decreased graft survival. This study…2013 American Transplant Congress
Long Term Survival of PEGylated Murine Allogenic Islets Using Short Course Immunomodulation
Islet transplantation is a promising therapy for Type 1 diabetes; however, inflammatory and immune host responses lead to islet dysfunction and destruction. Cell surface PEGylation…2013 American Transplant Congress
Effects of Human Alpha-1-Antitrypsin (hAAT) Therapy in a Murine Model of Bilateral Kidney Ischemia-Reperfusion Injury
AIM: Several lines of evidence have demonstrated the anti-inflammatory and cytoprotective effects of alpha-1-Antitrypsin (AAT), the major serum serine-protease inhibitor. The aim of the present…2013 American Transplant Congress
Factors Associated with Renal Dysfunction at 12 Months Following Liver Transplantation
Introduction: Renal dysfunction (RD) before and after liver transplantation (LTx) is a significant predictor of graft failure (GF). We investigated the association of donor and…2013 American Transplant Congress
Use of Software Imaging To Detect Sarcopenia in Lung Transplant Candidates
Background:Abnormal body mass index (BMI) (both <19 and >30 kg/m2) has been associated with worse outcomes in lung transplantation. However, this measurement cannot assess risks…2013 American Transplant Congress
Normothermic In Vivo Graft Perfusion Decreases the Risk of Hepatocellular Carcinoma Recurrence in a Donation-after-Cardiac-Death (DCD) Rat Liver Transplantation Model
Background: Liver transplantation from DCD donors is associated to ischemia/reperfusion (IR) lesions, which may increase the risk of post-transplant hepatocellular carcinoma (HCC) recurrence. Normothermic graft…2013 American Transplant Congress
Fatigue as Reported at 12 Time Points during the First Year Post-Liver Transplant
BACKGROUND: Although liver transplantation has evolved as an effective procedure, fatigue remains a post-transplant complaint [1]. As yet, there are no published accounts of the…