2013 American Transplant Congress
Peripheral Expression of Inflammatory Proteins and miRNAs Expression at the Time of Biopsy Proven ACR and Persistence of Immune Activation Long after Clinical Resolution
The aim of this exploratory study was to determine whether inflammatory proteins and/or miRNA in serum specimens collected at the time of biopsy-proven rejection (ACR),…2013 American Transplant Congress
Influence of Steroid Maintenance on the Outcomes in Sensitized Kidney Transplant Recipients
Steroid withdrawal protocols are increasingly used in kidney transplantation. However, sensitized patients considered high immune risk are maintained on steroid by many centers. It is…2013 American Transplant Congress
Compartmentalization of Acute Versus Chronic Rejection in Cardiac Allografts
Immunology, Cleveland Clinic, Cleveland, OH
Acute rejection of cardiac allografts is characterized by interstitial infiltrates and diagnosed by endomyocardial biopsies. In contrast, chronic rejection is distinguished by vasculopathy in large…2013 American Transplant Congress
Impact of Cholecalciferol Repletion on Alloreactivity in Vitamin D-Deficient Hemodialysis Patients: A Randomized Controlled Trial
Dept of Medicine, Mount Sinai School of Medicine, NY, NY
Background: 25OH-Vit D deficiency is common in hemodialysis (HD) patients despite therapy with 1,25OH-Vit D, and is associated with increased T cell memory. The purpose…2013 American Transplant Congress
Therapeutic Dosing of Mycophenolate Mofetil (MMF) in Renal Allograft Recipients Decreases with Increasing Age
PinnacleHealth, Harrisburg, PA
Background: Measurement of 2-hour Mycophenolic Acid Area-Under-Cure (MPA AUC) has been shown to allow accurate dosing of MMF for therapeutic efficacy. While inadequate MMF administration…2013 American Transplant Congress
UNOS Regional Risk Factors for Graft Failure in Kidney Transplantation
Aim: To identify UNOS regional variations in graft failure.Methods: UNOS database of 17,273 adult recipients transplanted from 06-30-2004 to 01-01-2007. Potential risk factors of interest…2013 American Transplant Congress
Outcome of Aristolochic Acid Nephropathy after Renal Transplantation
Background: In the early 1990s, intake of slimming pills containing Aristolochic Acids (AA) led to a rapidly progressive kidney failure secondary to an interstitial renal…2013 American Transplant Congress
Human Anti-Pig Xenogeneic T-Cell Response in the Absence of HD Antigen
Surgery, Indiana University, Indianapolis, IN
Organ supply remains the primary barrier to liver transplantation. Xenotransplantation provides a potential source to meet this shortage. HD antigen is a known xenoantigen to…2013 American Transplant Congress
Endothelial Cell Reactive Antibodies: Antigenic Targets and Mechanism of Action
The initial contact point between a recipient’s immune system and a transplanted graft is the vascular endothelium. Our goal is to identify the antigenic targets…2013 American Transplant Congress
Detecting BK Virus in the Graft Identifies Positive BK Viremia Patients at High Risk of Developing BKVAN
BK virus-associated nephropathy (BKVAN) is the leading cause of infection-related graft loss in renal transplantation. The lack of sensitivity of transplant biopsy in the diagnosis…
American Transplant Congress abstracts