ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Frailty and Early Hospital Readmission after Kidney Transplantation

    M. McAdams-DeMarco, A. Law, M. Salter, J. Walston, D. Segev

    Johns Hopkins University School of Medicine, Baltimore, MD

    BACKGROUND: Early hospital readmission (EHR) after kidney transplantation (KT) is associated with increased morbidity, transplant costs, and risk of transition-of-care errors. Registry-based recipient, transplant, and…
  • 2013 American Transplant Congress

    Pregnancy Outcomes in Solid Organ Transplant Recipients with Exposure to Sirolimus

    S. Constantinescu, L. Coscia, M. Moritz, C. McGrory, C. Ramirez, V. Armenti

    Medicine, Temple University School of Medicine, Philadelphia; Surgery, Thomas Jefferson University, Philadelphia; Surgery, Lehigh Valley Health Network, Allentown, PA; National Transplantation Pregnancy Registry, Philadelphia

    The purpose of this study was to describe pregnancy outcomes with exposure to sirolimus. Data were collected by the National Transplantation Pregnancy Registry (NTPR) via…
  • 2013 American Transplant Congress

    Hanging Donors: Are We Still Skeptical about Those Lungs?

    P. Mohite, D. Saez, A. Sabashnikov, B. Zych, N. Patil, A. Moza, F. DeRobertis, T. Bahrami, M. Amrani, A. Reed, M. Carby, A. Simon

    Department of Cardiothoracic Transplantation & Mechanical Support, Royal Brompton and Harefield NHS Trust, Harefireld, Middlesex, United Kingdom

    PurposeSuicidal hanging causes compression of the neck blood vessels and the airway leading to hypoxic brain damage due to cerebral ischemia and respiratory distress. Hanging,…
  • 2013 American Transplant Congress

    Mesenchymal Stem Cell Therapy To Promote Functional Recovery in a Limb Transplant Model

    E. Fitzpatrick, M. DeHart, J. Tercero, T. Brown, S. Salgar

    Clinical Investigation, MAMC; Surgery, Madigan Army Medical Center, Tacoma, WA

    Introduction: Hand and leg transplantation (Tx) in military and civilian populations is increasingly needed to improve the quality of life of individuals. Optimizing nerve regeneration…
  • 2013 American Transplant Congress

    Undetected Lesion as a Risk Factor for Recurrence in Patients Transplanted for HCC, The

    L. Teperman, E. Cahan, A. David, B. Gelb, G. Morgan, H. Tobias

    NYU SOM, New York, NY; U of M, Ann Arbor, MI

    Background: OLT is the definitive treatment for HCC. Vascular invasion, tumor size, and proliferation are known risk factors for recurrence post-OLT. Undetected lesions <1cm are…
  • 2013 American Transplant Congress

    Children Develop De Novo Anti-HLA Antibodies (Abs) Following Kidney Transplantation at a Higher Incidence Than Adults: An Analysis of the NIH CTOT/CCTPT-02 Study

    W. Harmon, I. Guleria, D. Ikle, B. Armstrong, L. Spaneas, Y. Morrison, N. Bridges, M. Sayegh, A. Chandraker

    Boston Children's Hospital and Brigham and Women's Hospital, Harvard Medical School, Boston, MA; RHO, Chapel Hill, NC; NIAID, NIH, Bethesda, MD

    The NIH CTOT/CCTPT-02 examined the development of post transplant de novo anti-HLA Abs in unsensitized kidney transplant recipients. It is a multi-center observational study that…
  • 2013 American Transplant Congress

    IL37 Controls IL18 Induced Pro-Inflammatory Cytokine Expression by Tubular Cells and Attenuates Renal Ischemia-Reperfusion Injury

    Y. Yang, Z. Yin, S. Ma, Z. Zhang, A. Jevnikar

    Matthew Mailing Centre for Translational Transplantation Studies, London Health Sciences Centre, London, Canada; Pathology, Western University, London, Canada; Medicine, Western University, London, Canada; Biology, Western University, London, Canada

    IL37 is a newly described member of the IL-1 family,which is anti-inflammatory by its inhibition of pro-inflammatory cytokine production. While human IL37 has no murine…
  • 2013 American Transplant Congress

    Rapamycin-Induced Augmentation of the CD8 T Cell Response to a Latent Viral Infection Is Inhibited by CTLA4-Ig

    D. Pinelli, M. Wagener, M. Ford

    Emory University, Atlanta, GA

    Latent viral infections are a major concern among immunosuppressed transplant patients. Treatment with belatacept, a CTLA4-Ig fusion protein, was shown to reduce toxicity in kidney…
  • 2013 American Transplant Congress

    Epitope Matching Outperforms Traditional Antigen Matching as a Predictor of De Novo Donor Specific Antibody Development after Renal Transplantation

    C. Wiebe, D. Pochinco, T. Blydt-Hansen, I. Gibson, D. Rush, P. Nickerson

    Medicine, University of Manitoba, Winnipeg, Canada; Immunology, University of Manitoba, Winnipeg, Canada; Diagnostic Services of Manitoba, University of Manitoba, Winnipeg, Canada; Pediatric and Child Health, University of Manitoba, Winnipeg, MB, Canada; Pathology, University of Manitoba, Winnipeg, Canada

    Hypothesis:An epitope based HLA matching approach will be predictive of de novo Donor Specific Antibody (dnDSA) development after renal transplantation.Methods:315 consecutive renal transplants were performed…
  • 2013 American Transplant Congress

    Cell Necrosis and Immune Activation: Does Injury Alter Acquired Alloimmunity?

    S. Hashmi, M. Ford, C. Larsen, A. Kirk

    Emory Transplant Center, Atlanta, GA

    Adaptive immune responses are directed by specific recognition of antigen but are also driven by general contextual signs of injury. Organ transplantation provides both of…
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