2013 American Transplant Congress
Frailty and Early Hospital Readmission after Kidney Transplantation
Johns Hopkins University School of Medicine, Baltimore, MD
BACKGROUND: Early hospital readmission (EHR) after kidney transplantation (KT) is associated with increased morbidity, transplant costs, and risk of transition-of-care errors. Registry-based recipient, transplant, and…2013 American Transplant Congress
Pregnancy Outcomes in Solid Organ Transplant Recipients with Exposure to Sirolimus
The purpose of this study was to describe pregnancy outcomes with exposure to sirolimus. Data were collected by the National Transplantation Pregnancy Registry (NTPR) via…2013 American Transplant Congress
Hanging Donors: Are We Still Skeptical about Those Lungs?
PurposeSuicidal hanging causes compression of the neck blood vessels and the airway leading to hypoxic brain damage due to cerebral ischemia and respiratory distress. Hanging,…2013 American Transplant Congress
Mesenchymal Stem Cell Therapy To Promote Functional Recovery in a Limb Transplant Model
Clinical Investigation, MAMC; Surgery, Madigan Army Medical Center, Tacoma, WA
Introduction: Hand and leg transplantation (Tx) in military and civilian populations is increasingly needed to improve the quality of life of individuals. Optimizing nerve regeneration…2013 American Transplant Congress
Undetected Lesion as a Risk Factor for Recurrence in Patients Transplanted for HCC, The
NYU SOM, New York, NY; U of M, Ann Arbor, MI
Background: OLT is the definitive treatment for HCC. Vascular invasion, tumor size, and proliferation are known risk factors for recurrence post-OLT. Undetected lesions <1cm are…2013 American Transplant Congress
Children Develop De Novo Anti-HLA Antibodies (Abs) Following Kidney Transplantation at a Higher Incidence Than Adults: An Analysis of the NIH CTOT/CCTPT-02 Study
The NIH CTOT/CCTPT-02 examined the development of post transplant de novo anti-HLA Abs in unsensitized kidney transplant recipients. It is a multi-center observational study that…2013 American Transplant Congress
IL37 Controls IL18 Induced Pro-Inflammatory Cytokine Expression by Tubular Cells and Attenuates Renal Ischemia-Reperfusion Injury
IL37 is a newly described member of the IL-1 family,which is anti-inflammatory by its inhibition of pro-inflammatory cytokine production. While human IL37 has no murine…2013 American Transplant Congress
Rapamycin-Induced Augmentation of the CD8 T Cell Response to a Latent Viral Infection Is Inhibited by CTLA4-Ig
Latent viral infections are a major concern among immunosuppressed transplant patients. Treatment with belatacept, a CTLA4-Ig fusion protein, was shown to reduce toxicity in kidney…2013 American Transplant Congress
Epitope Matching Outperforms Traditional Antigen Matching as a Predictor of De Novo Donor Specific Antibody Development after Renal Transplantation
Hypothesis:An epitope based HLA matching approach will be predictive of de novo Donor Specific Antibody (dnDSA) development after renal transplantation.Methods:315 consecutive renal transplants were performed…2013 American Transplant Congress
Cell Necrosis and Immune Activation: Does Injury Alter Acquired Alloimmunity?
Emory Transplant Center, Atlanta, GA
Adaptive immune responses are directed by specific recognition of antigen but are also driven by general contextual signs of injury. Organ transplantation provides both of…