ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Early Indicators of Kidney Graft Injury Mediated by Class II Donor Specific Antibodies (DSAII)

    E. Rodrigo, L. Cornell, B. Chopra, H. Amer, P. Dean, M. Stegall, F. Cosio

    Nephrology, Transplant Center, Mayo Clinic, Rochester, MN; Pathology, Transplant Center, Mayo Clinic, Rochester, MN; Surgery, Transplant Center, Mayo Clinic, Rochester, MN

    Introduction. Pre-transplant DSAII is associated with chronic antibody mediated rejection/transplant glomerulopathy (TG) and high risk of graft loss (GL). However, not all DSAII result in…
  • 2013 American Transplant Congress

    Expanding the Limits of the Expanded Criteria Donor

    L. Assis, M. Cristelli, T. Claudia, S. Miranda, M. Franco, T. Sandes-Freitas, M. Salenave, H. Tedesco, J. Medina- Pestana

    Nephrology Division, Hospital do Rim e Hipertensão, Sao Paulo, Brazil

    Background: Use of grafts from expanded criteria donors (ECD) has increased significantly in recent years. Acceptable reported outcomes may increase the limits of acceptance and…
  • 2013 American Transplant Congress

    Risk Factors in Venous Thrombosis of Renal Grafts from Deceased Non Heart-Beating Donors

    M. Molina, E. Gonzalez, N. Polanco, L. Garcia-Puente, A. Sevillano, E. Gutierrez, E. Morales, A. Hernandez, J. Morales, A. Andres

    Nephrology, Hospital 12 Octubre, Madrid, Spain

    Background: The deceased donor kidney transplant to non heart-beating may have a higher rate of venous thrombosis (VT).The aim of this study is to analyze…
  • 2013 American Transplant Congress

    Encapsulated Human Mesenchymal Stem Cells Reduce Alpha-Smooth Muscle Actin and Increase Matrix Metalloproteinase-9 Expression during Liver Fibrosis

    R. Meier, R. Mahou, P. Morel, Y. Muller, P. Christofilopoulos, C. Wandrey, C. Gonelle-Gispert, L. Buhler

    Visceral and Transplantation Surgery, Surgical Research Unit, Department of Surgery, University Hospitals of Geneva, Geneva University, Geneva, Switzerland; Laboratory of Chemical Biotechnology, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland; Orthopedic Surgery, University Hospitals of Geneva, Geneva University, Geneva, Switzerland

    INTRODUCTION: Mesenchymal stem cells (MSCs) transplantation has been suggested to be effective for the treatment of liver fibrosis, but the mechanisms of action are not…
  • 2013 American Transplant Congress

    Immunosuppression Regimen and the Risk of Acute Rejection in HIV-Infected Kidney Transplant Recipients

    J. Locke, N. James, S. Mehta, P. Pappas, R. Mannon, N. Desai, R. Montgomery, D. Segev

    University of Alabama at Birmingham, Birmingham; Johns Hopkins University, Baltimore

    Background: Kidney transplantation has been established as the therapy of choice for the treatment of end stage renal disease among appropriately selected HIV-infected (HIV+) individuals.…
  • 2013 American Transplant Congress

    Evaluation of Immunocompetence in Tolerant Chimeric Recipients of Hematopoietic Stem Cell/Renal Transplants

    J. Leventhal, L. Bozulic, M. Badder, M. Elliott, M. Ison, S. Ildstad

    Northwestern University, Chicago, IL; Regenerex, LLC, Louisville, KY; Institute for Cellular Therapeutics, University of Louisville, Louisville, KY

    We have established high levels of durable chimerism and immunosuppression-free graft survival without GVHD or engraftment syndrome in recipients of living donor facilitating cell/hematopoietic stem…
  • 2013 American Transplant Congress

    Potential Importance of 3 Year Surveillance Biopsies in Renal Transplantation

    M. Willicombe, C. Roufosse, P. Brookes, J. Galliford, A. McLean, T. Cook, D. Taube

    Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom; Histopathology, Hammersmith Hospital, London, United Kingdom

    Most renal transplant surveillance biopsies [SBx] are taken within the first 12 months of transplantation and there is growing evidence that the detection of subclinical…
  • 2013 American Transplant Congress

    Treg Express a Unique Pattern of Trafficking Molecules and Differentially Rely on LFA-1 for Migration Compared to Effector T Cells

    C. Brinkman, J. Bromberg

    University of Maryland, Baltimore

    Introduction: Selective interference with or enhancement of Treg function and/or migration are potentially therapeutically useful. However, to date the molecules which govern Treg migration seem…
  • 2013 American Transplant Congress

    KPC Infection – A Real Threat to Kidney Transplant Recipients

    M. Cristelli, G. Basso, E. Costa-Neto, D. Lopes, T. Sandes-Freitas, V. Silva, A. Gales, S. Moreira, H. Tedesco, J. Medina- Pestana

    Hospital do Rim e Hipertensão, Sao Paulo, Brazil

    Introduction: Carbapenemase-producing enterobacteriaceae (KPC) infection has become a world public health issue since its first detection in 1996. Intuitively, immunocompromised patients might be at higher…
  • 2013 American Transplant Congress

    Survival of Free and Encapsulated Islet Xenografts Transplanted in the Mouse Bone Marrow, The

    R. Meier, J. Seebach, P. Morel, R. Mahou, D. Bosco, T. Berney, L. Buhler, Y. Muller

    Visceral and Transplantation Surgery, Cell Isolation and Transplantation Center, Department of Surgery, University Hospitals of Geneva, Geneva University, Geneva, Switzerland; Division of Clinical Immunology and Allergology, Department of Internal Medicine, University Hospitals of Geneva, Geneva University, Geneva, Switzerland; Laboratory of Chemical Biotechnology, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland

    Objectives: Bone marrow (BM) has been recently shown to be an alternative and potentially immune-privileged site for islet transplantation. The aim of the study was…
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