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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Adenosine A2A Receptor (A2AR) Agonist Apadenoson Promotes Survival in K28-hACE2 Mice and Syrian Hamsters Infected with Sars-CoV-2

    P. Chhabra1, B. Mann2, M. Ma1, S. Feldman3, J. Linden4, K. L. Brayman1

    1Department of Surgery, University of Virginia Health System, Charlottesville, VA, 2Department of Infectious Diseases, University of Virginia Health System, Charlottesville, VA, 3Center for Comparative Medicine, University of Virginia Health System, Charlottesville, VA, 4Department of Nephrology, University of Virginia Health System, Charlottesville, VA

    *Purpose: To determine if Apadenoson or Regadenoson has a therapeutic effect in attenuating hyper-inflammation and improving survival rate in K18-hACE2mice or Syrian hamsters infected with…
  • 2022 American Transplant Congress

    Covid-related Neonatal Cholestasis?: Liver Transplantation In Three Infants With Intrauterine Or Perinatal Covid Exposure

    S. Sakhuja1, K. Patel1, N. T. Galvan2

    1Baylor College of Medicine, Houston, TX, 2Baylor College of Medicine, Houston, TX

    *Purpose: The COVID pandemic presents a unique set of challenges during pregnancy including thromboembolic complications, direct placental infection, transplacental transmission, and systemic hyperinflammatory state. The…
  • 2022 American Transplant Congress

    Emphysematous Cystitis in a Lung Transplant Recipient with BK Viremia

    D. Razia, J. Klein, H. Mohamed, A. Arjuna

    Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ

    *Purpose: Emphysematous cystitis (EC) is a rare urinary tract infection from E. coli or K. pneumoniae in diabetics or immunocompromised individuals, resulting in sepsis and…
  • 2022 American Transplant Congress

    Perioperative Cardiovascular Outcomes of Pre-Transplant ECMO in Recipients of Lung Transplant

    F. Anjum1, R. Munshi2, A. M. Courtwright1, M. M. Crespo1, J. C. Salgado1, J. D. Christie1, V. N. Ahya1, N. Patel1, D. Hadjiliadis1, E. Clausen1, M. Cevasco3, E. E. Cantu3, C. A. Bermudez3, J. M. Diamond1

    1Pulmonary and Critical Care, University of Pennsylvania, Philadelphia, PA, 2Nassau University Medical Center, East Meadow, NY, 3Cardiovascular Surgery, University of Pennsylvania, Philadelphia, PA

    *Purpose: Use of extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplant (BTT) has increased over time. While similar one-year and overall survival has…
  • 2022 American Transplant Congress

    The Implication of Donor Race on the Post-Liver Transplant Prognosis of Patients with Nonalcoholic Steatohepatitis: Analysis of UNOS Database

    D. U. Lee1, J. Han2, J. Kwon2, K. Chang2, K. Lee2, G. Fan2, N. Urranaga1, D. Maluf3, C. Bhati1, K. Shetty1

    1Department of Gastroenterology and Hepatology, University of Maryland, Baltimore, MD, 2Tufts Medical Center, Boston, MA, 3University of Maryland, Baltimore, MD

    *Purpose: Prior studies have suggested liver transplant (LT) recipients who receive their grafts from minority donors may potentially suffer higher rates of graft complications. In…
  • 2022 American Transplant Congress

    The Role of T Lymphocyte Subsets in Kidney Transplantation

    L. Vagiotas1, A. Xochelli2, E. Sampani3, V. Nikolaidou2, D. Asouchidou2, E. Kasimatis3, N. Antoniadis1, M. Daoudaki4, M. Stangou3, A. Papagianni3, G. Tsoulfas1, A. Fylaktou2

    1Division of Organ Transplantation, Department of Surgery, Aristotle University Medical School, Hippokration Hospital, Thessaloniki, Greece, 2National Peripheral Histocompatibility Center, Immunology Department, Hippokration Hospital, Thessaloniki, Greece, 3Department of Nephrology, Aristotle University Medical School, Hippokration Hospital, Thessaloniki, Greece, 4Laboratory of Biological Chemistry, Faculty of Medicine Aristotle University of Thessaloniki, Thessaloniki, Greece

    *Purpose: Impairment of cellular immune function in kidney transplant candidates is not concomitantly restored with the recovery of renal function, as alloimmune response and implementation…
  • 2022 American Transplant Congress

    Adoptive Transfer OfMesenchymal Stem Cells Activates Hedgehog/SMO/Gli1 Signaling And Inhibits STING-mediated Innate Immune Response In Liver Transplant Inflammatory Injury

    D. Xu1, X. Qu1, Y. Tian1, M. Sheng1, Y. Lin1, Y. Zhan1, F. M. Kaldas1, R. W. Busuttil1, D. G. Farmer1, J. W. Kupiec-Weglinski1, Q. Xia2, B. Ke1

    1Surgery, Dumont - UCLA Transplant Ctr, Los Angeles, CA, 2Liver Surgery, Shanghai Jiaotong University School of Medicine, Shanghai, China

    *Purpose: The stimulator of interferon genes (STING) pathway has been recognized as a crucial signaling cascade of the innate immune system. Activation of the Hedgehog…
  • 2022 American Transplant Congress

    NecroX-7 Ameliorate FK506-Induced Nephrotoxicity in LLC-PK1 Cells (Pig Kidney Epithelial Cells)

    H. J. Jang

    Surgery, University of Ulsan, Gangneung Asan Hospital, Gangneung, Korea, Republic of

    *Purpose: Tacrolimus (FK506) is an immunosuppressant agent that is frequently used to prevent rejection of solid organs upon transplant. However, nephrotoxicity due to apoptosis and…
  • 2022 American Transplant Congress

    The Cost of Procuring Deceased Donor Livers: Evidence from OPO Cost Reports 2013-2018

    J. Bragg-Gresham1, T. Peters2, F. McCormick3, J. Roberts4

    1University of Michigan, Ann Arbor, MI, 2University of Florida, Jacksonville, FL, 3Bank of America (Former), Walnut Creek, CA, 4University of California-San Francisco, San Francisco, CA

    *Purpose: The cost of procuring deceased donor organ for transplantation include costs for the assessment of potential organ donors, maintenance of the donor while waiting…
  • 2022 American Transplant Congress

    Increased Survival Benefit Amongst Highest Priority Candidates Undergoing Heart Transplant Following the New Us Heart Allocation System

    S. Tolmie1, W. Parker2

    1Pritzker School of Medicine, University of Chicago, Chicago, IL, 2Department of Medicine, Section of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, IL

    *Purpose: A key policy change in the new US heart allocation system was splitting the previous highest status (1A) into statuses 1, 2, and 3…
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