2022 American Transplant Congress
Contributions of Allogenicity and Antigen Presentation to Regulatory B Cell Suppression
Center for Transplantation Sciences, Boston, MA
*Purpose: We previously generated in vitro Toll-like receptor (TLR)-activated B cells became regulatory B cells (Bregs) that suppress T cell proliferation and promote allograft tolerance.…2022 American Transplant Congress
Contacts Between Organ Donor Families and Their Recipients is Therapeutic for Both Sides in Most Cases
Nicholas Green Foundation, La Canada Flintridge, CA
*Purpose: The study's purpose is to discover if making it possible for organ donor families to contact their recipients -- when both sides express the…2022 American Transplant Congress
Biopsy and Blood Gene Expression Profiles Distinguish Injury, Subclinical and Clinical Rejection in Kidney Transplant Recipients
1Scripps Health, La Jolla, CA, 2Northwestern University, Chicago, IL
*Purpose: We analyzed serial gene expression profiles in paired blood and biopsies from kidney transplant recipients phenotyped with a comprehensive clinical algorithm. We compared disease…2022 American Transplant Congress
Impact of the Weekend Effect on Adult and Pediatric Liver or Kidney Offer Acceptance
Transplant Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, MA
*Purpose: Weekends may impose resource and manpower constraints on hospitals. Studies using data from prior allocation schemas showed increased adult organ discards on weekends. We…2022 American Transplant Congress
Characteristics of OPOs with Increased Education Spending, 2013-2018
*Purpose: OPO spending on education would be expected to increase donor registration and increase the number of donors. Using data from multiple sources, we examined…2022 American Transplant Congress
Early Evaluation Of The Impact Of Change In UNet Organ Refusal Code Reasons On Us Transplant Center Organ Offers
*Purpose: On December 2, 2021 a new set of organ refusal codes was implemented in DonorNet. These new codes were meant to provide more relevant…2022 American Transplant Congress
Regulatory T Cells Suppress Memory IFN-Gamma Production in Highly Sensitised Patients
*Purpose: Highly sensitized patients (HS) present worse long-term outcome after transplantation compared to those without donor-specific antibodies (DSA). It has been suggested that desensitisation using…2022 American Transplant Congress
Fixed-Dose Rituximab for Pre-Transplant DSA in Kidney Transplant Recipients
*Purpose: Donor specific antibodies (DSAs) occur in 15-30% of kidney transplant recipients (KTRs) and are associated with rejection and graft loss. Rituximab (RTX), an antiCD20…2022 American Transplant Congress
Equivalence of Pediatric Paper and Electronic-Based Patient-Reported Outcome Measures: Findings from a Systematic Review
*Purpose: Integration of patient reported outcome measures (PROMs) in routine clinical care reduces utilisation of health care services and improves patient outcomes. Electronic versions of…2022 American Transplant Congress
Immunomodulation in Lung Transplant May Facilitate Transformation of Usual Interstitial Pneumonia Into Pleuroparenchymal Fibroelastosis
*Purpose: Pleuroparenchymal fibroelastosis (PPFE) is a rare but distinctive manifestation of interstitial lung disease (ILD) characterized by a highly elastotic pattern of lung fibrosis. Its…
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