2013 American Transplant Congress
Role of Graft Non-Hematopoietic Cells in Organ Transplant Tolerance, The
Success of organ transplantation currently depends on life-time immunosuppression, resulting in severe side effects. Induction of specific tolerance is ideal, which actually spontaneously occurs following…2013 American Transplant Congress
Impact of the Determination of HLA Antibodies in Kidney Transplant over Ten Years of Monitoring
Nephrology, Hospital 12 de Octubre, Madrid, Spain
Objetive: The goal of this study was to determine the prevalence of anti-HLA antibodies and the clinical outcome in patients with functioning renal graft over…2013 American Transplant Congress
Everolimus (RAD001) Treatment Effect in Liver Transplantation – A Rational Approach To Quantify the mTOR Effect
The H2304 Study Group, Basel, Switzerland
Background: 12M study results of study CRAD001H2304 (NCT00622869) demonstrated superior renal function and comparable efficacy, including fewer and less severe treated BPAR with everolimus (EVR)…2013 American Transplant Congress
Anti-HLA DP Alpha Alloantibodies Are Associated with High Antibody Levels and Correlate with Individual HLA-DP Beta Epitopes in Renal Transplant Candidates and Recipients
University of Cincinnati, Cincinnati
Anti-HLA DP antibodies have been associated with renal allograft rejection and/or positive crossmatches. While the reactivity of anti-HLA DP Beta antibody (DPΒ-Ab) is described, less…2013 American Transplant Congress
Increased Incidence of Non Anastomotic Biliary Strictures in Case of Donation after Circulatory Death Versus Donation after Brain Death Liver Transplantation but Equivalent Graft and Patient Survival
Because of the concerns regarding short & long-term outcomes after Liver Transplantation (LTx) using Donation after Circulatory Death (DCD) compared to Donation after Brain Death…2013 American Transplant Congress
Renal Transplantation with Final Allocation Based on the Virtual Crossmatch: Outcomes at 5 Years
Background: Use of the virtual crossmatch (VC) has been shown to increase the efficiency of identifying compatible renal transplant recipients from a given donor. However…2013 American Transplant Congress
Lymphotoxin Regulates Treg Entry into the Lymph Node
University of Maryland, Baltimore
Introduction: Lymphotoxin (LT) regulates the organization, development, and maintenance of lymphoid organs. Lymphotoxin beta receptor (LTΒR) signaling has been implicated in T cell migration in…2013 American Transplant Congress
Donor-Derived Dendritic Cells (DC) Mobilized from Cardiac Allografts Initiate T-Cell Allo-Recognition through the Direct Pathway Via Recipient’s DC
The mechanism(s) by which donor and recipient APC, in particular dendritic cells (DC), prime T cells with direct and indirect allo-specificities in lymphoid organs remains…2013 American Transplant Congress
Enoxaparin Targets Heparanase To Elicit Its Anti-Metastatic Activity
Rationale: Extracellular matrix (ECM) remodeling plays an important role in cancer development. Heparanase is an endo-Β-glycosidase that degrades the ECM heparan sulfate (HS), thereby enhancing…2013 American Transplant Congress
Analysis of Survival and Neoplasm Recurrence in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma: Association with Immunohistochemical Profile and Tumor Characteristics
Unit of Liver Transplantation, State University of Campinas, Campinas, São Paulo, Brazil
Introduction: Although overall survival rates have been around 70% after five years, recurrence of hepatocellular carcinoma (HCC) has indices in literature ranging from 6 to…
American Transplant Congress abstracts