2013 American Transplant Congress
Protective Effect of Nrf2-keap1 Pathway on Islet Cells Using Islet Isolation Model
Background: Nuclear factor erythroid-derived 2-related factor (Nrf2) is a transcription factor that regulates basal activity and coordinated induction of numerous genes encoding antioxidant and phase…2013 American Transplant Congress
West Nile Virus (WNV) Epidemic during 2012 in the Western United States: High Number of IgM Anti-WNV Reactives but No WNV RNA+ Organ Donors
WNV is a neurotropic flavivirus. Humans are accidental, dead-end hosts for WNV. Symptoms usually develop 2-15 days after exposure and viremia begins prior to symptoms…2013 American Transplant Congress
Differing Responsiveness of EQ-5D Preference Valuations to Solid Organ Transplantation: Implications for Cost-Utility Analyses
Introduction: EuroQoL (EQ-5D) health-related quality of life surveys can be reported as health status scores and preference valuation (PV) utilities. Our aim was to evaluate…2013 American Transplant Congress
Rabbit ATGs Modulate the Leukocyte-Endothelium Interactions in Both Naïve and Adult Endothelial Cells
IntroductionPolyclonal antithymocyte globulins (ATGs) are immunosuppressive drugs widely used in induction of immunosuppression and treatment of acute rejection after solid organ transplantation. The aim of…2013 American Transplant Congress
Occult Hepatitis B Virus (HBV) Infections among Organ and Tissue Donors: Lessons Learned from "Real Time" Testing
Background: Currently Hepatitis B surface Antigen (HBsAg) and Hepatitis B core Antibody (anti-HBc) screening is used to reduce organ/tissue-transmitted HBV. Although this serologic testing algorithm…2013 American Transplant Congress
Validation of Urine CXCL10 for Diagnosis of Subclinical and Clinical Rejection in Pediatric Kidney Transplants
University of Manitoba, Winnipeg, Canada
Non-invasive testing for detection of acute rejection is needed to improve outcomes. Urinary CXCL10 has been validated as a biomarker of tubulitis in adults and…2013 American Transplant Congress
7 Years Experience with Multiplex TMA-NAT-Based Assay for HIV and HCV Screening among Organ and Tissue Donors – Definitive Report
BACKGROUND Transplant professionals must be able to rely on organ and tissue screening tests to accurately detect the presence of viruses and their antibodies. Antiviral…2013 American Transplant Congress
Comparison of Efficacy and Mechanism of Intact and Fc-Modified Anti-CD154 Antibodies in Tolerance Induction
Emory University, Atlanta, GA; Bristol-Myers Squibb, Princeton, NJ
Blockade of CD40-CD154 interactions during T cell priming has been shown to be a highly effective means of inducing long-term survival of allografts and transplantation…2013 American Transplant Congress
Practices and Attitudes toward Donor Pain Control in Adult to Adult Living Donor Liver Transplantation Cohort Study (A2ALL)
Lahey Clinic; Northwestern U; U of Colorado
IntroductionClinicians at 9 A2ALL centers were surveyed about practices and attitudes toward pain control after donor hepatectomy.MethodsResponses were collected via Survey Monkey. A surgeon (S),…2013 American Transplant Congress
Tacrolimus Dose and Trough Blood Levels in a US Liver Transplant Population
ObjectiveTo examine tacrolimus (TAC) dose over time and by TAC trough levels in liver transplant (LTX) patients.MethodsA retrospective analysis of transplanted liver and a prescription…