2013 American Transplant Congress
Subtle Deregulation of Circadian Rhythm in Mice with Partial A20 Knockdown Severely Impacts Lipid Metabolism Following Partial Hepatectomy Causing Defective Regeneration and Increased Lethality
Overexpression of A20 promotes liver regeneration (LR), but contribution of physiologic A20 to LR remains unclear. We performed 2/3 partial hepatectomy (PH) in A20 heterozygous…2013 American Transplant Congress
Tolerance Induction Changes Lymph Node Structure and Function
Centre for Vascular and Inflammatory Diseases, University of Maryland, Baltimore, MD
BackgroundCostimulatory blockade plus donor-specific splenocyte transfusion (DST) induces long-term graft acceptance, however the mechanism by which this tolerance occurs remains incompletely defined. The lymph node…2013 American Transplant Congress
Ex Vivo Expanded Human Regulatory T Cells Are Potent Suppressors but May Be Short-Lived
Translational Research Program, Benaroya Research Institute at Virginia Mason, Seattle, WA
Infusion of host derived ex vivo expanded regulatory T cells (eTregs) is an attractive therapeutic strategy for promotion of transplant tolerance. We report herein that…2013 American Transplant Congress
Discrepancy between Biological Age and Calendar Age: A Large Histology Study in Implantation Biopsies, The
University Hospitals Leuven, Leuven, Belgium; Hasselt University, Hasselt, Belgium
BACKGROUNDThe histology and function of kidneys is thought to deteriorate with increasing age. Replicative senescence, associated with telomere shortening, plays an important role in this…2013 American Transplant Congress
Impact of Intravenous Immunoglobulins on Anti-HLA Immunization after Renal Allograft Nephrectomy
IntroductionRenal allograft nephrectomy is a major risk factor for anti-HLA alloimmunization and antibody-mediated rejection after retransplantation. No preventive strategy has been evaluated.MethodsWe retrospectively analyzed anti-HLA…2013 American Transplant Congress
Effectiveness in Kidney Donation of Uncontrolled Donation after Cardiac Death (UDCD) Program with Out-of-Hospital Deceased People
Thousands of people suffer out-of-hospital cardiac arrest worldwide every year, death being declared in situ after 30min. of unsuccessful advanced CPR maneuvers. Some cases could…2013 American Transplant Congress
Recipient’s Conventional Dendritic Cells (DC) Are the Mediators of the Beneficial Effects of Immunosuppressive DC-Based Therapies in Cardiac Transplantation
During the past 15 years, therapies based on administration of donor- or recipient-derived immunosuppressive (IS) / tolerogenic dendritic cells (DC), alone or in combination with…2013 American Transplant Congress
Have Livers? Will Travel! Multiple Listings To Expedite Liver Transplantation
Surgery, MGH, Boston, MA; Surgery, UCSF, San Francisco, CA
Background Geographic disparity in access to liver transplantation (LT) exists. This study compared demographics, waitlist, and transplant dynamics of multi-listed (ML) versus singly listed (SL)…2013 American Transplant Congress
Experience with Sorafenib in the Liver Transplant Population
U of M, Ann Arbor, MI; NYU SOM, New York, NY
Background: HCC is a common indication for OLT. TACE and RFA are used as bridge therapies. These rarely result in complete eradication. Subsequent spread throughout…2013 American Transplant Congress
Impact of Pre-Transplant Amputation on Renal Allograft Outcomes
Introduction: United States Renal Data System (USRDS) was used to assess renal allograft outcomes in patients with pre- transplant amputation (AMP).Methods: We used an incident…
American Transplant Congress abstracts