ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Analysis of Graft Loss in Hand Transplant Recipients in the Western World – Cause for Concern?

    K. Ravindra, V. Gorantla

    Surgery, Duke University, Durham; University of Pittsburgh, Pittsburgh

    Introduction: In the 14 years since the first successful hand transplant, the procedure has become established and performed around the world. This is an analysis…
  • 2013 American Transplant Congress

    Interleukin-1 Receptor Antagonist Delays Progression of Liver Fibrosis

    R. Meier, Y. Muller, S. Lacotte, G. Mentha, P. Morel, C. Gonelle-Gispert, L. Buhler

    Visceral and Transplantation Surgery, Surgical Research Unit, Department of Surgery, University Hospitals of Geneva, Geneva University, Geneva, Switzerland

    Introduction: Liver fibrosis represents a wound healing response to chronic insults affecting both candidates for liver transplantation and transplanted patients. Interleukin-1Β (IL1Β) has been proposed…
  • 2013 American Transplant Congress

    Intragraft Gene Expression of Polyomavirus Associated Nephropathy

    M. Naesens, T. Sigdel, N. Salomonis, S. Roedder, X. Gao, M. Vitalone, D. Kuypers, E. Lerut, M. Sarwal

    California Pacific Medical Center Research Institute, San Francisco; University Hospitals Leuven, Leuven, Belgium

    BACKGROUNDAlthough the histopathology of polyomavirus nephropathy (PVAN) is very often indistinguishable from T-cell mediated rejection (TCMR), the outcome of both diseases is very different. The…
  • 2013 American Transplant Congress

    Causes of Kidney Transplant Failure: Specific Diseases Versus Non-Specific Injury, The

    M. Naesens, D. Kuypers, K. De Vusser, Y. Vanrenterghem, E. Lerut

    University Hospitals Leuven, Leuven, Belgium

    BACKGROUNDThe relative impact on renal allograft outcome of specific histological diseases (e.g. acute T-cell mediated rejection [TCMR], acute and chronic antibody-mediated rejection [aABMR and cABMR],…
  • 2013 American Transplant Congress

    Urinary Protein Excretion in Non-Renal Transplant Patients – Does mTOR-Inhibitor Treatment Matter?

    G. Junge, P. De Simone, J. Fung, S. Kohler, F. Saliba

    The H2304 Study Group, Basel, Switzerland

    BackgroundThe interplay of glomerular filtration and tubular absorption of proteins with various molecular weights defines the pattern and magnitude of daily urinary protein excretion (UPE).…
  • 2013 American Transplant Congress

    Analysis of Leukocyte-Endothelium Interactions after Immunosuppression by Means of Intravital Microscopy in the Human Placenta

    A. Beiras-Fernandez, S. Walther, A. Beiras, E. Thein

    Cardiothoracic and Vascular Surgery, JW Goethe University Hospital, Frankfurt, Germany; Walter-Brendel Institute of Experimental Medicine, Munich, Germany; Universidad de Santiago de Compostela, Santiago, Spain

    Background: The failure of translating results obtained in animal models into humans is one of the main problems in medical research. The aim of our…
  • 2013 American Transplant Congress

    CD68 Positive Glomerulitis Predicts the Development of Transplant Glomerulopathy in Patients with Cellular Rejection

    M. Willicombe, C. Roufosse, P. Brookes, J. Galliford, A. McLean, T. Cook, D. Taube

    Imperial College Kidney and Transplant Centre, London, United Kingdom; Histopathology Department, Imperial College NHS Trust, London, United Kingdom

    Transplant glomerulopathy [TG] has a very poor prognosis and is almost always associated with eventual graft failure. The risk of TG is increased in patients…
  • 2013 American Transplant Congress

    Living Donor Conversion Rate as a Quality Measure for Kidney Transplant Programs

    E. Woodle, B. Woodle, A. Girnita, M. Cuffy, S. Shah, J. Schold, J. Gill

    U of Cincinnati, Cincinnati; Cleveland Clinic, Cleveland; U of British Columbia, Canada

    Kidney transplant (KTxp) program quality is assessed by risk adjusted wait list (WL) mortality, time to deceased donor (DD) Txp, and patient (pt) and graft…
  • 2013 American Transplant Congress

    Tolerance Related Gene Expression in Urine from Kidney Transplant Recipients

    M. Jenkins, M. Runglall, I. Rebollo-Mesa, P. Mobillo, Y. Kamra, E. Nova-Lamperti, S. Norris, GAMBIT Consortium, G. Lord, R. Lechler, M. Hernandez-Fuentes

    King's College London, MRC Centre for Transplantation, London, United Kingdom; NIHR Comprehensive Biomedical Research Centre, At Guy's and St Thomas' Hospital NHS Foundation Trust in Partnership with King's College London and King's College Hospital, London, United Kingdom; www.GAMBITstudy.co.uk, London, United Kingdom; King's Health Partners, London, United Kingdom

    Background: Long-term graft survival in renal transplantation relies on continuous immunosuppression with drugs that can cause high morbidity. Tolerance is an emerging clinically recognised event.…
  • 2013 American Transplant Congress

    Anti-HLA Immunization Profile at the Time and after Renal Allograft Nephrectomy

    C. Leibler-Romand, M. Matignon, F. Roudot-Thoraval, L. Salomon, D. Charron, P. Lang, C. Suberbielle, P. Grimbert

    Nephrology, Henri Mondor, APHP, Créteil, France; Public Health, Henri Mondor, APHP, Créteil, France; Urology, Henri Mondor, APHP, Créteil, France; Histocompatibility, Saint Louis, APHP, Paris, France

    IntroductionAllograft nephrectomy is a major risk factor for alloimmunization and can increase time on the waiting-list and acute antibody-mediated rejection. Anti-HLA immunization profile, DSA and…
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