ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Is Mycophenolic Acid AUC a Good Pronostic Factor for BK Viremia?

    T. Lamy, B. Hurault de Ligny, J. Dina, D. Debruyne, V. Chatelet, T. Lobbedez, M. Ficheux, N. Bouvier

    Service de Néphrologie, CHRU Clemenceau, Caen, France; Service de Virologie, CHRU Clemenceau, Caen, France; Service de Pharmacologie, CHRU Cote de Nacre, Caen, France

    Background: BK virus can induce severe impairment of graft function after kidney transplantation. Many studies have evaluated the best strategy to prevent BK-induced interstitial nephritis.…
  • 2013 American Transplant Congress

    Concurrent Silencing of TLR and Kinase Signaling Pathways To Prevent Allograft Rejection in Heart Transplantation

    X. Zhang, D. Lian, X. Zheng, D. Chen, K. Siu, N. Johnston, D. Quan, W. Min

    Surgery, Pathology, and Oncology, University of Western Ontraio, London, ON, Canada; Multi-Organ Transplant Program, London Health Science Centre, London, ON, Canada

    Background: Toll-like receptors (TLRs) act as initiators and conductors responsible for both innate and adaptive immune responses in transplantation. The mammalian target of rapamycin (mTOR)…
  • 2013 American Transplant Congress

    Old DCD Kidneys to Old Recipients Have a Good Outcome; Is That the Solution for the Old Patients on the Waiting List?

    M. Jameel, M. Qasim, L. Szabo, M. Stephens, A. Asderakis

    Cardiff Transplant Unit, University Hospital of Wales, Cardiff, United Kingdom

    The proportion of DCD donors among deceased transplants in UK has increased from 8% to 40 % with a striking increase in the mean age…
  • 2013 American Transplant Congress

    Clinical and Mechanistic Study of How Innate Immunity Gene Polymorphisms Can Affect Influenza Vaccine Responses Post-Transplant, A

    A. Egli, D. Santer, D. O'Shea, A. Baluch, M. Joyce, L. Lisboa, L. Tyrrell, M. Houghton, A. Humar, D. Kumar

    University of Alberta, Edmonton, Canada

    Background: Interferons modulate the innate and adaptive immune response to viruses and vaccines. Transplant recipients respond poorly to influenza vaccine. The contribution of IFNΛ and…
  • 2013 American Transplant Congress

    Salt Intake and Post-Transplant Hypertension in Kidney Transplant Recipients

    E. Rodrigo, E. Monfá, G. Fernández-Fresnedo, J. Ruiz, C. Piñera, R. Palomar, C. Gómez-Alamillo, M. Arias

    Nephrology, Hospital Marqués de Valdecilla, Santander, Spain

    Up to 90% of kidney transplant recipients (KTx) develop hypertension. Both systolic and diastolic post-transplant hypertension relate to patient and allograft survival. In the general…
  • 2013 American Transplant Congress

    Liver Transplantation from Donors with past History of Malignancies: A Single Center Experience

    T. Benkö, S. Radünz, M. Banysch, F. Saner, A. Paul, J. Treckmann

    Dept. of General- and Transplantation Surgery, University Clinic, Essen, Germany

    Introduction: The demand for transplantable organs exceeds donor supply. Transplantation of organs from donors with past history of malignancy is controversial, and the transmission of…
  • 2013 American Transplant Congress

    Double-Deficiency for RORγt and T-Bet Drives Th2-Mediated Allograft Rejection in Mice

    M. Sabet-Baktach, J. Rovira, S. Farkas, E. Eggenhofer, M. Lantow, G. Koehl, M. Dahlke, H. Schlitt, E. Geissler, A. Kroemer

    Department of Surgery, University Clinic of Regensburg, Regensburg, Germany

    While Th1, Th2 and Th17 cells are thought to be major effector cells in adaptive alloimmune responses, their respective contribution to allograft rejection remains unclear.…
  • 2013 American Transplant Congress

    Analysis of Patient Survival Outcome between Waiting List Adult HUS Patients Who Received Kidney Transplants (KT) and Those Who Did Not

    A. Santos, X. Wen, I. Zendejas, M. Casey, C. Bucci, R. Aiyer, S. Rehman

    Univ of Florida, Gainesville, FL

    Purpose: Our study aimed to determine the difference in survival probability between HUS patients listed for transplant who received a KT and those who remained…
  • 2013 American Transplant Congress

    Ribavirin Is Highly Efficient at Treating Chronic Hepatitis-E-Virus Infection in Organ-Transplant-Patients: A Retrospective Multicenter French Study

    N. Kamar, M. Bismuth, S. Hillaire, L. Rostaing, V. Mallet

    Toulouse University Hospital, Toulouse, France; Montpellier University Hospital, Montpellier, France; Foch Hospital, Surresne, France; Cochin University Hospital, Paris, France

    Background: To date, there is no established therapy for hepatitis-E-virus (HEV) infection. The aims of this retrospective multicenter study were to assess the efficacy and…
  • 2013 American Transplant Congress

    Peripheral NK Cell Repertoire Is Modulated by Different Immunosuppressive Drugs Following Kidney Transplantation, The

    C. Neudoerfl, B. Mueller, C. Blume, K. Daemen, M. Stevanovic-Meyer, J. Keil, F. Lehner, H. Haller, C. Falk

    Transplant Immunology, Hannover Medical School, Hannover, Germany; Nephrology and Hypertension, Hannover Medical School, Hannover, Germany; Abdominal and Transplant Surgery, Hannover Medical School, Hannover, Germany

    Introduction: In the context of kidney transplantation (KTx), little is known about the involvement of Natural Killer (NK) cells in the immune reaction leading to…
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