2013 American Transplant Congress
Long-Term Outcomes Following Acute Rejection in Kidney Transplant Recipients: An ANZDATA Analysis
Declining rates of acute rejection (AR) and an apparent dissociation between acute rejection incidence and 1 year graft survival have raised questions as to the…2013 American Transplant Congress
Rabbit Antithymocyte Globulin Induction Therapy Induces Donor-Specific HeliosnegFOXP3pos Regulatory T Cells in Kidney Transplant Patients
Introduction: Repopulation of regulatory T cells (Treg) after rabbit antithymocyte globulin (rATG) induction therapy in kidney transplant patients occurs via either thymopoiesis or homeostatic proliferation.…2013 American Transplant Congress
Epidemiology and Prevention Approaches for Cytomegalovirus (CMV) Disease in CMV-Seropositive Kidney Transplant (KT) Recipients: Results from a Multicenter, Prospective, Cohort Study (OPERA Study)
Background: Although much is known about the incidence and prevention strategies in CMV-seronegative KT recipients, there is comparatively little information on these issues in CMV-seropositive…2013 American Transplant Congress
Impact of Long-Term Pretransplant Dialysis Was Not Noted on the Survival of Renal Grafts from DCD Donors
Introduction: Because of worldwide organ shortage, the average waiting period for a cadaveric renal graft is about 15 years in Japan. Therefore, recipients tend to…2013 American Transplant Congress
Role of the Alternative Pathway of Complement in Ischemia/Reperfusion and Chronic Graft Injury in a Mouse Model of Kidney Allograft
Transplant Research Center, Mario Negri Institute, Bergamo, Italy
Several studies suggested that activation of the alternative pathway (AP) of complement participates in kidney ischemia/reperfusion (I/R) injury. In mouse models of renal artery clamping,…2013 American Transplant Congress
Hypoxia Enhances Dendritic Cell Antigen Presentation through the Indirect Pathway
Transplant Research Center, Mario Negri Institute, Bergamo, Italy
Evidence is available that, in kidney transplantation, ischemic injury causes activation of intragraft dendritic cells (DCs), a key event for T cell alloactivation through the…2013 American Transplant Congress
Donor-Specific HLA Antibodies in Crossmatch Negative Renal Transplant Patients Associates with Delayed Graft Function
In kidney transplantation delayed graft function (DGF) is a significant clinical problem affecting the kidney allograft during the whole clinical course. DGF also leads to…2013 American Transplant Congress
Dendritic Cells Phenotype Fitting under Hypoxia or LPS. ABC Transporters Far beyond an Efflux Pump
Nephrology Department, IDIBELL. Hospital Universitari Bellvitge, Barcelona, Spain
This study examines ABC-transporters as a potential therapeutic target in dendritic cell (DC) modulation under hypoxia and LPS. Functional capacity of DCs (mixed lymphocyte reaction,…2013 American Transplant Congress
AMPK Activator Promotes, but Complement and Thrombin Inhibit Anti-A/B Antibody-Induced Accommodation in Endothelial Cells
[Purpose] Several efforts have been made to define the mechanisms of accommodation termed as a condition without graft rejection even in the presence of anti-donor…2013 American Transplant Congress
Early Recurrence of Hepatocellular Carcinoma after Primary Liver Resection Is Associated with Poor Outcome of Salvage Liver Transplantation: A Multicenter Analysis of 82 Cases
Objective) Salvage liver transplantation (LT) is considered a feasible option for treatment of recurrent hepatocellular carcinoma (HCC), especially when living-donor LT is a possible option.…