ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Long-Term Outcomes Following Acute Rejection in Kidney Transplant Recipients: An ANZDATA Analysis

    P. Clayton, S. McDonald, G. Russ, S. Chadban

    Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry, Adelaide, SA, Australia; Department of Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia; Sydney Medical School, University of Sydney, Sydney, NSW, Australia; Faculty of Health Sciences, University of Adelaide, Adelaide, SA, Australia

    Declining rates of acute rejection (AR) and an apparent dissociation between acute rejection incidence and 1 year graft survival have raised questions as to the…
  • 2013 American Transplant Congress

    Rabbit Antithymocyte Globulin Induction Therapy Induces Donor-Specific HeliosnegFOXP3pos Regulatory T Cells in Kidney Transplant Patients

    A. Bouvy, M. Klepper, M. Kho, J. IJzermans, N. Litjens, M. Betjes, W. Weimar, C. Baan

    Internal Medicine, ErasmusMC, University Medical Center, Rotterdam, Netherlands; Surgery, ErasmusMC, University Medical Center, Rotterdam, Netherlands

    Introduction: Repopulation of regulatory T cells (Treg) after rabbit antithymocyte globulin (rATG) induction therapy in kidney transplant patients occurs via either thymopoiesis or homeostatic proliferation.…
  • 2013 American Transplant Congress

    Epidemiology and Prevention Approaches for Cytomegalovirus (CMV) Disease in CMV-Seropositive Kidney Transplant (KT) Recipients: Results from a Multicenter, Prospective, Cohort Study (OPERA Study)

    J. Aguado, M. Fernández-Ruiz, M. Arias, J. Campistol

    Hospital Universitario "12 de Octubre", Madrid, Spain; Hospital Universitario "Marqués de Valdecilla", Santander, Spain; Hospital Clinic, Barcelona, Spain

    Background: Although much is known about the incidence and prevention strategies in CMV-seronegative KT recipients, there is comparatively little information on these issues in CMV-seropositive…
  • 2013 American Transplant Congress

    Impact of Long-Term Pretransplant Dialysis Was Not Noted on the Survival of Renal Grafts from DCD Donors

    M. Takenaka, M. Kusaka, H. Sasaki, Y. Kubota, N. Fukami, R. Shiroki, T. Kenmochi, K. Hoshinaga

    Urology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan; Transplant Surgery, Fujita Health University School of Medicine, Toyoake, Aichi, Japan

    Introduction: Because of worldwide organ shortage, the average waiting period for a cadaveric renal graft is about 15 years in Japan. Therefore, recipients tend to…
  • 2013 American Transplant Congress

    Role of the Alternative Pathway of Complement in Ischemia/Reperfusion and Chronic Graft Injury in a Mouse Model of Kidney Allograft

    R. Cavinato, N. Azzollini, F. Casiraghi, M. Todeschini, S. Aiello, G. Remuzzi, M. Noris

    Transplant Research Center, Mario Negri Institute, Bergamo, Italy

    Several studies suggested that activation of the alternative pathway (AP) of complement participates in kidney ischemia/reperfusion (I/R) injury. In mouse models of renal artery clamping,…
  • 2013 American Transplant Congress

    Hypoxia Enhances Dendritic Cell Antigen Presentation through the Indirect Pathway

    S. Aiello, F. Rocchetta, N. Azzollini, P. Cassis, S. Solini, M. Mister, F. Casiraghi, G. Remuzzi, M. Noris

    Transplant Research Center, Mario Negri Institute, Bergamo, Italy

    Evidence is available that, in kidney transplantation, ischemic injury causes activation of intragraft dendritic cells (DCs), a key event for T cell alloactivation through the…
  • 2013 American Transplant Congress

    Donor-Specific HLA Antibodies in Crossmatch Negative Renal Transplant Patients Associates with Delayed Graft Function

    J. Peräsaari, L. Kyllönen, K. Salmela, J. Merenmies

    Clinical Laboratory, Finnish Red Cross Blood Service, Helsinki, Finland; Renal Transplant Unit, Helsinki Universtity Hospital, Helsinki, Finland; University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland

    In kidney transplantation delayed graft function (DGF) is a significant clinical problem affecting the kidney allograft during the whole clinical course. DGF also leads to…
  • 2013 American Transplant Congress

    Dendritic Cells Phenotype Fitting under Hypoxia or LPS. ABC Transporters Far beyond an Efflux Pump

    N. Lloberas, I. Rama, I. LLaudó, J. Torras, G. Cerezo, M. Franquesa, A. Merino, O. Bestard, J. Cruzado, J. Grinyó

    Nephrology Department, IDIBELL. Hospital Universitari Bellvitge, Barcelona, Spain

    This study examines ABC-transporters as a potential therapeutic target in dendritic cell (DC) modulation under hypoxia and LPS. Functional capacity of DCs (mixed lymphocyte reaction,…
  • 2013 American Transplant Congress

    AMPK Activator Promotes, but Complement and Thrombin Inhibit Anti-A/B Antibody-Induced Accommodation in Endothelial Cells

    K. Iwasaki, Y. Miwa, M. Haneda, T. Kuzuya, H. Ogawa, A. Onishi, T. Kobayashi

    Department of Transplant Immunology, Nagoya University School of Medicine, Nagoya, Japan; Department of Hospital Pharmacy, Nagoya University School of Medicine, Nagoya, Japan; Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan; National Institute of Agrobiological Sciences, Tsukuba, Japan

    [Purpose] Several efforts have been made to define the mechanisms of accommodation termed as a condition without graft rejection even in the presence of anti-donor…
  • 2013 American Transplant Congress

    Early Recurrence of Hepatocellular Carcinoma after Primary Liver Resection Is Associated with Poor Outcome of Salvage Liver Transplantation: A Multicenter Analysis of 82 Cases

    S. Lee, C. Kwon, S. Yang, H. Park, W. Cho, J. Kim, J. Park, S. Kim, J. Joh, B. Kim, H. Wang, K. Lee, K. Suh, S. Lee

    Department of Surgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea; Department of Surgery, Ajou University School of Medicine, Suwon; Department of Surgery, Seoul National University College of Medicine, Seoul, Korea

    Objective) Salvage liver transplantation (LT) is considered a feasible option for treatment of recurrent hepatocellular carcinoma (HCC), especially when living-donor LT is a possible option.…
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