ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Incidence of Malignancy after Kidney Transplantation in the New Era of Immunosuppression

    K. Omoto, T. Shimizu, M. Inui, T. Nozaki, D. Toki, H. Ishida, K. Tanabe

    Department of Urology, Tokyo Women's Medical University, Tokyo, Japan

    Introduction: Transplant recipients have elevated cancer risk, due in part to immunosuppression and infection with oncogenic viruses. Although recent immunosuppressive therapy using basiliximab and rituximab…
  • 2013 American Transplant Congress

    Donor-Derived Strongyloidiasis in Transplant Recipients – United States 2009-2012

    F. Abanyie, E. Bosserman, S. Montgomery, M. Kuehnert, S. Hocevar, P. Chin-Hong

    Centers for Disease Control and Prevention (CDC), Atlanta, GA; UCSF, San Francisco, CA

    Background: Donor-derived Strongyloides stercoralis infection is an emerging public health concern among solid-organ transplant recipients. Immunosuppressed transplant recipients are at risk for hyperinfection syndrome and…
  • 2013 American Transplant Congress

    Do Donor Specific Antibodies Affect Graft Liver Outcomes after Living Donor Liver Transplantation?

    D. Joo, S. Song, S. Lee, M. Kim, A. Lee, J. Choi, S. Kim

    Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea

    Background: Preformed circulating donor specific antibodies (DSAs) immunologically challenge vascular endothelium and the bile duct. However, the liver is an immune tolerant organ and can…
  • 2013 American Transplant Congress

    Graft Infiltrating Foxp3 Tregs in Spontaneously Tolerant Renal A Allografts Express High Levels of CXCR3 and BLIMP-1

    M. Hu, C. Wang, G. Zhang, M. Saito, Y. Wang, M. Fernandez, Y. Qian, Y. Wang, A. Sawyer, W. Hawthorne, C. Jones, T. Sparwasser, A. Bishop, A. Sharland, P. O'Connell, S. Alexander

    CKR, Children's Hospital at Westmaed, Westmead, Australia; CTRR, Westmead Millennium Institute, University of Sydney, Wesmead, Australia; CTL, Royal Prince Alfred Hospital, Sydney, Australia; CPIR, Children's Hospital at Westmead, Westmead, Australia; Institute of Infection Immunology, Centre for Experimental and Clinical Infection Research, GmbH, Hanover, Germany

    Background: Foxp3+Tregs have an essential role in allograft tolerance. Aim: To evaluate Foxp3+Tregs in the spontaneous tolerance of mouse renal allografts. Methods: A standard mouse…
  • 2013 American Transplant Congress

    MicroRNAs (miRNAs) Identified in Human Formalin-Fixed Paraffin-Embedded (FFPE) Kidney Biopsies Regulate Acute Cellular Rejection (ACR) and Renal Allograft Functional Status

    P. Ruiz, E. Margolles-Clark, J. Sageshima, G. Ciancio, L. Chen, A. Mattiazi, G. Guerra, W. Kupin, D. Roth, G. Burke

    Surgery, University of Miami, Miami, FL; Medicine, University of Miami, Miami, FL

    Alterations of miRNA expression regulate the post-transcriptional expression of many target genes in allografts and thus likely help regulate alloreactive processes. We carried out a…
  • 2013 American Transplant Congress

    Comparison of Pediatric En-Bloc Renal Allograft Growth and Function for Donors Less Than One Year of Age with Older Pediatric Donors

    N. Rowe, M. Dion, J. Shum, C. Weernink, A. Sener, P. Luke

    Urology, Western University, London, ON, Canada

    Introduction: The use of pediatric en-bloc kidneys obtained from infant donors of very small size has previously been investigated. Some transplantation centers have under-utilized very…
  • 2013 American Transplant Congress

    Comparison of Estimated Glomerular Filtration Rate Using Cystatin C Versus Creatinine in Pediatric Renal Transplant Patients

    H. Pizzo, J. Nguyen, G. Schwartz, R. Ettenger, E. Tsai

    Pediatric Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA; Pediatric Nephrology, University of Rochester School of Medicine, Rochester, NY

    Purpose: Analyze the accuracy of estimated glomerular filtration rate (eGFR) in pediatric renal transplant (Tx) patients (pts) using cystatin C, serum creatinine (SCr), and the…
  • 2013 American Transplant Congress

    Increased Duration of Dual Pegylated Interferon and Ribavirin Therapy for Genotype 1 Hepatitis C Post-Liver Transplantation Increases Sustained Virologic Response: A Retrospective Review

    M. Wells, P. Marotta, M. Levstik, N. Chandok, L. Roth, V. Bain, A. Mason, B. Aljudaibi

    Department of Gastroenterology and Hepatology, Western University, London, ON, Canada; General Division, The Scarborough Hospital, Scarborough, ON, Canada; University of Alberta, Edmonton, AB, Canada

    Aims: Hepatitis C–related cirrhosis is the leading indication for liver transplantation. HCV recurrence is almost universal, leading to advanced fibrosis in at least 30% of…
  • 2013 American Transplant Congress

    Graft Function Measured by Transient Elastography in Living Donor Liver Transplantation: Preliminary Results

    S. Lee, D. Joo, S. Kim, M. Kim, A. Lee, G. Choi, J. Choi, K. Han, S. Kim

    Department of Surgery, Yonsei University College of Medicine; Research Institute for Transplantation, ; Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea

    Introduction: Liver stiffness (LS) measurement using transient elastography (TE) provide a non-invasive means of assessing liver fibrosis and are correlated to hepatic cholestasis. However, few…
  • 2013 American Transplant Congress

    Divided Daily Prednisolone Dosing Reduces Hyperglycemia after Kidney Transplantation

    S. Cohney, S. Fourlanos, P. Colman, C. Yates

    Medicine, University of Melbourne, Melbourne, Victoria, Australia; Nephrology, Western Hospital, Melbourne, Victoria, Australia; Epidemiology and Preventative Medicine, Monash University, Melbourne, Victoria, Australia; Diabetes and Endocrinology, Royal Melbourne Hospital, Melbourne, Victoria, Australia

    The pharmacokinetics of prednisolone indicate that divided twice daily (BD) dosing would produce more even drug exposure and may improve glycemia compared with daily (QD)…
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