2013 American Transplant Congress
Complement-Activating DSA: Which Assay in Which Setting?
Imperial College Renal & Transplant Centre, Hammersmith Hospital, London, United Kingdom
The presence of pre-formed and de novo donor specific antibodies [DSA] are associated with an increased incidence of antibody mediated rejection [AMR] and graft loss…2013 American Transplant Congress
Complement-Activating Low-Level Preformed Donor-Specific Antibodies Detected by C1qScreen™ Predict Early Antibody-Mediated Rejection in Renal Allografts
Imperial College Renal & Transplant Centre, Hammermsith Hospital, London, United Kingdom
Renal transplant recipients with negative CDC [CDC-XM] and Flow crossmatch [Flow-XM] and low level DSA [by Luminex] have worse outcomes than non-sensitized patients. The aim…2013 American Transplant Congress
In-Vivo Persistence, Trafficking and Phenotypic Stability of Autologous, Ex-Vivo Expanded Rhesus Macaque Natural Regulatory T Cells
Emory Univ, Atlanta; Univ of Minnesota, Minneapolis
Infusion of ex-vivo expanded natural regulatory T cells (Tregs) is emerging as a promising cellular therapy for the induction of allograft tolerance. However, the lack…2013 American Transplant Congress
Liver Transplantation for Neonatal Hemochromatosis: Analysis of the UNOS Database
Neonatal hemochromatosis (NH) is a rare condition of unclear etiology and remains the most common identifiable cause of acute liver failure in the neonate. Liver…2013 American Transplant Congress
Renal Ischemia/Reperfusion Induces Release of Angiopoietin-2 from Human Grafts of Living and Deceased Donors
Recent insights suggest that endothelial cell (EC) activation plays a major role in renal ischemia/reperfusion (I/R) injury. Interactions between ECs and pericytes via signaling molecules,…2013 American Transplant Congress
Predictors of Combined Liver and Kidney Transplantation and Post-Transplant Liver Graft, Kidney Graft, and Patient Survival: Comparison to Patients Receiving Listed for Kidney but Receiving Liver Alone
Background: Data on patient and liver kidney graft survival following combined liver kidney (CLK) transplantation remain conflicting. Aim: To compare outcomes after CLK transplantation to…2013 American Transplant Congress
Factors Influencing Creatinine Rise Following Donor Nephrectomy
Kidney and Pancreas Transplantation, Vanderbilt University, Nashville, TN
Introduction: Identifying factors influencing the rise in creatinine following donor nephrectomy will permit appropriate candidate selection and help ensure the long term safety of live…2013 American Transplant Congress
Determinants of Geographic Variation in Access to Deceased Donor Kidney Transplantation for Children
University of Pennsylvania, Philadelphia, PA; Children's Hosp of Philadelphia, Philadelphia, PA
The OPTN prioritizes pediatric candidates (<18 years) in kidney allocation because children derive unique benefits from kidney transplant (KT). However, because allocation usually starts locally,…2013 American Transplant Congress
Gender Disparity in Attitudes of Older Adults towards Kidney Transplantation
Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD
Purpose: Elderly women with ESRD are significantly less likely than men of the same age and co-morbidities to be referred for kidney transplantation (KT), despite…2013 American Transplant Congress
Insulin-Like Growth Factor-II (IGF-II) Prevents Pro-Inflammatory Cytokine Induced Apoptosis and Significantly Improves Islet Survival Post-Transplantation
Introduction: The early loss of functional islet mass (50-70%) due to apoptosis following clinical transplantation contributes to islet allograft failure. Insulin-like Growth Factor-II (IGF-II) is…