2013 American Transplant Congress
Ex-Vivo Generation of Immunosuppressive Human Cells by Co-Culture of Recipient and Irradiated Donor PBMCs under CD80/CD86 Costimulation Blockade
Purpose:We have shown that co-culture of recipient and irradiated donor splenocytes under presence of anti-CD80 and anti-CD86 mAbs generates immunosuppressive cells in-culture and induces tolerance…2013 American Transplant Congress
Influence of Baseline Immunosuppresion on Renal Function and Clinical Outcomes in Liver Transplantation, The
Pharmacy, MUSC, Charleston, SC; Surgery, MUSC, Charleston, SC
Background: Preserving renal function in liver transplantation has become paramount to improving long-term survival. However, there are limited definitive studies comparing different immunosuppression (IS) regimens…2013 American Transplant Congress
Portrait of CAD with IF-TA Development Post Kidney Transplantation. Proteomics as Noninvasive Biomarkers
UVA, Charlottesville; VCU, Richmond
Background: Chronic allograft dysfunction (CAD) with interstitial fibrosis-tubular atrophy (IFTA) post kidney transplantation (KT) is one of the most common causes of graft loss. This…2013 American Transplant Congress
Regulatory Molecular Profile of Early Ischemia Reperfusion Injury after Liver Transplantation
UVA, Charlottesville; VCU, Richmond
Background: Graft function post liver transplantation (LT) depends on donor quality and the degree of hepatocyte post-ischemia reperfusion injury (IRI). Hereby, we evaluated early-deregulated molecular…2013 American Transplant Congress
Potential Contributions to the Direct Pathway by Donor Dendritic Cells at Vascularized Graft
It is widely known that resident dendritic cells (DC) in tissue, or donor DC (dDC), are able to traffic to the secondary lymphoid tissues of…2013 American Transplant Congress
Regulatory Effect of microRNAs in Ischemia Reperfusion Injury Post Liver Transplantation: Looking for Therapeutic Targets
Background: MicroRNAs (miRNA) exert regulatory effects in biological mechanisms and had been recently targeted for therapeutic interventions. In Liver Transplantation (LT), graft function post reperfusion…2013 American Transplant Congress
Genomic-Derived Markers for Early Detection of Calcineurin Inhibitor Toxicity Post-Kidney Transplantation: Contribution to Chronic Allograft Dysfunction Progression
UVA, Charlottesville; VCU, Richmond
Background. Use of calcineurin inhibitors (CNIs) after kidney transplantation (KT) induces vasoconstriction of renal afferent arterioles, leading to functional changes and potentially irreversible chronic ischemic…2013 American Transplant Congress
Non-Alcoholic Fatty Liver Disease (NAFLD) Epidemic and Its Implications for Liver Transplantation
Tampa General Medical Group, Tampa, FL
NAFLD is increasingly recognized as the most common chronic liver disease in the western world. With the increasing prevalence of the risk factors of NAFLD…2013 American Transplant Congress
Acute Kidney Injury in Kidney Transplant Patients According to the Rifle and Akin Criteria
Renal Transplantation, Albert Einstein Israelita Hospital, São Paulo, Brazil
A. PurposeTo assess the incidence, risk factors and outcomes associated with acute kidney injury (AKI) in kidney transplant in-patients using RIFLE (R-risk, I-Injury, F-failure, L-loss,…2013 American Transplant Congress
Energy Status of Pig Donor Organs after Ischemia Is Independent of Donor Type
Background. Literature is controversial whether organs from living donors have a better graft function than brain dead and non-heart-beating donor organs. Success of transplantation has…