Abstracts Archive - Page 156 of 1683 - ATC Abstracts

2022 American Transplant Congress
Characterization of Hepatocytes During Cold Static Preservation at Single Cell Resolution
S. Naik¹, M. Dogan¹, C. Watkins¹, A. Bajwa¹, C. Eymard², J. Eason³, C. Kuscu¹, C. Kuscu¹
¹Transplant Research Institute, James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, ²James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, ³University of Tennessee/Methodist Transplant Institute, Memphis, TN
*Purpose: Hepatocytes together with liver sinusoidal endothelial cells (LSEC) are the most affected cells during cold preservation of donor liver. Necrotic and apoptotic hepatocytes release…
2022 American Transplant Congress
Immunotherapy Before Solid Organ Transplantation: An International Transplant Community-Focused Survey
T. Ivanics¹, M. P. Claasen¹, D. Al-Adra², G. Sapisochin³
¹University of Toronto - University Health Network, Toronto, ON, Canada, ²Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, ³Multi-organ transplant program, University Health Network, Toronto, ON, Canada
*Purpose: The use of immunotherapy for cancer has increased and is expected to continue to grow. The outcomes after solid organ transplantation (SOT) in patients…
2022 American Transplant Congress
Evs from Patients with Amr Induce Tubular Senescence and Endmt Through Horizontal Transfer of Mirnas
R. Franzin¹, A. Stasi¹, F. Sallustio¹, S. Bruno², G. Merlotti³, M. Quaglia³, G. Grandaliano⁴, P. Pontrelli¹, J. Thurman⁵, G. Camussi², G. Stallone⁶, V. Cantaluppi³, L. Gesualdo¹, G. Castellano⁷
¹DETO, University of Bari, Bari, Italy, ²University of Turin, Turin, Italy, ³University of Piemonte Orientale, Novara, Italy, ⁴Università Cattolica Sacro Cuore, Rome, Italy, ⁵University of Colorado School of Medicine, Aurora, CO, ⁶University of Foggia, Foggia, Italy, ⁷University of Milan, Milan, Italy
*Purpose: Extracellular vesicles (EV) are emerging mediators in several diseases; however, their role in antibody-mediated allograft rejection (AMR) has been poorly investigated.*Methods: Plasma EVs from…
2022 American Transplant Congress
Bariatric Surgery and Alcohol Related Steatohepatitis (BASH): An Increasing Etiology in Pre-Liver Transplant Candidates
S. Nishida¹, K. Okumura¹, A. Dhand², R. Bodin², S. Yaghoubian³, C. Greenberg¹, R. Misawa¹, G. Veillette¹, H. Sogawa¹, D. John¹, D. C. Wolf², B. Partiula², T. Diflo¹, R. Latifi¹, S. Lansman¹
¹Surgery, Westchester Medical Center/ New York Medical College, Valhalla, NY, ²Medicine, Westchester Medical Center/ New York Medical College, Valhalla, NY, ³Anesthesia, Westchester Medical Center/ New York Medical College, Valhalla, NY
*Purpose: Obesity-related fatty liver disease and non-alcoholic steatohepatitis (NASH) are common causes of End-stage liver disease (ESLD). Bariatric surgery (BS) is commonly indicated for these…
2022 American Transplant Congress
A Sustained Injury Response by Regulatory T Cells (Treg) Contributes to Fibrosis to Promote Chronic Rejection After Heart Transplantation
J. Bou Saba¹, L. Fan¹, X. Zhang¹, T. Li¹, L. R. Mathews¹, G. Dwyer², E. Colon², M. J. Calderon³, K. E. Helfrich³, M. A. Ross³, S. C. Watkins³, H. Turnquist¹
¹Surgery, University of Pittsburgh, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, ²Immunology, University of Pittsburgh, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, ³Cell Biology, University of Pittsburgh, Center for Biologic Imaging, Pittsburgh, PA
*Purpose: Chronic rejection (CR) results from the development of immunosuppressant-resistant allograft vasculopathy and fibrosis and remains a leading cause of recipient death one-year post-heart transplant…
2022 American Transplant Congress
The Ties That Transplant: The Social Network Determinants of the Living Kidney Donor Relationship Distribution
J. Daw
Sociology & Criminology, The Pennsylvania State University, University Park, PA
*Purpose: To describe and explain the distribution of social relationships of living kidney donors to kidney transplant recipients.*Methods: Using an original dataset of transplant candidates…
2022 American Transplant Congress
Pretransplant Transcriptome Predicts 24-Month Kidney Function
E. Bardhi¹, K. Archer², D. Maluf¹, J. McDaniels¹, T. Rousselle¹, E. Akalin³, T. Mueller⁴, V. Mas¹
¹University of Maryland School of Medicine, Baltimore, MD, ²Ohio State University, Columbus, OH, ³Montefiore Medical Center, Bronx, NY, ⁴Universityspital Zurich, Zurich, Switzerland
*Purpose: With the development of novel prognostic tools derived from omics technologies, transplant medicine is entering the era of precision medicine, however, there are no…
2022 American Transplant Congress
Lipid Metabolism Profile of Human Kidneys During Ex Vivo Normothermic Perfusion
J. Yu, I. Palma, S. Adams, J. Sageshima, P. Than, R. Perez
UC Davis Medical Center, Sacramento, CA
*Purpose: The kidney is a highly metabolic organ and lipids are an important energy source. In this study, we examined the lipid profiles of discarded…
2022 American Transplant Congress
Impact of Mycetoma in Lung Transplant Recipients
A. Majeed, S. Singh, J. Lum
CCF, Cleveland, OH
*Purpose: Mycetoma are uncommon in lung transplant recipients (LTRs) and previous studies describe poor outcomes. We reviewed our experience*Methods: Retrospective review of electronic medical records…
2022 American Transplant Congress
Oseltamivir for the Prevention of Influenza Infection in Lung Transplant Recipients at an Academic Medical Center
D. Majmundar, A. Mishkin, J. Burnell, C. Ruggia-Check, J. Au
Temple University Hospital, Philadelphia, PA
*Purpose: Influenza is commonly considered a community acquired infection, but in transplant recipients, nosocomial transmission is frequently encountered. The lung transplant program at Temple University…