2022 American Transplant Congress
Depletion of Donor Macrophages Permits Post-Transplant Tolerance Induction
*Purpose: Using donor splenocytes fixed with cross-linker ethylcarbodiimide (ECDI-SPs), our lab has induced tolerance in a variety of murine and non-human primate models when one…2022 American Transplant Congress
Role of Group 2 Innate Lymphoid Cells in Murine Heart Transplant
*Purpose: Group 2 innate lymphoid cells (ILC2s) have been shown to play key roles in manipulating adaptive immunity. They regulate CD4+ T cell biology not…2022 American Transplant Congress
Batf3 and IRF4 in Control of iTreg Differentiation, Stability, and Survival
Houston Methodist Research Institute, Houston, TX
*Purpose: The use of in vitro-differentiated induced Tregs (iTregs) in transplantation and various diseases is a promising therapeutic that is limited by challenges to iTreg…2022 American Transplant Congress
Biopsy and Blood Gene Expression Profiles Distinguish Injury, Subclinical and Clinical Rejection in Kidney Transplant Recipients
1Scripps Health, La Jolla, CA, 2Northwestern University, Chicago, IL
*Purpose: We analyzed serial gene expression profiles in paired blood and biopsies from kidney transplant recipients phenotyped with a comprehensive clinical algorithm. We compared disease…2022 American Transplant Congress
Leflunomide in Children with BK Polyomavirus Viremia After Kidney Transplant
1The Children's Hospital of Philadelphia, Philadelphia, PA, 2Yale New Haven Health, New Haven, CT
*Purpose: Studies examining the use of leflunomide in treating BK polyomavirus (BKPyV) viremia in children after kidney transplant are limited to case reports with small…2022 American Transplant Congress
Baseline Predictors of Antimicrobial Utilization in Solid Organ Transplant Recipients
*Purpose: Antimicrobial use (AU) is a major driver of antimicrobial resistance but is understudied in solid organ transplant (SOT) recipients. Our study sought to quantify…2022 American Transplant Congress
De Novo Anti-Brush Border Antibody Disease in a Kidney Transplant Recipient
Ohio State University, Columbus, OH
*Purpose: Anti-brush border antibody (ABBA) disease is very rare, characterized by tubulointerstitial damage caused by autoantibodies against LDL receptor-related protein 2 (LRP2) in the proximal…2022 American Transplant Congress
Programmatic Fidelity is Central to the Development of Virtual Living Donor Kidney Transplantation Educational Programs
University of Alabama at Birmingham, Birmingham, AL
*Purpose: The Living Donor Navigator program is designed to mitigate disparities in living donor kidney transplantation (LDKT), though geographic disparities in program participation were observed…2022 American Transplant Congress
Impact of Respiratory Viral Panel Testing on Clinical Decision-Making Among Lung Transplant Recipients Based on Extent of Immunosuppression
*Purpose: Lung transplant recipients (LTRs) are at high risk for complications from viral respiratory infection, including chronic allograft dysfunction. Thus, multiplex molecular testing for respiratory…2022 American Transplant Congress
Low-Dose Aspirin is More Critical Than Statins in Preventing Transplant Renal Artery Stenosis
Urology, Henan Provincial People's Hospital, Zhengzhou, China
*Purpose: To explore the clinical value of low-dose aspirin (100mg) and statins (10 ~ 20mg) in the prevention of transplant renal artery stenosis (TRAS).*Methods: A…
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