2013 American Transplant Congress
Effect of Human Adipose Derive Mesenchymal Stem Cells on Liver Ischemia-Reperfusion Injury and Regeneration in Humanized Mice, The
University of Massachusetts, Worcester
Liver ischemia-reperfusion injury (IRI) is a well-known cause of morbidity and mortality following Liver transplantation. Effective treatment strategies aimed at reducing hepatic IRI injury and…2013 American Transplant Congress
Distal Splenorenal Shunt (DSRS) in the Modern Era of Liver Transplantation
Transplantation and Hepatobiliary Diseases, Lahey Clinic Medical Center, Burlington, MA
Background: DSRS is a "selective" shunt used to treat bleeding complications of portal hypertension and has the advantage of long-term patency, low rebleeding and encephalopathy…2013 American Transplant Congress
Selective Blockade of VLA-4 Integrin Inhibits Early Infiltration of Endogenous Memory CD8 T into Cardiac Allograft and Donor-Reactive T Cell Priming
Immunology, Cleveland Clinic, Cleveland, OH; Urology, Tokyo Women's Medical Univ, Tokyo, Japan
INTRODUCTION: We recently reported that endogenous memory CD8 T cells infiltrate MHC-mismatched cardiac allografts and produce IFN-Γ in response to donor class I MHC molecules…2013 American Transplant Congress
Anti-Perlecan Antibodies Are Novel Accelerators of Immune-Mediated Vascular Injury
Acute vascular rejection (AVR) is characterized by immune-mediated vascular injury and heightened endothelial cell (EC) apoptosis. We previously reported that apoptotic ECs release a bioactive…2013 American Transplant Congress
Inherited Patients: Friend or Foe?
The Purpose of our study was to investigate the role of inherited patients in transplant centers. For the purpose of this study, an inherited patient…2013 American Transplant Congress
Effect of ASP0028 in Combination with Tacrolimus on Kidney Transplantation in Cynomolgus Monkeys, The
Introduction: Sphingosine 1-phosphate (S1P) is a bioactive lipid mediator involved in many critical physiological processes including immunity. ASP0028 is a recent developed S1P1/S1P5 selective agonist.…2013 American Transplant Congress
Pretransplant Infusion of Donor Stem Cells Open Gateway to Tolerance through Induction of Regulatory T Cells and Activation of Other Allosuppressive Immune Mechanisms – Single Centre Experience in Living Donor Renal Transplantation
Introduction: Data regarding stem cell infusion (SCI) for tolerance induction in renal transplantation (RTx) is sparse. We designed a prospective trial in a cohort of…2013 American Transplant Congress
Sequential Analysis of Donor-Specific Antibodies and Pathological Findings in Acute Antibody-Mediated Rejection: A Rat Renal Transplantation Model
Background. Although clinical evidence regarding antibody- and complement-mediated injury in renal transplantation is available, the mechanism of acute antibody mediated rejection, AAMR, remains unclear. Therefore,…2013 American Transplant Congress
Pharmacokinetics and CYP3A5 Pharmacogenetics for Once- Versus Twice-Daily Tacrolimus from First Dosing Day to 1 Year Post-Transplantation
Backgrounds: Tacrolimus is available as an immediate-release, twice-daily formulation (Tac-BID), and a prolonged-release once-daily formulation (Tac-QD). A number of studies found that the daily dose…2013 American Transplant Congress
Retroperitoneoscopic Living Donor Nephrectomy Safely Provides Excellent Graft Function
BACKGROUND: Laparoscopic living donor nephrectomy has been a standard procedure of donor nephrectomy. The transperitoneal hand-assisted laparoscopic living donor nephrectomy (HALDN) has been commonly reported…
American Transplant Congress abstracts