2013 American Transplant Congress
Effects of the Novel PKCθ Selective Inhibitor AS2521780 on Acute Rejection in Rats and Monkeys
BackgroundInhibition of T-cell activation is the most effective to prevent acute cellular rejection. Protein kinase C (PKC) theta is a crucial signaling enzyme in the…2013 American Transplant Congress
Donor Hepatitis C Status Does Not Impact Outcomes in Hepatitis C Positive Kidney Transplant Recipients
Background:The kidneys from HCV positive donors remain to be underutilized, as there are multiple studies which have shown reduced patient and graft survival rates among…2013 American Transplant Congress
Deletion of CD98hc in Lymphocytes Results in Increasing Treg Cell To Prevent Acute Murine GvHD
CD98 heavy chain (CD98hc), encoded by Slc3a2, is a widely expressed vertebrate membrane protein whose functions are known as facilitating amino acid transporter and mediating…2013 American Transplant Congress
Modulation of Allogeneic CD8+ T Cell Response by Histone Methylation Inhibitor DZNep Can Control GVHD While Preserving Hematopoietic Chimerism
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) following solid-organ transplantation is a feasible method to achieve long-lasting organ allograft tolerance through the induction of hematopoietic chimerism…2013 American Transplant Congress
Assessment of Vitamin D and Changes in Bone Mineral Density in a Predominantly African American Pediatric Kidney Transplant Population
Children's National, Washington, DC
Purpose The purpose of this study was to investigate nutritional Vitamin D (Vit D) deficiency and changes in bone mineral density (BMD) over 1 year…2013 American Transplant Congress
Risk of Recurrence of Pre-Existing Cancer in Organ Recipients
A past history of cancer is a relative contraindication to undergoing organ transplantation because of the risk of recurrence of cancer. However, the extent of…2013 American Transplant Congress
Health-Related Quality of Life (HRQOL) of Recipients after Living-Donor Liver Transplantation (LDLT)
With the improvement of patient survival after living-donor liver transplantation (LDLT), not only a simple survey of mortality and morbidity but also health-related quality of…2013 American Transplant Congress
HLA-Antigens as a Risk Factor in Polyomavirus BK Viremia
Identification of HLA-antigens that modulate immunity to polyomavirus BK (BKV) infection could be used to (a) fine tune virus screening strategies in individual patients, and…2013 American Transplant Congress
Alloimmune and Non-Alloimmune Kidney Graft Losses, Improving Our Understanding of Factors Associated with Failure
Introduction. Death-censored graft loss (GL) is generally analyzed as a single endpoint. However, GL has multiple causes, alloimmune (GLA, acute rejection, chronic antibody rejection) and…2013 American Transplant Congress
Critical Role of Allograft Infiltrating ROR Gamma t Positive Innate Immune Cells and Hematopoietic Progenitor Cells
Using a minimally invasive in vivo imaging system to serially monitor fluorescence emitting T cell subtypes infiltrating islet allografts, we have now probed for the…
American Transplant Congress abstracts