2022 American Transplant Congress
Longitudinal Analysis of Donor-Derived Cell-Free DNA (dd-cfDNA) in En-Bloc Kidney Transplantation
*Purpose: The longitudinal dd-cfDNA patterns in en-bloc kidney transplant recipients have not been studied. It is unknown how the initial smaller mass of the two…2022 American Transplant Congress
Factors Linked with Evaluation to Wait Listing for Referred Patients at the University of Texas Medical Branch’s Main Center and Outreach Clinic – A Step Towards Kidney Transplantation
*Purpose: Numerous factors can be associated with transplant candidates’ placement on the wait list. We herein set forth to assess patient characteristics and factors associated…2022 American Transplant Congress
Belatacept Augments Mixed Chimerism in a Novel Nonhuman Primate Kidney Transplant Tolerance Induction Protocol
University of Wisconsin, Madison, WI
*Purpose: A novel protocol of antilymphocyte globulin (ATG), tomotherapy-based total lymphoid irradiation (TomoTLI), and adoptive cellular transfer was developed in a preclinical model of MHC-mismatched…2022 American Transplant Congress
Textbook Outcome in Lung Transplantation: Planned VA ECMO versus Off-Pump
*Purpose: Planned venoarterial extracorporeal membrane oxygenation (VA ECMO) is increasingly used during bilateral orthotopic lung transplantation (BOLT) and may be superior to off-pump (OP) support…2022 American Transplant Congress
PFIC- Outcome and Time to Transplant After Biliary Diversion According to Genetic Subtypes
*Purpose: Progressive familial intrahepatic Cholestasis (PFIC) is a heterogeneous autosomal recessive disease characterized by progressive cholestasis, pruritus leading to liver injury. Surgical therapy aims in…2022 American Transplant Congress
Alloprimed Antibody-Suppressor CD8+ T Cells Preferentially Kill Alloprimed Germinal Center B Cells
*Purpose: Antibody-mediated rejection (AMR) is a significant contributor to transplant rejection. Our prior work identified a novel subset of CXCR5+CD8+ T cells (CD8+ TAb-supp cells)…2022 American Transplant Congress
‘Adjuvant Conditioned’ Myeloid Derived Suppressor Cells Prolong Islets Graft Survival Through IL-10 Production
*Purpose: Advances in immunosuppression have been relatively stagnant over the last 2 decades and transplant patients continue to experience morbidity associated with immunosuppression regimens. Through…2022 American Transplant Congress
Differences of Fk-Binding Protein 12 and P-Glycoprotein Explain the Differences in the Intracellular Tacrolimus Concentration of T Lymphocytes and Monocytes
Erasmus MC, Rotterdam, Netherlands
*Purpose: Little is known about the pharmacokinetics of intracellular tacrolimus, particularly in T lymphocytes and monocytes. We demonstrated a significantly lower intracellular tacrolimus concentration in…2022 American Transplant Congress
Desensitization Using Costimulatory Blockade and Bortezomib to Prevent DSA Formation and Rejection in Reconstructive Transplantation
Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: Sensitization in form of donor-specific antibodies (DSA) and subsequent antibody-mediated rejection constitute some of the greatest risk factors for allograft rejection and long-term graft…2022 American Transplant Congress
Early Evaluation Of The Impact Of Change In UNet Organ Refusal Code Reasons On Us Transplant Center Organ Offers
*Purpose: On December 2, 2021 a new set of organ refusal codes was implemented in DonorNet. These new codes were meant to provide more relevant…
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