ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Single-Cell Multiomics Defines Tolerogenic Extrathymic Aire-Expressing Cells

    A. R. Gupta1, J. Wang2, C. Lareau3, I. Sun2, J. Bautista1, J. Gardner1

    1Department of Surgery, University of California San Francisco, San Francisco, CA, 2Diabetes Center, University of California San Francisco, San Francisco, CA, 3Department of Pathology, Stanford University, Stanford, CA

    *Purpose: The Autoimmune Regulator (Aire) gene, essential for central tolerance through its regulation of tissue-specific antigens in medullary thymic epithelial cells, is also expressed in…
  • 2022 American Transplant Congress

    Effectiveness of a Targeted Media Campaign on Engagement and Interest in Living Donation

    L. A. Davis1, A. Livingston2, A. Waterman3

    1Houston Methodist Hospital, J.C. Walter Jr Transplant Center, Houston, TX, 2Multiview, Irving, TX, 3Transplant Research and Education Center, Houston, TX

    *Purpose: Living donation rates have continued to decline. Research has suggested that disseminating living donation education and information more broadly to larger audiences outside of…
  • 2022 American Transplant Congress

    Robotic-Assisted Reconstruction of the Transplant Ureter: A Minimally Invasive Option for a Rare Complication

    A. Popovic1, M. Hanlon2, S. Iskhagi2, R. Saidi2, S. Blakely3, R. Shahbazov2

    1Urology, Upstate Medical University, Syracuse, NY, 2Surgery, Division of Transplantation, SUNY, Upstate Medical University, Syracuse, NY, 3Urology, SUNY, Upstate Medical University, Syracuse, NY

    *Purpose: Ureteric stricture are rare after kidney transplants but nonetheless this complication requires reconstruction in the majority of cases to avoid graft dysfunction and/or failure.…
  • 2022 American Transplant Congress

    Pretransplant microRNAs in Liver Perfusate Associate with Early Allograft Dysfunction

    E. Bardhi, E. Williams, J. McDaniels, T. Rousselle, V. Mas, D. Maluf

    University of Maryland School of Medicine, Baltimore, MD

    *Purpose: Early allograft dysfunction (EAD) in liver transplantation (LT) is associated with poor long-term graft and patient survival. Prior to LT, while organs are stored…
  • 2022 American Transplant Congress

    Membrane Attack Complex as a More Sensitive Tool to Evaluate Complement Activation in Kidney Transplant Recipients with Donor-Specific Antibodies

    C. Arias-Cabrales, D. Redondo-Pachón, E. Rodríguez, M. Riera, A. Buxeda, M. Pérez-Sáez, C. Burballa, L. Llinas, J. Pascual, M. Crespo

    Nephrology, Hospital del Mar, Barcelona, Spain

    *Purpose: Kidney transplant recipients with late HLA donor-specific antibodies (DSA) detected with single antigen beads (SAB) exhibit more frequent antibody-mediated rejection (ABMR) and graft loss.…
  • 2022 American Transplant Congress

    Non-Invasive Metabolite-Based Urine Signature Detects Over-Immunosuppression in Renal Transplant Recipients

    S. Raghavendra Rao1, C. Honrao1, L. O. Rodrigues1, C. Dong1, K. Sonkar1, J. Wolf1, E. M. O'Day1, D. R. Kuypers2

    1Olaris, Inc., Framingham, MA, 2Department of Nephrology and Renal Transplantation, University Hospitals, Leuven, Belgium

    *Purpose: Managing complications related to over-immunosuppression represents a growing challenge in post-transplant care, with infections accounting for the second leading cause of death with functioning…
  • 2022 American Transplant Congress

    Single Dose Alemtuzemab Provides Comparable Rejection Free and Infection Free Survival Compared to Double Dose Alemtuzumab. In Comparison to Alemtuzemab, Basiliximab Has Superior Infection Free Graft Survival. Results from a Steroid Sparing Transplant Group

    H. Sharma, A. Odugoudar, B. Devkaran, A. Rao, A. El-Bakry, T. Gunawardhane, D. Ridgway, M. Howse, S. Mehra

    Department of Transplant Surgery, Royal Liverpool University Hospital, Liverpool, United Kingdom

    *Purpose: The present study investigated the short-term biopsy-proven acute rejection rates and viral infection rates amongst our protocol of single-dose Alemtuzemab (Cohort 1) versus double…
  • 2022 American Transplant Congress

    Non-HLA Autoantibodies: The Hidden Offenders to Double the Trouble

    R. Naik1, W. Dabbas1, I. Tang2, J. Almario3, Z. Hajjiri1

    1Transplant Nephrology, University of Illinois Chicago, Chicago, IL, 2University of Illinois Chicago, Chicago, IL, 3Transplant Surgery, University of Illinois Chicago, Chicago, IL

    *Purpose: There is emerging evidence suggesting non-HLA autoantibodies triggered after the graft injury. Here, we report 3 cases where non-HLA autoantibodies were positive after 3…
  • 2022 American Transplant Congress

    The Higher Cost of Donation After Circulatory Death Liver Transplantation Starts with Acquisition Costs: A Single Center Comparison Liver Acquisition Fees by Donor Type

    V. Reddy1, S. Asrani2, J. Trotter2, R. Ruiz3, S. Lee2, E. Martinez2, N. Onaca2, G. McKenna4, A. Gupta2, H. Fernandez2, J. Bayer2, G. Testa2, A. Wall2

    1Baylor Scott and White Research Institute, Allen, TX, 2Baylor University Medical Center, Dallas, TX, 3Baylor University Medical Center, Fort Worth, TX, 4Baylor Simmons Transplant Inst, Dallas, TX

    *Purpose: Donation after circulatory death (DCD) donors are an increasing proportion of deceased donor population in the US. One drawback of DCD donors is that…
  • 2022 American Transplant Congress

    Evaluation of Voriconazole Dosing for Preventing Aspergillus in Lung Transplant Recipients

    A. Chaplain1, B. J. Pierce1, C. Pham1, A. Hutchins1, W. L. Musick1, D. T. Nguyen2, E. A. Graviss2, S. W. Yau3, J. G. Youssef3, A. Goodarzi3, H. J. Huang3

    1Pharmacy, Houston Methodist Hospital, Houston, TX, 2Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, 3Medicine, Houston Methodist Hospital, Houston, TX

    *Purpose: We sought to evaluate the efficacy of voriconazole (VCZ) 200 mg twice a day (BID) for 3 months post lung transplant (LT) in preventing…
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