ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Lipocalin-2 in Serum Samples of Recipients Following Liver Transplantation as Predictive and Monitoring Marker for Acute Allograft Rejection

    N. Vallant, H. Maier, M. Kofler, P. Schumpp, S. Schneeberger, R. Oellinger, J. Pratschke, F. Aigner

    Department of Visceral,- Thoracic- and Transplant Surgery, Medical University, Innsbruck, Tyrol, Austria

    PURPOSE: Lipocalin-2 (Lcn-2) has been described as a marker and modulator of inflammation during ischemia/reperfusion injury (IRI) following solid organ transplantation. Aim of this study…
  • 2013 American Transplant Congress

    Correlation of Global Copy Number Changes with Micro RNA Expression Profiling Reveals MUC1 as a Marker for HCC Recurrence after Transplant

    C. Barry, C. Whitney-Miller, M. Orloff

    Transplant Surgery, University of Rochester, Rochester, NY; Pathology, University of Rochester, Rochester, NY

    INTRODUCTION: Epigenetic changes are known to play a pivotal role in hepatocellular carcinogenesis, but the effects of these changes on cancer cell protein expression remain…
  • 2013 American Transplant Congress

    Retransplantation with or without Graft Nephrectomy. A Single Centre Experience

    C. Puliatti, E. Giorgakis, A. Syed

    Renal Transplantation, Royal London Hospital, London, United Kingdom

    Introduction:This study aims to review the impact of nephrectomy of a failed primary allograft on the graft survival of renal retransplantation.Material/Method:This is a retrospective study…
  • 2013 American Transplant Congress

    RIP3 Mediated Necroptosis Regulates Cardiac Allograft Inflammation and Survival

    A. Pavlosky, X. Huang, A. Lau, Z. Yin, A. Haig, A. Jevnikar, Z. Zhang

    Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, ON, Canada; Medicine, Western University, London, ON, Canada; Pathology, Western University, London, ON, Canada

    Despite recent advances in immunosuppression, patients who have undergone allogeneic cardiac transplantation still suffer from poorly understood chronic graft loss. Previous studies have shown that…
  • 2013 American Transplant Congress

    Everolimus Facilitated Reduction of Tacrolimus in De Novo Liver Transplant Recipients: 12-24 Month Data from North America

    W. Chapman, R. Brown Jr, D. Sudan, K. Chavin, B. Koneru, M. Huang, G. Junge, J. Hexham, G. Dong, A. Wiland, J. Fung

    Washington Univ School of Medicine, St Louis, MO; Columbia Univ Medical Center, New York, NY; Duke Univ Medical Center, Durham, NC; Medical Univ of SC, Charleston, SC; Univ of Medicine and Denstistry-NJ Medical School, Newark, NJ; Henry Ford Hosp, Detroit, MI; Novartis AG, Basel, Switzerland; Novartis Pharmaceuticals Corporation, East Hanover, NJ; Cleveland Clinic, Cleveland, OH

    Purpose: In Study H2304, everolimus (EVR) facilitated early tacrolimus (TAC) minimization with comparable efficacy and better renal function vs standard TAC at 12 months (M)…
  • 2013 American Transplant Congress

    Anti-Inflammatory Effects of Prednisolone Treatment Did Not Improve Organ Quality in Brain Dead Rats

    R. Rebolledo, B. Liu, A. Van Erp, P. Ottens, S. Veldhuis, H. Leuvenink

    Departament of Surgery, University Medical Center Groningen (UMCG), Groningen, Netherlands; Facultad de Medicina, Universidad de Chile, Santiago, Chile

    IntroductionOur previous results showed a protective effect in kidney function but not in liver injury with the pre-treatment of brain dead (BD) rat donors with…
  • 2013 American Transplant Congress

    Protocol Biopsies in ABO-Incompatible Versus ABO-Compatible Living Donor Kidney Transplant Recipients

    A. Sanchez-Escuredo, F. Diekmann, I. Revuelta, M. Solé, J. Cid, M. Lozano, M. Blasco, J. Campistol, F. Oppenheimer

    Nephrology and Transplant, H. Clinic, Barcelona, Spain; Pathology, H. Clinic, Barcelona, Spain; Haematology and Haemotherapy, H. Clinic, Barcelona, Spain

    Introduction: Short and medium term ABO-incompatible kidney transplant results are comparable with ABO-compatible kidney transplants (KT). Little is known about the histologic evolution of protocol…
  • 2013 American Transplant Congress

    MnTMPyp, a Selective Superoxide Dismutase Mimetic, Reduces Oxidative Stress in Brain Dead Donors

    D. Hoeksma, L. van Dullemen, P. Ottens, S. Veldhuis, R. Ploeg, H. Leuvenink

    Surgery, University Medical Center Groningen, Groningen, Netherlands; Surgery, University of Oxford, Oxford, United Kingdom

    Renal allografts retrieved from brain dead donors show inferior transplant outcomes compared to living donor grafts. Brain death (BD) leads to immunological activation and hemodynamic…
  • 2013 American Transplant Congress

    Prolonged Extraction Time of Kidneys from Deceased Donors Impacts Function

    A. Osband, N. James, C. Keating, D. Segev

    Kidney/Pancreas Transplant Surgery, Robert Wood Johnson Medical School, New Brunswick, NJ; Surgery, Johns Hopkins University School of Medicine, Baltimore, MD; New Jersey Sharing Network, New Providence, NJ

    Background: Cold and warm ischemia times are known to impact DGF (delayed graft function) rates and long-term allograft survival following deceased donor kidney transplantation. We…
  • 2013 American Transplant Congress

    Impact of Disease Duration on Islet Yield for Clinical Islet Autotransplants for Chronic Panreatitis

    M. Takita, R. Shahbazov, M. Kanak, F. Kunnathodi, M. Lawrence, N. Onaca, M. Levy, B. Naziruddin

    Islet Cell Laboratory, Baylor Research Institute, Dallas/Fort Worth, TX; Institute for Biomedical Studies, Baylor University, Waco, TX; Baylor Annette C. and Harold C. Simmons Transplant Institute, Dallas, TX

    Background: Total pancreatectomy followed by autologous islet transplantation (TP-AIT) is an advanced surgical option for refractory chronic pancreatitis (CP) patients. Islet yield is an important…
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