2013 American Transplant Congress
Melatonin and Trimetazidine Cocktail for Increasing Fatty Liver Graft Preservation: AMPK Involvement in Endoplasmic Reticulum Stress and Autophagy Modulation
Background: Despite the improvement in organ preservation, the prolonged cold storage remains a risk factor for liver graft outcome, especially when steatosis is present. Steatotic…2013 American Transplant Congress
Effect of Belatacept on Follicular Helper T Cell and Humoral Response in Sensitized Rhesus Macaques, The
Surgery, Emory University, Atlanta, GA
[Background] The generation of high affinity antibody and B cell memory requires the interaction of antigen-specific B and T cells in lymphoid follicles and the…2013 American Transplant Congress
Conversion from Tacrolimus (TAC) to Sirolimus (SRL)-Based Immunosuppressive Regimen in Kidney Transplant Recipients: 2 Years Results
Introduction: This multicenter prospective study evaluated renal function of kidney transplant (KT) recipients randomized after the transplant surgery to undergo planned conversion from TAC to…2013 American Transplant Congress
T Cell Senescence and Accelerated Immunologic Aging in Children Awaiting Kidney Transplantation
Introduction: Childhood is a period of dynamic maturation. Pre-clinical studies indicate that the maturation state of pre-transplant (pre-Tx) immune repertoire influences risks of transplantation, such…2013 American Transplant Congress
Critical Analysis of Death within 1 Year after Liver Transplantation, A
Abdominal Transplnatation, University of Arizona, Tucson
Context: In the current era, 15% of liver transplant recipients die within the first year. While this may be viewed as a feat in comparison…2013 American Transplant Congress
Open-Label Study of Planned Transition from Tacrolimus to Sirolimus vs Continued Tacrolimus in Renal Allograft Recipients: Demographics and Interim Safety Results
Purpose: Evaluate planned transition from tacrolimus (TAC) to sirolimus (SRL) vs continued TAC in renal allograft recipients.Methods: This open-label, randomized, multinational phase 4 study screened…2013 American Transplant Congress
Alemtuzumab Induction in HCV Seropositive Kidney Transplant Recipients
Transplant Division, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY
Background: Alemtuzumab (AZ) is a humanized anti-CD52 monoclonal antibody used as an induction agent in organ transplantation. The potency of alemtuzumab, is a concern for…2013 American Transplant Congress
Utility of Bronchoscopy in Post-Transplant Patients Presenting with Symptoms and Signs of Pneumonia
Background: Most studies of the role of bronchoscopy and the epidemiology of pulmonary infections in post-transplant patients focus on stem cell transplant (SCT) recipients. The…2013 American Transplant Congress
Older Living Donor Kidney Transplantation vs. Dialysis on the Waiting List and Standard Criteria Deceased Donor Kidney Transplantation: A Decision Analysis
Medicine, University of Toronto, Toronto, ON, Canada
Background: Living donor (LD) kidney transplantation provides improved outcomes compared with deceased donor (DD) kidney transplantation. Little is known about health gains associated with older…2013 American Transplant Congress
Critical Analysis of Retransplantation within 1 Year after Liver Transplantation, A
Abdominal Transplantation, University of Arizona, Tucson, AZ
Context: Five percent of liver transplant recipients require retransplantation within the first year. In light of the critical donor shortage, a critical analysis of risk…