Abstracts Archive - Page 154 of 1683 - ATC Abstracts

2022 American Transplant Congress
Delivery of Extracellular Matrix Targeted Regulatory T Cells by Novel Nanofiber Coatings for Transplantation Therapies
L. Gallon¹, J. K. Carrow², J. He¹, Y. Sambandam¹, X. Lai¹, J. Mathew¹, L. C. Palmer², J. R. Leventhal¹, Z. Zhang¹, S. I. Stupp²
¹Surgery - Transplant, Northwestern University, Chicago, IL, ²Simpson Querrey Institute, Northwestern University, Chicago, IL
*Purpose: Regulatory CD4+CD25+FOXP3+ T cells (Tregs) have been shown to induce tolerance in transplantation models and can mitigate transplant rejection or injury following ischemic reperfusion…
2022 American Transplant Congress
A Retrospective Evaluation of Organ Donation in the United States: Trends in Donors and Organ Utilization Over 15-Years
J. A. Steggerda¹, I. K. Kim², D. Borja-Cacho¹
¹Transplant Surgery, Northwestern Memorial Hospital, Chicago, IL, ²Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA
*Purpose: The general population of the United States has changed considerably over the past 15 years. This study evaluates longitudinal changes in potential organ donors…
2022 American Transplant Congress
Mass Cytometry Reveals Single-cell Kinetics Of Cytotoxic Lymphocyte Evolution In Cmv-infected Renal Transplant Patients
K. Ishiyama¹, J. Arakawa-Hoyt¹, O. Aguilar¹, T. Sigdel¹, S. Tamaki¹, J. Babdor¹, M. Spitzer¹, E. Reed², M. Sarwal³, L. Lanier¹
¹UCSF, San Francisco, CA, ²Univ of California LA, Los Angeles, CA, ³University of California San Francisco, San Francisco, CA
*Purpose: Cytomegalovirus (CMV) infection is associated with graft rejection in renal transplantation. Memory-like NK cells expressing NKG2C and lacking FcεRIγ are established during CMV infection.*Methods:…
2022 American Transplant Congress
Circulating Galectin-3 Levels Increase in Syngeneic Rat Recipients of Vascularized Composite Allografts Subjected to Prolonged Ischemia
Z. Wang¹, B. Li¹, Y. Wang¹, D. Yoeli¹, N. Nakra¹, N. Limon De La Rosa¹, A. A. Su¹, A. Jani¹, D. W. Mathes¹, K. M. Washington¹, E. Farkash², C. A. Huang¹
¹University of Colorado, Denver | Anschutz Medical Campus, Aurora, CO, ²University of Michigan, Ann Arbor, Ann Arbor, MI
*Purpose: During the process of transplantation, organs and tissue are necessarily subjected to some degree of hypoxic and ischemic injury during procurement, preservation and following…
2022 American Transplant Congress
Benefits of Inactivated Vaccine and Viral Vector Vaccine Immunization on Covid-19 Infection in Kidney Transplant Recipients
N. Sutharattanapong, S. Thotsiri, S. Kantachuvesiri, P. Wiwattanathum
Excellent Center of Organ Transplantation, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
*Purpose: Most developing countries do not have access to high-efficiency mRNA vaccine. In Thailand, the first and most available vaccines were inactivated, and later on,…
2022 American Transplant Congress
A Sustained Injury Response by Regulatory T Cells (Treg) Contributes to Fibrosis to Promote Chronic Rejection After Heart Transplantation
J. Bou Saba¹, L. Fan¹, X. Zhang¹, T. Li¹, L. R. Mathews¹, G. Dwyer², E. Colon², M. J. Calderon³, K. E. Helfrich³, M. A. Ross³, S. C. Watkins³, H. Turnquist¹
¹Surgery, University of Pittsburgh, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, ²Immunology, University of Pittsburgh, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, ³Cell Biology, University of Pittsburgh, Center for Biologic Imaging, Pittsburgh, PA
*Purpose: Chronic rejection (CR) results from the development of immunosuppressant-resistant allograft vasculopathy and fibrosis and remains a leading cause of recipient death one-year post-heart transplant…
2022 American Transplant Congress
Effect of Anti Thymocyte Globulin Induction Therapy in Kidney Transplantation Network Meta-Analysis Using Recent Data
S. Hwang, J. Song, K. Kim, S. Lee
Inha University, Incheon, Korea, Republic of
*Purpose: The use of induction immunosuppressant agents in transplantation is important factors in preserving graft kidney function to prevent rejection. However the question of which…
2022 American Transplant Congress
Single-Cell Multiomics Defines Tolerogenic Extrathymic Aire-Expressing Cells
A. R. Gupta¹, J. Wang², C. Lareau³, I. Sun², J. Bautista¹, J. Gardner¹
¹Department of Surgery, University of California San Francisco, San Francisco, CA, ²Diabetes Center, University of California San Francisco, San Francisco, CA, ³Department of Pathology, Stanford University, Stanford, CA
*Purpose: The Autoimmune Regulator (Aire) gene, essential for central tolerance through its regulation of tissue-specific antigens in medullary thymic epithelial cells, is also expressed in…
2022 American Transplant Congress
Impact of ATG Dose Reduction on Kidney Transplant Outcomes During the Covid-19 Pandemic
P. A. Than¹, F. De Leon¹, K. Jen², N. Goussous¹, R. V. Perez¹, A. X. Wang³
¹Transplant Surgery, UC Davis, Sacramento, CA, ²Pathology, UC Davis, Sacramento, CA, ³Transplant Nephrology, UC Davis, Sacramento, CA
*Purpose: During the COVID-19 pandemic, many transplant centers modified induction immunosuppression regimens. Beginning December 2020, our center reduced anti-thymocyte globulin (ATG) protocol dosing by up…
2022 American Transplant Congress
Robotic-Assisted Reconstruction of the Transplant Ureter: A Minimally Invasive Option for a Rare Complication
A. Popovic¹, M. Hanlon², S. Iskhagi², R. Saidi², S. Blakely³, R. Shahbazov²
¹Urology, Upstate Medical University, Syracuse, NY, ²Surgery, Division of Transplantation, SUNY, Upstate Medical University, Syracuse, NY, ³Urology, SUNY, Upstate Medical University, Syracuse, NY
*Purpose: Ureteric stricture are rare after kidney transplants but nonetheless this complication requires reconstruction in the majority of cases to avoid graft dysfunction and/or failure.…