ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Complication Free Heterotopic Cardiac Xenograft Survival by Anti CD40 Antibody Mediated Co-Stimulation Blockade

    A. Singh, P. Corcoran, B. Lewis, R. Hoyt, M. Thomas, M. Eckhaus, C. Mayhew, T. Clark, K. Reimann, D. Ayares, K. Horvath, M. Mohiuddin

    NHLBI / NIH, Bethesda; ORS/NIH, Bethesda; Revivicor, Inc, Blacksburgh; Beth Israel Deaconess Hospital, Boston

    Introduction: Despite achieving longest reported graft survival by us via anti CD154 mediated co stimulation blockade, many coagulation disorders were witnessed due to direct binding…
  • 2013 American Transplant Congress

    Discriminating among the Sickest Cohorts in Liver Transplantation: An Application of the SOFT Score

    A. Rana, M. Porubsky, T. Jie, S. Habib, H. Rilo, B. Kaplan, A. Gruessner, R. Gruessner

    Abdominal Transplantation, University of Arizona, Tucson, AZ

    Context: Models that discriminate among the sickest cohorts in liver transplantation are important to optimize outcomes. We introduced the Survival Outcomes Following Liver Transplantation (SOFT)…
  • 2013 American Transplant Congress

    Importance of MDR1 Gene Polymorphisms for Calcineurin Inhibitors Dosage and Early Kidney Graft Function, The

    M. Kravljaca, V. Pravica, E. Savic, V. Brkovic, V. Lezaic, R. Naumovic

    Clinic of Nephrology, Clinical Center of Serbia, Belgrade, Serbia; Institute of Microbiology and Immunology, School of Medicine, University of Belgrade, Belgrade, Serbia; School of Medicine, University of Belgrade, Belgrade, Serbia

    Calcineurin inhibitors (CNIs) are a substrate of P-glycoprotein, the product of the multidrug resistance (MDR1) gene and has been known to undergo extensive hepatic metabolism…
  • 2013 American Transplant Congress

    mCMV Infection Increases Migration of Graft-Reactive CD8+ T Cells into the Allograft Impairing Regulatory T Cell Survival

    I. Ferrer, K. Wood

    Nuffield Department of Surgical Sciences, University of Oxford, Headington, United Kingdom

    The advent of immunosuppression has been invaluable in prolonging survival of transplanted organs. However, systemic immunosuppression renders individuals vulnerable to infections that may trigger rejection…
  • 2013 American Transplant Congress

    Impact of Hyperuricemia on Outcomes of Kidney Transplantation: Analysis of the FAVORIT (Folic Acid for Vascular Outcome Reduction in Transplantation) Trial, The

    R. Kalil, S. Campbell, M. Carpenter, M. Weir, T. Pesavento, M. Pfeffer, S. Solomon, W. Haynes, L. Hunsicker

    Medicine, University of Iowa, Iowa City; College of Public Health, University of North Carolina, Chapel Hill; Medicine, University of Maryland, Baltimore; Medicine, Ohio State University, Columbus; Brigham and Women's Hospital, Boston

    Elevated uric acid (UrAc) levels are associated with higher rates of cardiovascular (CV) morbidity and mortality in the general population. Single center studies suggest an…
  • 2013 American Transplant Congress

    Early Look at the OPTN Explant Pathology Form Data, An

    A. Harper, E. Edwards, J. Heimbach, R. Hirose, R. Freeman, K. Olthoff

    Uniited Network for Organ Sharing, Research, Richmond, VA; Surgery, Mayo Clinic, Rochester, MN; Surgery, UCSF Medical Center, San Francisco, CA; Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH; Surgery, The Hosp of the Univ of Pennsylvania, Phildelphia, PA

    Background: Candidates with exceptions for hepatocellular carcinoma (HCC) accounted for 29% of liver transplants during the first 6 months of 2012. OPTN policy requires submission…
  • 2013 American Transplant Congress

    Exogenous Hydrogen Sulphide Mitigates Long-Term Renal Dysfunction Associated with Warm Renal Ischemia-Reperfusion Injury

    J. Zhu, I. Lobb, W. Liu, B. Garcia, Z. Lan, A. Sener

    Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, ON, Canada

    Background:The incidence of renal cell carcinoma (RCC) is concurrently rising with increased prevalence of end-stage renal disease (ESRD) world-wide. Treatment for RCC is limited and…
  • 2013 American Transplant Congress

    Super Regions Can Reduce Geographic Disparities in Liver Transplantation

    A. Rana, M. Porubsky, T. Jie, S. Habib, H. Rilo, B. Kaplan, A. Gruessner, R. Gruessner

    Abdominal Transplantation, University of Arizona, Tucson

    Context: The significant geographic disparities in liver transplantation have been a point of contention in the transplant community. In the attempt to establish greater equity,…
  • 2013 American Transplant Congress

    Promising Outcomes after Long-Term Therapy with Everolimus in Kidney Transplant Patients: Two-Years Results of the CERTIC Registry

    M. Carmellini, S. Federico, P. Messa, G. Gubbiotti, M. Salvadori, D. Colombo, R. Brusa, C. Ponticelli

    AOU Senese - Policlinico Santa Maria alle Scotte, Siena, Italy; AOU Policlinico Federico II - Università degli Studi, Napoli, Italy; Fondazione Ospedale Maggiore Policlinico, Milano, Italy; AO - Ospedale Santa Maria della Misericordia, Perugia, Italy; AOU Careggi - Villa Monna Tessa, Firenze, Italy; Novartis Farma, Origgio (VA), Italy; Humanitas Institute, Milano, Italy

    Everolimus, a mammalian target of rapamycin (mTOR) inhibitor, is licensed for the prevention of acute rejection in heart or kidney transplant recipients. Based on the…
  • 2013 American Transplant Congress

    Evolving Trends in Living Donor Uninephrectomy Techniques and Impact on Post-Transplant Outcomes: A Review of the US National Cohort

    J. Verbesey, M. Grafals, M. Cooper, J. Moore, S. Ghasemian, C. Nilubol, B. Javaid

    MedStar Georgetown Transplant Institute, Washington, DC

    Background: In the US majority of living donor uninephrectomy procedures for kidney transplantation are currently done by laparoscopic techniques. We wanted to assess the variations…
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