2013 American Transplant Congress
Duct-to-Duct Biliary Reconstruction in Liver Transplantation for Primary Sclerosing Cholangitis Is Associated with Less Biliary Complications, Compared with Roux-en-Y Hepatico-Jejunostomy
Background:Although duct-to-duct anastomosis has been shown as a feasible option for biliary reconstruction in patients undergoing orthotopic liver transplantation (OLT) for end-stage primary sclerosing cholangitis…2013 American Transplant Congress
Prioritization Due to Dialysis Access Failure Impacts on Patient Survival after Kidney Transplantation
Renal Transplant Service, Hospital das Clínicas University of São Paulo, São Paulo, Brazil
Dialysis vascular access failure, recipient of a non-renal solid organ transplantation and previous kidney donation are current indications of priority allocation (PA) for kidney transplant…2013 American Transplant Congress
IL-21R+ Marginal Zone Precursor (MZP) B Cells in the Germinal Center Induce IL-10 Dependent Allogeneic Tolerance
National Centre for Cell Science, Pune, MH, India; University of Maryland, Baltimore, MD
Background: B cells have regulatory functions and promote tolerance by inducing deletion or anergy of CD8+ T cells, increasing Foxp3+Treg, inhibiting proliferation of CD4 T…2013 American Transplant Congress
Donor-Derived Semimature Dendritic Cells Transfusion Inducing Tolerance in Acute Rejection of Rat Liver Transplantation
Background and Objective: We recently found that donor semimature dendritic cells (smDCs) could promote skin allograft survival in mice by activating host antigen-specific CD4+CD25+Foxp3+T-regulatory cells…2013 American Transplant Congress
Net Time-Dependent ROC Curves: A New Method for Evaluating the Accuracy of a Marker To Predict Mortality Related to End-Stage Renal Disease in Kidney Transplant Recipients
Identifying prognostic markers of mortality in transplantation is essential for determining patients at high-risk of death and optimizing medical management. Nevertheless, an important part of…2013 American Transplant Congress
IL-1β Polymorphism Increase Susceptibility to Invasive Mold Infection after Solid Organ Transplantation (SOT)
Background Polymorphisms in innate immune genes such as pattern recognition receptors (TLR1, TLR4, Dectin-1), cytokines (TNF-Α, IL-1Β) or other molecules (CARD9, Β-defensin1 [DEFB1]) were previously…2013 American Transplant Congress
Induced Pluripotent Stem Cells from Familial Amyloidotic Polyneuropathy Patients
Backgroud: Familial amyloidotic polyneuropathy (FAP) is an autosomal-dominant hereditary systemic amyloidosis induced by amyloidogenic transthyretin (ATTR). Because most transthyretin (TTR) in serum is synthesized by…2013 American Transplant Congress
Intravital Two-Photon Imaging of Neutrophil Recruitment Reveals an Efficacy of FPR1 Blockade To Attenuate the Hepatic Ischemia-Reperfusion Injury
Transplantation and Pediatric Surgery, Kumamoto University, Kumamoto, Japan
Background: Evidence is accumulating that formyl-peptide receptor (FPR) signaling constitutes an important danger signal that guide neutrophils to sites of inflammation. This study aimed to…2013 American Transplant Congress
Surviving B Cells in Different Lymphoid Organs after Rituximab Administration and Its Association with Clinical Outcomes
Urology, Akita University Graduate School of Medicine, Akita, Japan
BackgroundRituximab (RIT), anti-CD20 antibody, has been applied to kidney transplantation because of its potent B-cell depleting effect. Although CD20+ cells in peripheral blood (PB) and…2013 American Transplant Congress
Multistate Model To Investigate the Relationship between Pre-Graft Level of Angiotensin II Type 1 Receptor (AT1R) Antibodies and Kidney Transplant Recipients Outcome, A
Antibodies reactive with non-HLA target-angiotensin II type 1 receptor (AT1R) have been found during acute rejection with vascular involvement in kidney transplants recipients (KTR). We…