2013 American Transplant Congress
Intrahepatic Cholangiocarcinoma (I-CC) or Mixed Hepatocellular-Cholangiocarcinoma (HCC-CC) in Patients Undergoing Liver Transplantation (LT). A Spanish Case Control Multicenter Study
Aim: to evaluate the outcome of patients with HCC-CC or I-CC at explant pathology after LT for suspected HCC.Methods:A case-control study 1:2. Study group(n=42) formed…2013 American Transplant Congress
Pre-Transplant Immediately Early-1-Specific T-Cell Responses Provides Protection for CMV Infection after Kidney Transplantation
Human cytomegalovirus (CMV) infection is still a major complication after kidney transplantation. Although it is well known that cytotoxic CMV-specific CD8+ T cells play a…2013 American Transplant Congress
Soluble BAFF Levels Correlate with De Novo DSA Development and Progression to Chronic Active Antibody-Mediated Rejection in Pediatric Recipients of First Kidney Transplants
De novo donor-specific antibody (dnDSA) development is associated with late/chronic active antibody-mediated rejection (CAMR) and graft failure in low-risk kidney recipients. It has been recently…2013 American Transplant Congress
Disappearance of Immunoglobulin Producing Plasmablasts in Kidney Transplant Patients Is Associated with a Diminished Cytokine Producing Capacity by Peripheral Follicular T-Lymphocytes
Internal Medicin & Transplant Immunology, Erasmus MC, Rotterdam, South-Holland, Netherlands
BACKGROUND Follicular T-helper cells (Thf-cells) play a pivotal role in the differentiation of B-cells into Ig secreting cells, i.e. plasmablasts. CD4+CXCR5+ T-cells are their peripheral…2013 American Transplant Congress
E-Cad Promotes Liver Tissue Formation in Hepatic Differentiation of Mouse Embryonic Stem Cells through Regulating the Differentiation Progress
Objective Until now, the hepatic differentiation of embryonic stem cells (ESCs) usually results in single cell lineage and could not form liver tissues. In this…2013 American Transplant Congress
Late Extra-Hepatic Biliary Strictures after Liver Transplantation: First Evidence of Association with Pre-Existing Donor Specific Antibodies
Late biliary strictures following liver transplantation are a major source of graft loss, and usually attributed to vascular problems. In many cases, however, vascular pathologies…2013 American Transplant Congress
CCR2 Dependent Migration Is Absolutely Required for Myeloid Suppressor Cells To Protect Cell Transplants
Whole organ transplantation gets great success, while the outcomes of cell transplants remain poor, suggesting a critical role of non-parenchymal cells in immune regulation. Through…2013 American Transplant Congress
Kidney Transplantation: Pre and Post-Transplant Immunological Evaluation and Outcome of Recipients in Low, Medium, and High Risk of Rejection
Specific antibodies (AB) against donor (DSA) have a fundamental role in the mechanism of kidney (K) transplant rejection and represent one of the main barriers…2013 American Transplant Congress
Prolonged Cardiac Allograft Survival Due to Treg Expansion in Recipient BAFF-Tg Mice
Background: B cell activation factor of the TNF family (BAFF) is considered to function as a proinflammatory cytokine. BAFF is crucial for B cell development…2013 American Transplant Congress
Induction of Donor Specific Hyporesponsiveness in Kidney Transplantation Using Adoptive Transfer of Ex Vivo Induced Tolerogenic Cells
[Background] Anergic T cells generated ex vivo under conditions of co-stimulatory blockade are reported to have tolerogenic effects. According this finding, we have conducted the…