2013 American Transplant Congress
IL-33 Receptor Expression by Cardiac and Aortic Allografts Limits Immune Infiltration and Development of Vasculopathy
Overview: Studies have found administration of IL-33 triples the survival of MHC-mismatched murine heart transplants (HTx) in the absence of any immunosupression. These data are…2013 American Transplant Congress
Transplant Certification and Quality Assessment: The Effect of Center Data Input Quality
Each transplant program in the United States is required to submit self-reported data to OPTN/UNOS to calculate a centers performance. Currently, under the Conditions of…2013 American Transplant Congress
Neutralization of IL-23 Is Protective Against Hepatic Cold Ischemia/Reperfusion (I/R) Injury
Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA
Purpose: Interleukin-23 (IL-23) can activate inflammatory pathways such as CD4+ cell differentiation into IL-17 secreting Th17 cell type and increased production of IFNg leading to…2013 American Transplant Congress
Risk Factors, Rejection and Infections Associated with Neutropenia in Solid Organ Transplantation: A Retrospective Study
Introduction: Neutropenia is relatively frequent after solid organ transplantation (SOT). Its risk factors have been scarcely studied and its consequences remain to be defined in…2013 American Transplant Congress
Common Rejection Module (CRM) across Multiple Transplant Organs Identifies Novel Therapeutics for Treatment of Acute Rejection in Solid Organ Transplantation, A
We performed meta-analyses of eight datasets comprising whole genome microarray expression profiles on 236 graft biopsy samples from four types of transplanted organs (kidney, lung,…2013 American Transplant Congress
For Cause Renal Biopsies Are Heterogeneous Irrespective of Clinical Presentation
St.James's University Hospital, Leeds, United Kingdom
Deteriorating renal function either evidenced by a rise in serum creatinine or proteinuria remains the most important indication for a late transplant biopsy. Over the…2013 American Transplant Congress
Age Disparities in Discussions about Kidney Transplantation among Dialysis Patients
BACKGROUND: Older patients show improved survival and quality of life following kidney transplantation (KT) compared to those who remain on dialysis, yet referral for KT…2013 American Transplant Congress
Human Insulinoma Expression of E2F Reveals a Role in Beta-Cell Proliferation and Quiescence
Surgery - Transplant, University of Illinois at Chicago, Chicago, IL
Reversal of diabetes in patients through islet cell transplant is quickly becoming a reality. However, cadaver organ donations, the current source of islets for transplant,…2013 American Transplant Congress
Six Minute Walk Distance, Sarcopenia and Cardiopulmonary Assessment in Candidates for Liver Transplantation
Evaluation for liver transplantation (LT) focuses on organ-specific testing intended to determine a candidates fitness for transplantation. However, simple tests of global physical function may…2013 American Transplant Congress
Efficient Identification of All Grades of Antibody Mediated Rejection (AMR) and Mixed Rejection with a Unique Immunohistochemical Panel in Heart Transplant Patients
Antibody Mediated Rejection (AMR) following heart transplantation is increasingly recognized as a substantial complication that increases risk for graft failure, vasculopathy, and decreased recipient survival.…