2013 American Transplant Congress
Mice, Men and Math: Finding Novel Drugs for Organ Transplantation
To ensure long term allograft function and reduce non-tolerable side effects, novel immunosuppressive drugs are needed in Transplantation. In a novel bioinformatics driven drug discovery…2013 American Transplant Congress
High Creatinine and Advanced Chronic Rejection (CR) Predicts Graft Loss in Non Adherent Kidney Transplant Recipients
University of Minnesota, Minneapolis, MN
The risk factors for graft loss in kidney transplant recipients (KTR) with non-adherence (NA) to immunosupression who present with rejection are not known.We analyzed 208…2013 American Transplant Congress
Acute Rejection in Older Kidney Transplant Recipients
Johns Hopkins University School of Medicine, Baltimore, MD
BACKGROUND: Age limits for transplantation have expanded significantly in the last 20 years, with a 5-fold increase in the number of older adults receiving kidney…2013 American Transplant Congress
Th17 Memory Cells Are More Dependent on Coinhibition by CTLA-4 Than Th1 Memory Cells and Are Associated with Rejection in Patients Treated with Belatacept
Emory Transplant Center, Atlanta, GA
T cell memory is comprised of an assortment of phenotypic lineages suited for microbial immunity that may cross-react with allogeneic antigens to drive pathological immune…2013 American Transplant Congress
Extended Criteria Donor (ECD) Renal Allograft Use in Older Recipients in a Short Wait Time Center: Is There an Advantage?
Surgery, Univeristy of Florida, Gainesville, FL; Medicine, Univeristy of Florida, Gainesville, FL
Merion et al. (JAMA, 2005) concluded that ECD renal grafts benefit a recipient if they are older than 40 with hypertension or diabetes, and have…2013 American Transplant Congress
TOL101 Signaling Pathways, a Novel CD3 Independent T Cell Inactivation & Treg Induction Cascade
In a Phase 2 renal transplant study, the anti-ΑΒ TCR antibody TOL101 inhibited T cell function in transplant patients at a range of doses. When…2013 American Transplant Congress
Living Donor Kidney Transplantation in the Pediatric Population: Risk Factors for Adverse Outcomes
Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Purpose: To review the pediatric recipients of laparoscopic donor nephrectomy (LDN) at our institution and examine predictors of adverse outcomes, particularly in patients ≤5 years…2013 American Transplant Congress
Living Donor Liver Transplantation for High MELD Score Patients
Background: Liver transplantation is the only effective treatment for the very sick liver failure patients. For the success of liver transplantation, it is better to…2013 American Transplant Congress
Lower Serum Magnesium 1-Year Posttranplantation Is Associated with Decreased Graft Survival in Renal Transplant Recipients
Hypomagnesaemia is a known side effect of immunosuppressive regimen, especially calcineurin inhibitors, and has been associated with new onset diabetes after transplantation (NODAT), decreased graft…2013 American Transplant Congress
Minimization of Immunosuppression for ABO-Incompatible Kidney Transplantation Based on the Strength of Pretreatment Anti A/B Antibody Titer
Acute antibody mediated rejection (AMR) used to be a major problem in ABO-incompatible KidneyTransplantation (ABOi-KTx), and currently rituximab has been accepted to reduce the prevalence…
American Transplant Congress abstracts