ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Specificity and Avidity of Donor MHC-Specific B Cells in Naive, Rejecting and Tolerant Mice

    I. Sayin1, S. Khiew2, D. Yin1, P. Sage3, C. B. Cavazzoni3, R. King4, A. Chong1

    1Department of Surgery, University of Chicago, Chicago, IL, 2Merck, Boston, MA, 3Brigham and Women's Hospital, Boston, MA, 4Department of Microbiology, University of Alabama, Birmingham, AL

    *Purpose: Antibody-mediated rejection is recognized as an important mediator of graft loss in the clinic, and the induction of donor-specific B cell tolerance may contribute…
  • 2022 American Transplant Congress

    Assessment of Insulin Utilization for Early Post-Transplant Glycemic Control in Liver Transplant

    L. F. Borges, K. Gutierrez, T. A. Sparkman, J. Banbury

    UAB Hospital, Birmingham, AL

    *Purpose: Transient hyperglycemia after liver transplant (LT) is common due to the use of high-dose steroids at the time of transplant, but some patients may…
  • 2022 American Transplant Congress

    Optimal Development and Effector Function of Antibody-Suppressor CXCR5+CD8+ T Cells Requires Host IFN-γ and CD4+ T Cells

    J. Zimmerer, S. Chaudhari, M. Hart, J. Han, K. Koneru, G. Bumgardner

    OSUWMC, Columbus, OH

    *Purpose: We reported the discovery of a novel subset of CXCR5+IFNγ+CD8+ T cells that suppresses antibody production (CD8+ TAb-supp cells). Alloprimed CD8+ TAb-supp cells significantly…
  • 2022 American Transplant Congress

    Three‐Month Pancreas Graft Function Significantly Influences Survival Following Simultaneous Pancreas‐Kidney Transplantation in Type 1 Diabetes Patients

    M. Ji1, S. Chang1, M. Wang1, K. Lentine2, M. Merzkani1, H. Murad1, M. M. Ibrahim1, M. Zayed1, J. Wellen1, S. Sutcliffe1, T. Alhamad1

    1Washington University in St. Louis, Saint Louis, MO, 2Saint Louis University, Saint Louis, MO

    *Purpose: Simultaneous pancreas-kidney transplantation (SPK) is the only persistently successful treatment option for patients with diabetes mellitus and end-stage renal disease. However, SPK carries a…
  • 2022 American Transplant Congress

    Measurement of Physical Activity and Frailty in the Early Post-Operative Period After Kidney Transplant-Single-Center Prospective Pilot Study Using Fitbit Watch

    T. Shamaa, L. Allenspach, O. Shamaa, S. Shimada, C. Crombez, O. Hage-Hassan, T. Kitajima, S. Yeddula, I. Bajjoka, L. Malinzak, J. Denny, D. Kim, M. Abouljoud, S. Nagai

    Henry Ford Transplant Institute, Detroit, MI

    *Purpose: Physical activity monitors (PAMs) allow patients to track multiple health parameters. PAM’s may be helpful to assess a patient’s physical recovery after a Kidney…
  • 2022 American Transplant Congress

    Final Flow and Resistance During Cold Pulsatile Perfusion Preservation Do Have Value in Prediction of Deceased Donor Graft Survival After Adjusting for KDPI

    D. S. Keith, E. Lessmann

    Kidney Transplant, Sacred Heart Hospital, Pensacola, FL

    *Purpose: To determine whether cold pulsatile perfusion preservation (CPPP) parameters of flow and resistance provide additional data regarding deceased donor kidney graft survival after adjusting…
  • 2022 American Transplant Congress

    Impact of COVID-19 on Increased Mortality in Liver Transplant Recipients in United States

    K. Okumura, A. Dhand, R. Misawa, H. Sogawa, R. Bodin, D. C. Wolf, S. Nishida

    Westchester Medical Center / New York Medical College, Valhalla, NY

    *Purpose: COVID-19 pandemic has had a significant impact on access to routine healthcare in both hospitalized and out-patient settings. This impact was also noted in…
  • 2022 American Transplant Congress

    CCR2 Antagonism Blocks Microbiota Pro-Inflammatory Effects on Lymph Node Architecture

    S. J. Gavzy1, R. Lakhan2, J. Iyyathurai2, V. Saxena2, Z. L. Lee2, B. Ma2, E. Mongodin2, J. S. Bromberg2

    1University of Maryland School of Medicine, Baltimore, MD, 2University of Maryland, Baltimore, MD

    *Purpose: Fecal microbiota transfer (FMT) of Desulfovibrio desulfuricans (Desulfo) triggers a pro-inflammatory immune state, causing decreased laminin α4:α5 ratios in the lymph node (LN), increased…
  • 2022 American Transplant Congress

    Early Il-33 Action on Myeloid Cells is Critical In Resistance to Systemic Candida Albicans Infection

    H. Cho1, S. Park1, B. Kwon2, H. Park1, Y. Kim3, J. Lee4, J. Park4, K. Park4, K. Yoo4

    1Department of Surgery, University of Ulsan College of Medicine, Ulsan, Korea, Republic of, 2School of Biological Sciences, University of Ulsan, Ulsan, Korea, Republic of, 3Biomedical research center, Ulsan University Hospital, Ulsan, Korea, Republic of, 4Department of Internal Medicine, University of Ulsan College of Medicine, Ulsan, Korea, Republic of

    *Purpose: Invasive candidiasis could be a cause of morbidity and mortality in immunocompromised patients with organ or bone marrow transplantation. In this study, we systematically…
  • 2022 American Transplant Congress

    Demographic Characteristics of VCA Candidates and Recipients in the U.S.

    J. Wainright1, L. Cartwright1, A. Henderson1, W. Cherikh1, S. Booker1, D. Klassen2

    1Research, UNOS, Richmond, VA, 2Office of the Chief Medical Officer, UNOS, Richmond, VA

    *Purpose: As with other fields of transplantation, it is important to understand the populations VCA transplantation is serving.*Methods: This study used OPTN VCA waiting list…
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