2013 American Transplant Congress
Human Adipose Tissue Derived Mesenchymal Stem Cells Aggravate Chronic Cyclosporin Nephrotoxicity by the Induction of Oxidative Stress
Internal Medicine, Seoul St. Mary's Hospital, Seoul, Korea
Cyclosporine (CsA) induced nephrotoxicity is an important complications to limit the long term allograft outcome in kidney transplantation. The aim of this study was to…2013 American Transplant Congress
Addition of Anti-CMV Ig to Routine CMV Prophylaxis in EBV High Risk Kidney Transplant Recipients Is Associated with Reduced PTLD Incidence
Transplant, University of Cincinnati; Transplant, The Christ Hospital
Epstein-Barr virus (EBV) seronegative patients (pts) who receive a kidney from an EBV seropositive donor carry the highest risk for EBV-related PTLD. We report our…2013 American Transplant Congress
Genetic Polymorphism rs10912564 in TNFSF4 of the TNF Superfamily Is Associated with HCT Outcomes
TNFSF4 is a costimulatory molecule that is important for T cell activation. In this study, we used multivariate Cox regression models to determine whether a…2013 American Transplant Congress
Vascular Endothelial Growth Factor (VEGF) Receptor Mediated Responses in T Cell Subpopulations
Transplant Research Program, Department of Medicine, Boston Children's Hospital, Boston, MA
Recent studies have indicated that the VEGF receptor NRP-1 is expressed on T regulatory cells, and that VEGFR1 and VEGFR2 are expressed on human T…2013 American Transplant Congress
Calculated Panel Reactive Antibody (CPRA) after 2.5 Years: More Extremely Sensitized Kidney Waitlist Registrants but Fewer Organ Refusals for a Positive Crossmatch
UCSF, San Francisco, CA; UNOS, Richmond, VA; Stanford, Palo Alto, CA; Cedars-Sinai, Los Angeles, CA
On 10/1/09, the Organ Procurement and Transplantation Network (OPTN) replaced PRA (listed by transplant centers) with CPRA which is calculated using the unacceptable antigens (UA)…2013 American Transplant Congress
Racial and Ethnic Differences in Determinants of Live Donor Kidney Transplantation in the United States
Johns Hopkins University, Baltimore; University of Washington, Seattle
Purpose: Our objective was to examine racial/ethnic differences in determinants of live-donor kidney transplantation (LDKT) across all major US racial/ethnic groups.Methods: We performed a retrospective…2013 American Transplant Congress
APOL1 and MHY9 Gene Variants and Allograft Outcomes in Kidney Transplantation
Background: Single nucleotide polymorphisms (SNPs) in APOL1 and nearby MHY9 gene have been consistently associated with increased risk of ESKD in African Americans (AA) in…2013 American Transplant Congress
Outcomes of Influenza Infection in Adult Hematopoietic Stem Cell Transplant and Lung Transplant Recipients Compared to Non Transplant Patients
Infectious Disease, Cleveland Clinic, Cleveland, OH
Background:After the Influenza A H1N1 pandemic infection of 2009 there was increased concern regarding worse clinical presentations in transplant recipients. We compared outcomes of influenza…2013 American Transplant Congress
Impact of Induction Agent on Repeat Kidney Transplant Outcomes in Patients on Maintenance Immunosuppression
University of MD Medical Ctr, Baltimore
Background: 12% of kidney transplant recipients each year have undergone previous transplantation. The optimal induction therapy in the subgroup of patients who are on maintenance…2013 American Transplant Congress
Locally-Delivered CD4+CD25highFoxp3+ Regulatory T Cells Combined with Systemic KRP203 Therapy Induces Tolerance to Islet Allografts
Background: KRP203, a structural FTY720 analog, has 5-fold greater selectivity for binding to sphingosine-1-phosphate receptor 1 (S1PR1) versus S1PR3 and 100-fold greater selectivity versus S1PR2…