ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Development of a Post-Graduate Year 2 Solid Organ Transplant Pharmacy Residency Program at an Academic Medical Center

    A. Guyton, D. Clark, M. Todd, J. Peterson, A. James.

    Department of Pharmacy, University of Alabama at Birmingham Hospital, Birmingham, AL.

    The University of Alabama at Birmingham (UAB) Hospital performs a high volume of solid organ transplants each year, allowing for residents and students from many…
  • 2015 American Transplant Congress

    Kidney Transplantation After Hematopoietic Cell Transplantation in Plasma Cell Dyscrasias

    V. Domínguez-Pimentel,1 F. Fortich-Barrios,1 O. Siverio-Morales,1 E. Martín-Izquierdo,1 A. Jarque-López,1 N. Del Castillo-Rodríguez,1 J. García,1 P. Ríos,2 M. Macía.1

    1Division of Nephrology, Hospital Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Spain; 2Division of Hematology, Hospital Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Spain.

    INTRODUCTION:The plasma cell dyscrasias (PCD) include a number of entities such as multiple myeloma (MM), primary amyloidosis (AL) and Monoclonal immunoglobulin deposition disease (MIDD). Hematopoietic…
  • 2015 American Transplant Congress

    Preferences for Policy Options for Deceased Organ Donation for Transplantation: A Discrete Choice Experiment

    K. Howard,1 S. Jan,2 J. Rose,3 G. Wong,1,4 J. Craig,1,4 M. Irving,1 A. Tong,1,4 S. Chadban,1,5 R. Allen,5 A. Cass.6

    1The University of Sydney, Sydney, Australia; 2The George Institute for Global Health, Sydney, Australia; 3Institute for Choice, University of South Australia, North Sydney, Australia; 4Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, Australia; 5Department of Renal Medicine, Royal Prince Alfred Hospital, Camperdown, Australia; 6Menzies School of Health Research, Darwin, Australia.

    Background: Despite broad public support for organ donation, there is a chronic shortage of deceased donor organs. We sought to identify features of an organ…
  • 2015 American Transplant Congress

    Is There a Protective Value for Low Level Donor Specific Antibodies to Prevent Cardiac Allograft Vasculopathy After Heart Transplant?

    M. Kittleson, J. Patel, F. Liou, S. Siddiqui, J. Yabuno, D. Chang, D. Ramzy, L. Czer, F. Esmailian, N. Reinsmoen, J. Kobashigawa.

    Cedars-Sinai Heart Institute, Los Angeles, CA.

    Purpose: Donor specific antibodies (DSA) following heart transplant has been reported to be associated with increased development of cardiac allograft vasculopathy (CAV) and risk of…
  • 2015 American Transplant Congress

    Correlation of Longitudinal Gene-Expression Profiling Score to Cytomegalovirus Infection: Results from the Outcomes AlloMap® Registry

    M. Kanwar,1 J. Yee,2 G. Ewald,3 S. Murali,1 J. Teuteberg.4

    1Allegheny Singer Research Institute, Pittsburgh, PA; 2CareDx, Inc., Brisbane, CA; 3Washington University, St. Louis, MO; 4University of Pittsburgh Medical Center, Pittsburgh, PA.

    Purpose: Cytomegalovirus (CMV) infection has been implicated in the pathogenesis of allograft rejection, which is reflected by high gene-expression profiling (GEP) scores. In the IMAGE…
  • 2015 American Transplant Congress

    Clinical Use of Gene-Expression Profiling to Monitor for Rejection After Cardiac Transplantation – Which Patients and When?

    J. Teuteberg,1 M. Shullo,1 T. Wolf,2 P. Prasad,2 G. Ewald.3

    1University of Pittsburgh Medical Center, Pittsburgh, PA; 2CareDx, Inc., Brisbane, CA; 3Washington University, St. Louis, MO.

    Background: Gene-expression profiling (GEP), in place of endomyocardial biopsy, is increasing. GEP testing is intended for low-risk asymptomatic patients (pts); thus, the profile of pts…
  • 2015 American Transplant Congress

    T-Cell Immune Function Vs. Gene Expression Profiling for Heart Transplant Rejection

    M. Luu, M. Kittleson, J. Patel, F. Liou, S. Siddiqui, L. Piponniau, A. Hage, D. Chang, L. Czer, A. Trento, J. Kobashigawa.

    Cedars-Sinai Heart Institute, Los Angeles, CA.

    Purpose: Non-invasive immune monitoring of heart transplant (HTx) patients (pts) is increasing in use. The AlloMap® blood test has proven helpful in surveillance of cardiac…
  • 2015 American Transplant Congress

    Late Rejection in Pediatric Heart Transplantation: The Importance of Medical Adherence

    A. Letica, W. Zuckerman, L. Addonizio, J. McAllister, T. Lee, M. Richmond.

    Division of Pediatric Cardiology, Columbia University, New York, NY.

    While the incidence of early rejection (<1 yr post-transplant) after pediatric heart transplant (HT) has decreased, late rejection (> 1 yr post-transplant) remains a constant…
  • 2015 American Transplant Congress

    Long-Term Results After Heart Transplantation – A Randomized Trial Comparing Tacrolimus Versus Cyclosporine A in Combination With Mycophenolate Mofetil After a Mean Duration of 15 Years

    S. Guethoff,1 C. Grinninger,1 B. Reichart,2 P. Ueberfuhr,1 C. Hagl,1 B. Meiser.2

    1Department of Cardiac Surgery, Ludwig-Maximilians University, Munich, Germany; 2Transplantation Center, Ludwig-Maximilians University, Munich, Germany.

    Purpose. Development of cardiac allograft vasculopathy (CAV), renal dysfunction and malignancies are the main risks due to long-term immunosuppressive therapy after heart transplantation (HTx). We…
  • 2015 American Transplant Congress

    The Correlation Between Donor Specific Antibodies and Heart Transplant Rejection

    R. Bedard,1 P. Jindra,2 M. Manson,1 M. Moaddab,1 H. Mallidi,3 W. Etheridge,1 A. Civitello,3 R. Kerman.2

    1CHI St. Luke's Health - Baylor St. Luke's Medical Center, Houston, TX; 2Immune Evaluation Laboratory, Baylor College of Medicine, Houston, TX; 3Texas Heart Institute, Baylor College of Medicine, Houston, TX.

    The presence of donor specific HLA antibodies (DSA) has been shown to be detrimental to heart transplant (HTx) survival. Virtual crossmatching (VXM) offers a rapid…
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