Abstracts Archive - Page 148 of 1683 - ATC Abstracts

2022 American Transplant Congress
The Association of Pre-Transplant Dialysis Time and the Survival Benefit of Deceased Donor Kidney Transplantation
W. F. Parker¹, Y. Becker², R. Gibbons¹
¹University of Chicago, Chicago, IL, ²University of Chicago, Hinsdale, IL
*Purpose: The US Kidney Allocation System (KAS) allows for deceased donor kidney transplant (DDKT) candidates not yet on dialysis to accrue waiting time points by…
2022 American Transplant Congress
Top Molecules Associated with CLAD in Lung Transplants Are Shared Between Mucosal Biopsies, Transbronchial Biopsies, and Kidney Transplant Biopsies at Risk of Progression
M. Mackova¹, K. Halloran², P. F. Halloran¹, .. and the INTERLUNG Study Group³
¹Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ²University of Alberta, Edmonton, AB, Canada, ³., ., AB, Canada
*Purpose: Chronic lung allograft dysfunction (CLAD) is a physiologic state with grave consequences for progression to failure but cannot be diagnosed by biopsy histology. We…
2022 American Transplant Congress
Local Mesenchymal Stem Cell Therapy for the Ex Vivo Preservation of a Porcine Vascularized Composite Allograft with 24-hour Normothermic Machine Perfusion
A. Bernal¹, J. Hinshaw¹, J. Pena¹, C. Hinshaw¹, D. Wood¹, K. Zimmern², N. McMahon², J. Ling², W. Zhang¹, E. Weitzel¹
¹US Army Institute of Surgical Research/59th MDW, San Antonio, TX, ²Southwest Research Institute, San Antonio, TX
*Purpose: Given therapeutic limitations in limb salvage, we sought to demonstrate the efficacy of combining local mesenchymal stem cells (MSCs) infusion with fresh whole blood…
2022 American Transplant Congress
Regional Variation in Early Effects of Acuity Circle-Based Liver Allocation
T. Ivanics¹, S. Nagai², T. Kitajima², S. Shimada², T. Shamaa², K. Collins², M. Rizzari², A. Yoshida², D. Moonka², M. Abouljoud²
¹University of Toronto - University Health Network, Toronto, ON, Canada, ²Henry Ford Hospital, Detroit, MI
*Purpose: Liver allocation in the United States was updated on February 4th, 2020, byintroducing the acuity circle (AC)-based model. This study evaluated the early effects…
2022 American Transplant Congress
Development of a Radiomics-Based Model to Predict Graft Fibrosis in Liver Transplant Recipients: A Pilot Study
F. Qazi Arisar¹, E. Salinas-Miranda², H. Ale Ali², K. Lajkosz³, C. Chen¹, A. Azhie¹, G. M. Healy², D. Deniffel², M. A. Haider², M. Bhat¹
¹Ajmera Transplant Program, University Health Network, Toronto, ON, Canada, ²Lunenfeld Tanenbaum Research Institute, Toronto, ON, Canada, ³Department of Biostatistics, University Health Network, Toronto, ON, Canada
*Purpose: Recurrent fibrosis complicates 40% of Liver transplants (LT), compromising long-term survival. We evaluated the ability of a model combining radiomic features on CT scans…
2022 American Transplant Congress
Angiotensin II-Regulated Proteins Production by Pulmonary Macrophages in Chronic Lung Allograft Dysfunction
S. Farkona¹, A. Duong², G. Berra², S. Moshkelgosha², S. Clotet-Freixas¹, S. Juvet², T. Martinu², A. Konvalinka¹
¹Toronto General Hospital Research Institute and Multi-Organ Transplant, University Health Network, Toronto, ON, Canada, ²Toronto Lung Transplant Program, University Health Network, Toronto, ON, Canada
*Purpose: Chronic lung allograft dysfunction (CLAD), characterized by fibrosis, is the most important cause of mortality after lung transplantation. CLAD mechanisms remain poorly understood and…
2022 American Transplant Congress
Gm2a: A Novel Regulatory Pathway Controlling CD8⁺ T Cell Alloimmunity
K. M. Baecher¹, J. Bazzano¹, K. Tong¹, M. Fribourg², P. Cravedi², P. S. Heeger², M. L. Ford¹
¹Department of Surgery, Emory University, Atlanta, GA, ²Mount Sinai School of Medicine, New York, NY
*Purpose: Transplant recipients experience lifelong immunosuppression, yet studies have shown that a subset of patients may be able to retain stable graft function even with…
2022 American Transplant Congress
Noninvasive Biomarkers for Allograft Monitoring After Intestinal Transplantation: Promising Early Results from a Novel Peptide, REG3α
C. P. Smullin¹, R. S. Venick², E. A. Marcus², B. V. Naini³, D. G. Farmer⁴
¹David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, ²Pediatrics, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, ³Pathology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, ⁴Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA
*Purpose: There is an urgent need for the discovery and application of noninvasive biomarkers to detect allograft rejection after intestinal transplantation (ITx). Calprotectin and citrulline…
2022 American Transplant Congress
Nocardia Infection and Associated Outcomes in Patients with Solid Organ Transplant
R. Munshi¹, J. Pellegrini Jr.¹, M. Lannom¹, N. Nehru², W. Olsthoorn², F. Anjum³
¹Internal Medicine, Nassau University Medical Center, West Hempstead, NY, ²American University of the Caribbean, Cupecoy, Saint Martin, ³Pulmonary and Critical Care, University of Pennsylvania, Philadelphia, PA
*Purpose: Solid organ transplant (SOT) recipients face various challenges including increased risk of infections. Nocardia is a known pathogen for infecting immunosuppressed individuals, however, there…
2022 American Transplant Congress
Safety and Immunogenicity of Live Viral Vaccination After Pediatric Liver and Kidney Transplantation
A. Feldman¹, B. Beaty¹, N. Ebel², J. Ferrolino³, V. Gopalareddy⁴, J. Hollenbeck⁵, C. Jaramillo⁶, N. Kerkar⁷, S. Lerret⁸, G. Maron³, A. Mavis⁹, N. Ovchinsky¹⁰, M. Sell¹¹, T. Sharma¹², J. Stoll¹³, L. Danziger-Isakov¹⁴
¹UCD, Aurora, CO, ²Stanford, Palo Alto, CA, ³St. Jude, Memphis, TN, ⁴LCH, Charlotte, NC, ⁵Michigan Medicine, Ann Arbor, MI, ⁶PCH, Salt Lake City, UT, ⁷URMC, Rochester, NY, ⁸MCW, Milwaukee, WI, ⁹Duke, Durham, NC, ¹⁰Montefiore, NYC, NY, ¹¹MUSC, Charleston, SC, ¹²BCH, Boston, MA, ¹³WUSM, St Louis, MO, ¹⁴CCHMC, Cincinnati, OH
*Purpose: New recommendations suggest that measles-mumps-rubella vaccine (MMR-vx) and varicella vaccine (VZV-vx) may be administered to certain non-immune transplant recipients. The purpose of this study…