2015 American Transplant Congress
Molecular and Functional Immune Assays as Non-Invasive Diagnostic Tools to Assess the Risk of Acute Subclinical Rejection After Kidney Transplantation
Subclinical allograft rejection (sc-AR) is still a main cause of allograft loss that can only be assessed through invasive surveillance biopsies. We sought to investigate…2015 American Transplant Congress
Precision Diagnosis in Kidney Transplantation
Dept of Medicine, Univ of Illinois Chicago, Chicago, IL.
ObjectiveA major objective in clinical practice, including transplantation, is to develop more focused and “personalized” approaches for both diagnosis and treatment. There have been several…2015 American Transplant Congress
Increased Vascular Stiffness in Pediatric Renal Transplant Recipients Despite Normal Kidney Function, Blood Pressure, and Body Mass Index
1Southern Illinois University, Springfield, IL; 2Washington University, St. Louis, MO.
Background: Chronic kidney disease (CKD) imparts enormous cardiovascular (CV) risk that is only partially improved by renal transplantation. We sought to understand the determinants of…2015 American Transplant Congress
Assessment of Viral-Specific Memory T Cell Responses and Infection Rates in HLA-Sensitized (HS) Kidney Transplant Patients (Tx Pts) Treated With Everolimus & Low-Dose Tacrolimus (Eve/Tac)
Transplant Immunology & Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles.
Background: mTOR inhibitors stimulate viral-specific memory CD8+ T cell differentiation and increase viral clearance in infected Tx pts. HS pts desensitized (DES) with IVIG +…2015 American Transplant Congress
Evaluation of Natural Killer Cell Activation by NK Cell-Specific Interferon-Gamma-Releasing Assay
Introduction: Although NK cell activity (NKA) has a variety of measuring markers including chromiun release assay and flowcytometry-based cytolysis, limitations such as radioactivity and lack…2015 American Transplant Congress
Associations Between Deceased-Donor Urine Biomarkers of Kidney Injury and 6-Month Kidney Transplant Function
TRIBE-AKI Consortium, New Haven, CT.
Assessment of organ quality is integral to allocation, yet existing tools have a limited ability to predict important transplant outcomes. We evaluated whether injury biomarkers,…2015 American Transplant Congress
Biomarker Panel Profile for Identification of High-Risk Patients After Heart Transplantation
Background: The first year after cardiac transplantation is critical for transplant survival and long-term outcome. Identification of suitable biomarkers for detection of rejection processes is…2015 American Transplant Congress
Inflammatory Profiling of Hypothermic Machine Pumped Kidney Allografts
Medicine, University of California, San Diego, La Jolla, CA.
Background:Pulsatile Hypothermic Machine Perfusion (MP) offers an opportunity to define inflammatory molecules generated during renal ischemia. This study reports on allografts pumped at our OPO,…2015 American Transplant Congress
CD8 T Cell Biomarkers Improves the Capacities of the Kidney Transplant Failure Score for the Long-Term Prognostic of Kidney Graft Failures
Background. Kidney transplantation is acknowledged as the treatment of choice for patients in end-stage renal disease compared to dialysis. We hypothesized that the efficiency of…2015 American Transplant Congress
Biopsychronology: Live Confocal Imaging of Biopsies to Assess Organ Function
Methods to monitor the status of a graft prior to transplantation are highly desirable to avoid unnecessary clinical interventions and to optimize the clinical outcome…
American Transplant Congress abstracts