ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    The Impact of Center Size on Outcome of Pancreas Transplants

    A. Gruessner,1 R. Gruessner.2

    1Colllege of Pubkic Health, University of Arizona, Tucson, AZ; 2Department of Surgery, University of Arizona, Tucson, AZ.

    Introduction: The number of pancreas transplants (PxTx) has continuously declined over the last decade. Since the number of transplant centers that perform pancreas transplants has…
  • 2015 American Transplant Congress

    Management of Pancreas Graft Splenic Vein Thrombosis: Is Conservative Management Safe?

    J. Harbell,1 T. Morgan,2 V. Feldstein,2 G. Roll,1 A. Posselt,1 S.-M. Kang,1 S. Feng,1 R. Hirose,1 C. Freise,1 P. Stock.1

    1Surgery, University of California, San Francisco, San Francisco, CA; 2Radiology, University of California, San Francisco, San Francisco, CA.

    Background: Prophylaxis for graft portal/splenic venous thrombosis following pancreas transplant varies between institutions. Similarly, treatment of venous thrombosis ranges from early re-exploration to conservative management…
  • 2015 American Transplant Congress

    The Role of the Incretin Effect After Pancreas Transplantation

    S. Mittal,1 R. Franklin,1 E. Sharples,1 F. Knop,2 J. Holst,2 S. Gough,1 P. Friend.1

    1Oxford University Hospital, Oxford, United Kingdom; 2University of Copenhagen, Copenhagen, Denmark.

    AIM: The ability to generate a greater insulin response to an oral compared to an intravenous glucose load is the result of pancreatic stimulation by…
  • 2015 American Transplant Congress

    Immunosuppression and Reoperation After Simultaneous Kidney Pancreas Transplantation Convey Greatest Risk for Rejection

    C. Bratton, V. Rohan, S. Nadig, J. Mcgillicuddy, K. Chavin, P. Baliga, D. Taber.

    MUSC, Charleston, SC.

    Background: Episodes of acute cellular rejection (ACR) convey significant morbidity after simultaneous kidney and pancreas transplantation (SPK). The role of recipient sensitization, immunosuppression (IS) and…
  • 2015 American Transplant Congress

    Association of IP-10 With Poor Islet Graft Function After Total Pancreatectomy With Islet Autotransplantation

    M. Kanak,1 M. Lawrence,2 F. Kunnathodi,2 G. Yoshimatsu,2 R. Shahbazov,2 M. Takita,2 M. Levy,3 B. Naziruddin.3

    1Institute for Biomedical Studies, Baylor University, Waco, Tx; 2Islet Cell Laboratory, Baylor Research Institute, Dallas, TX; 3Baylor Annette C. and Harold C. Simmons Transplant Institute, Dallas, TX.

    Introduction: Total pancreatectomy with islet autotransplantation (TPIAT) is an effective treatment for refractory chronic pancreatitis. The mechanisms underlying islet graft loss, however, remain unclear. Interferon…
  • 2015 American Transplant Congress

    Increased Use of Donors After Cardiac Death (DCD) in Pancreas Transplantation: A Safe and Effective Way to Increase a Single Center Program Activity

    M. Marquez, G. Sapisochin, J. Laurence, A. Barbas, M. Dib, A. Norgate, M. Selzner, P. Greig, I. McGilvray, M. Cattral.

    Multi-Organ Transplant, University Health Network, Toronto, ON, Canada.

    The SRTR database shows that DCD donors are rarely used for pancreas transplantation in the USA (< 3% in 2010 -2012). This low rate likely…
  • 2015 American Transplant Congress

    Outcomes of Simultaneous Pancreas and Kidney Transplantation With a High Level of Preformed Antibodies

    H. Sharma, A. El-Bakry, V. Venkat, S. Papachristos, R. Dhanda, D. Van Dellen, T. Campbell, T. Augustine, R. Pararajasingam, A. Tavakoli, B. Forgacs.

    Transplant Surgery, Manchester Royal Infirmary, Manchester, United Kingdom.

    BACKGROUND:There is paucity of data of outcomes of simultaneous pancreas and kidney transplantation in recipients with preformed antibodies. Newer induction agents have been used with…
  • 2015 American Transplant Congress

    Sirolimus Based Maintenance Immunosuppression in Pancreas Transplant Recipients

    A. Rajab, R. Pelletier, E. Elkhammas, G. Bumgardner, A. El-Hinnawi, M. Henry.

    Surgery, The Ohio State University, Columbus, OH.

    The present study evaluated the outcome of a Sirolimus based maintenance immunosuppressive protocol in pancreas transplant recipients. Between August 2003 and December 2013, a total…
  • 2015 American Transplant Congress

    Safety and Efficacy of Conversion from Conventional Twice Daily Tacrolimus to Once Daily Extended Release Tacrolimus in Stable Pancreas Transplant (SPK and PAK) Recipients

    M. Dib, A. Barbas, M. Marquez, J. Laurence, G. Sapisochin, A. Norgate, J. Schiff, I. McGilvray, P. Greig, M. Selzner, M. Cattral.

    Surgery, Multi-Organ Transplant, Toronto General Hospital, Toronto, ON, Canada.

    Background: A once-daily, modified-release oral formulation of tacrolimus has been developed to simplify dosing and improve medication adherence. There is limited data on the implementation…
  • 2015 American Transplant Congress

    Inadequate Overall Immunosuppression Is a Risk for Late Acute Rejection Despite Alemtuzumab Induction in Simultaneous Pancreas Kidney Transplant Recipients

    J. Bank,1 M. Mallat,1 P. van der Boog,1 D. Braat,2 J. Ringers,2 M. Vergunst,3 S. Heidt,3 F. Claas,3 M. Reinders,1 J. de Fijter.1

    1Nephrology, LUMC, Leiden, Netherlands; 2Surgery, LUMC, Leiden, Netherlands; 3IHB, LUMC, Leiden, Netherlands.

    Introduction: Simultaneous pancreas-kidney transplantation (SPK) has become the treatment of choice for patients with end-stage renal disease due to Type 1 Diabetes Mellitus. SPK is…
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