Abstracts Archive - Page 146 of 1683 - ATC Abstracts

2022 American Transplant Congress
The Trajectory of Donor-Derived Cell-Free DNA (dd-cfDNA) Complements the Baseline Measurements in Heart Transplant Surveillance for Rejection
P. Shah¹, R. Cheng², H. Eisen³, B. D. Lowes⁴, L. Lourenco Jenkins⁵, Y. Fu⁵, K. Qu⁵, J. Teuteberg⁶, E. DePasquale⁷
¹Inova Heart and Vascular Institute, Falls Church, VA, ²University of Washington Heart Institute, Seattle, WA, ³Pennsylvania State University, Hershey, PA, ⁴University of Nebraska Medical Center, Omaha, NE, ⁵CareDx, Brisbane, CA, ⁶Stanford University, Stanford, CA, ⁷University of Southern California, Los Angeles, CA
*Purpose: Changes in dd-cfDNA levels over time may identify patients with evolving alloimmune injury, providing complementary information to the donor fraction. We explored the dd-cfDNA…
2022 American Transplant Congress
The Prevalence of Anti-SARS-CoV-2 Antibodies After COVID-19 is Similar in Kidney Transplant Recipients to Non-Transplanted Patients, and the Clinical Severity is a Predictor of Seroconversion
L. R. Requião-Moura, R. Garcia, M. R. Nakamura, R. D. Foresto, V. Gomes, T. Ferreira, I. Meira, M. Cristelli, M. Jesus, R. Rissoni, E. Lucena, H. Tedesco-Silva, J. Medina-Pestana
Nephrology Division - Hospital do Rim, Universidade Federal de São Paulo, São Paulo, Brazil
*Purpose: To evaluate the seroconversion rate in kidney transplant recipients (KTR), compared to two non-transplanted groups of patients, and identify predictors of seroconversion in COVID-19…
2022 American Transplant Congress
Computer vs Human-Based Prediction and Stratification of the Risk of Long-Term Kidney Allograft Failure
G. Divard¹, M. Raynaud¹, V. Tataputii², B. Abdalla³, C. Legendre¹, C. Lefaucheur¹, O. Aubert¹, A. Loupy¹
¹Paris Transplant Group, Paris, France, ²NYU Langone Health, New York, NY, ³UCLA, Los Angeles, CA
*Purpose: Clinical decision-making process after transplantation is mainly driven by patient individual risk of allograft failure prediction assessed by physicians. However, this task remains difficult…
2022 American Transplant Congress
Recipient Race Modifies the Association Between Obesity and Long Term Graft Outcomes After Renal Transplantation
F. Jarrar¹, K. Tennankore², A. J. Vinson³
¹Dalhousie University, Halifax, NS, Canada, ²Nova Scotia Health Authority, Halifax, NS, Canada, ³Nova Scotia Health Authority Division of Nephrology, Departm, Halifax, NS, Canada
*Purpose: Both donor and recipient obesity are associated with adverse outcomes after transplant. Whether obesity, defined using body mass index (BMI), has different implications on…
2022 American Transplant Congress
A Single-Centre Study on the Diagnosis and Management of Transplant Ureteric Strictures: An 11 Year Experience
W. G. Norton¹, E. Aitken¹, M. Clancy², E. Murio¹, K. Gillis¹
¹Department of Renal Transplantation, NHS Greater Glasgow and Clyde, Glasgow, United Kingdom, ²NHS Greater Glasgow and Clyde, Glasgow, United Kingdom
*Purpose: The optimal management of transplant ureteric stricture is unclear. This study presents a single-centre's 11-year experience of the diagnosis and management of these cases.*Methods:…
2022 American Transplant Congress
Marginal Zone B Cells Support T Cell Reconstitution Following ATG Lymphoablation in Heart Allograft Recipients.
Y. Yamamoto, R. Fan, M. Nicosia, V. Gorbacheva, R. Fairchild, A. Valujskikh
Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH
*Purpose: Lymphoablation with anti-thymocyte globulin (ATG) is a common therapy in solid organ transplantation. However homeostatic proliferation of pre-existing memory T cells undermines the graft-prolonging…
2022 American Transplant Congress
Early Tacrolimus Exposure is Associated with BK-Viremia in Kidney Transplant Recipients
S. Meziyerh, A. L. van Rijn, D. van der Helm, P. J. van der Boog, T. van Gelder, A. C. Kroes, J. W. de Fijter, D. J. Moes, J. I. Rotmans, M. C. Feltkamp, A. P. de Vries
LUMC, Leiden, Netherlands
*Purpose: There is scant evidence to what extent maintenance immunosuppression is quantitatively associated with BK viremia. We investigated the association between tacrolimus (tac) whole blood…
2022 American Transplant Congress
Prebiotic Supplementation In Kidney Transplant Recipients For Preventing Infections And Gastrointestinal Upset: A Randomized Controlled Feasibility Study
S. Chan¹, C. M. Hawley¹, E. M. Pascoe², C. Z. Cao², S. B. Campbell², K. L. Campbell³, R. S. Francis², R. Hale¹, N. M. Isbel⁴, M. Morrison⁵, D. W. Johnson²
¹Department of Nephrology, Princess Alexandra Hospital, Woolloongabba, Australia, ²Princess Alexandra Hospital, Woolloongabba, Australia, ³Menzies Health Institute - Molecular Basis of Disease Research Program, Griffith University, Brisbane, Australia, ⁴Princess Alexandra Hospital, Brisbane, Australia, ⁵Diamantina Institute, Faculty of Medicine, The University of Queensland, Woolloongabba, Australia
*Purpose: Modulating the large intestinal microbiome of kidney transplant recipients (KTR) may reduce infectious complications. The aim of this study was to assess the feasibility…
2022 American Transplant Congress
Understanding The Modification Of Eplet Mismatch Risk By Immunosuppression Regimen
A. Johnson¹, X. Zhang¹, L. Gragert², C. Larsen¹
¹Emory University School of Medicine, Atlanta, GA, ²Tulane University School of Medicine, New Orleans, LA
*Purpose: Solid organ transplant donor-recipient eplet mismatch has been correlated with subsequent donor specific antibody (DSA) formation, antibody mediated rejection, and overall rejection rates. However,…
2022 American Transplant Congress
Superiority of Renal Transplantation in ESRD Management Over Long Term Dialysis in Octogenerians
s. karhadkar, J. Kolansky, K. Wirshup, A. Gregor, J. Dawes, A. DiCarlo
Temple University Hospital, Philadelphia, PA
*Purpose: In the last 2 decades there has been an increase in the number of patients aged 65 years and older who were placed on…