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American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    HLA Matching Affects Patient Survival, Graft Survival, and Incidence of Rejection Episodes in Largest Analysis to Date

    J. Weiner, Z. Cui, S. Mohan, E. Verna, A. Griesemer, J. Emond.

    Columbia Center for Liver Disease and Transplantation, New York Presbyterian-Columbia University Medical Center, New York, NY.

    Introduction: Though human leukocyte antigen (HLA) matching between donor and recipient affects both graft and patient survival after kidney and heart transplantation, prior analysis has…
  • 2015 American Transplant Congress

    National Outcomes of Donation After Cardiac Death (DCD) Liver Transplantation Are Equivalent to Donation After Brain Death (DBD) Liver Transplantation Using Older (DBD) Donor Livers

    R. Redfield, M. Rizzari, J. Scalea, L. Fernandez, A. D'Alessandro, J. Mezrich, D. Foley.

    University of Wisconsin, Madison, WI.

    Background: Multiple studies have demonstrated that outcomes of DCD liver transplantation (LTx) are inferior to DBD LTx. Thus DCD liver transplantation represents only 7% of…
  • 2015 American Transplant Congress

    The Donor Risk Index Does Not Accurately Classify Patients With or Without Graft Failure

    E. Franco,1 T. Athanasios,2 N. Kemmer,3 L. Leone,1 A. Alsina,1 B. Djulbegovic.2

    1Surgery, TGMG/USF Morsani College of Medicine, Tampa, FL; 2Internal Medicine, Morsani College of Medicine, USF, Morsani College of Medicine, Tampa, FL; 3Hepatology, TGMG/USF Morsani College of Medicine, Tampa, FL.

    In liver transplantation assessing risk of donor is paramount to graft survival. The donor risk index (DRI) was introduced as a predictor of graft failure…
  • 2015 American Transplant Congress

    Induction Therapy With either Anti-Thymocyte Antibodies or Il2 Receptor Inhibitors Appears to Decrease the Risk of Graft Loss in DCD Liver Transplantation Compared to No Induction Therapy

    S. Rayhill, J. Haldorson, A. Dick, S. Nazarian, L. Sibulesky, M. Montenovo, L. Yu, I. Javid, T. Pearson, R. Bakthavatsalam, P. Healey, J. Perkins, J. Reyes.

    University of Washington, Seattle.

    An analysis of our center's outcomes in DCD liver transplants suggested that induction with anti-thymocyte antibody preparations (ATG) may reduce the risk of graft loss…
  • 2015 American Transplant Congress

    Historical Comparison of Projected and Observed Liver Transplants

    J. Pyke,1 D. Schladt,1 W. Kim,5 S. Leppke,1 J. Lake,4 S. Gentry,2,3 D. Segev,2 A. Israni,1 J. Snyder.1

    1SRTR, Minneapolis Medical Research Foundation, Minneapolis, MN; 2Surgery, Johns Hopkins University School of Medicine, Baltimore, MD; 3Mathematics, US Naval Academy, Baltimore, MD; 4Medicine and Surgery, University of Minnesota Medical School, Minneapolis, MN; 5School of Medicine, Stanford University, Stanford, CA.

    We aimed to compare liver transplant simulation projections to observed data before and after a major policy update. The current liver simulated allocation model (LSAM…
  • 2015 American Transplant Congress

    Descriptive Analysis of Patients Who Travel Away from Home for Orthotopic Liver Transplantation

    C. Frenette,1 A. Harper,3 J. Waalen,2 J. Fisher,1 R. Schaffer,1 A. Baquerizo,1 C. Marsh.1

    1Department of Organ Transplant, Scripps Clinic/Green Hospital, La Jolla, CA; 2Department of Molecular & Experimental Medicine, The Scripps Research Institute, La Jolla, CA; 3United Network for Organ Sharing, United Network for Organ Sharing, Richmond, VA.

    Aim: Given the current geographic disparities in access to liver transplantation (OLT), there is a segment of the population that may travel to different areas…
  • 2015 American Transplant Congress

    Racial Disparities in Living Donor Liver Transplantation

    Y. Nobel,1 K. Forde,2 L. Wood,3 P. Yoo,4 P. Abt,3 D. Goldberg.2

    1Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; 2Department of Medicine, University of Pennsylvania, Philadelphia, PA; 3Division of Transplant Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, PA; 4Department of Surgery, Yale University School of Medicine, New Haven, CT.

    Purpose: Living donor liver transplantation (LDLT) is an alternative to deceased donor transplantation (DDLT), and can mitigate the risk of dying while waiting for transplant.…
  • 2015 American Transplant Congress

    Liver Transplantation in Children Using Organ Donation After Circulatory Death– An Analysis of the National Registry

    G. El-Gazzaz, K. Hashimoto, M. Fujiki, T. Daigo, C. Quintino, F. Aucejo, D. Kelly, C. Winans, C. Miller, J. Fung, B. Eghtesad.

    Liver Transplant and Hepatobiliary, Cleveland, Cleveland, OH.

    The waiting list mortality rate for children is higher than for adults owing to scarce availability of size-appropriate grafts for liver transplantation(OLT). There is a…
  • 2015 American Transplant Congress

    In House Oxygen Persufflation of Cold Stored Livers Versus Simple Cold Storage in Extended Criteria Liver Grafts: Results of a Randomized Controlled Clinical Trial

    A. Gallinat,1 A. Paul,1 D. Hoyer,1 C. Klein,1 S. Swoboda,1 C. Ose,2 Z. Mathe,1 J. Treckmann,1 T. Minor.3

    1Dept. of General-, Viszeral- und Transplantation Surgery, University Hospital Essen, Essen, Germany; 2Institute of Computer Science in Medicine, Biostatistics and Epidemiology, University Hospital Essen, Essen, Germany; 3Surgical Research Div., Universiy Clinic Surgery, Bonn, Germany.

    Two hours of end-ischemic oxygen persufflation of cold stored porcine livers regenerates cellular energy dependent pathways and improves survival after transplantation. The present trial evaluated…
  • 2015 American Transplant Congress

    The Impact of Ischemia/Reperfusion Injury On Liver Allografts from Deceased After Cardiac Death Versus Deceased After Brain Death Donors

    B. Sayed, J. Xu, A. Casas-Ferreira, P. Srinivasan, N. Heaton, Y. Ma, C. Legido-Quigley, S. Fuggle, W. Jassem.

    1Liver Transplant Unit, Institute of Liver Studies, King's College Hospital, London, United Kingdom; Department of Transplant Surgery, Emory University, Atlanta, United Kingdom; Institute of Pharmaceutical Science, King's College Hospital, London, United Kingdom; Department of Analytical Chemistry, University of Salamanca, Salamanca, Spain; Nuffield Department of Surgery, University of Oxford, Oxford, United Kingdom.

    Background and Aims:The shortage of appropriate organs for transplantation has led to the use of organs from donors after cardiac death. The pathophysiologic processes associated…
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