ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    The Use of Bortezomib for Desensitization in ABO Incompatible and Positive Crossmatch Kidney Transplant

    J. Benken,1 S. Akkina,2 E. Benedetti.3

    1Pharmacy Practice, Univ. of IL-Chicago, Chicago, IL; 2Dept. of Medicine, Nephrology, Univ. of IL-Chicago, Chicago, IL; 3Dept. of Surgery, Univ. of IL-Chicago, Chicago, IL.

    Introduction:ABO incompatible (ABOi) and positive crossmatch (PXM) living donor kidney transplantation is a life-saving alternative to dialysis. A variety of protocols exist utilizing plasmapheresis (PP)…
  • 2015 American Transplant Congress

    Post-Transplantation Immunoadsorption Can Be Safely Withheld After ABO-Incompatible Kidney Transplantation

    A. de Weerd,1 M. van Agteren,1 J. Ijzermans,2 W. Weimar,1 M. Betjes.1

    1Nephrology and Kidney Transplantation, Erasmus Medical Center, Rotterdam, Netherlands; 2Surgery, Erasmus Medical Center, Rotterdam, Netherlands.

    Background: After ABO-incompatible kidney transplantation, postoperative plasma exchange (PE) or immunoadsorption (IA) is performed per protocol or depending on postoperative A/B-titers to prevent acute rejection.…
  • 2015 American Transplant Congress

    Desensitization Before Living Donor Kidney Transplantation in Highly Sensitized Patients

    E. De Sousa,1 I. Revuelta,1 M. Blasco,1 F. Diekmann,1 J. Cid,2 M. Lozano,2 A. Sánchez-Escuredo,1 J. Martorell,3 E. Palou,3 J. Campistol,1 F. Oppenheimer.1

    1Nephrology, Hospital Clinic Barcelona, Barcelona, Spain; 2Hemotherapy and Hemostasis, Hospital Clinic Barcelona, Barcelona, Spain; 3Immunology, Hospital Clinic Barcelona, Barcelona, Spain.

    Renal transplantation in highly sensitized patients represents a major clinical challenge leading to long periods in the waiting list. When a living donor is available,…
  • 2015 American Transplant Congress

    Pre-Transplant Desensitization Protocol and Cancer Risk in Kidney Transplantation

    I. Revuelta,1,2,3 R. Ferreira,1 C. Canha,1 P. Piselli,4 D. Verdirosi,4 V. Tubita,2 E. De Sousa,1 F. Diekmann,1,2,3 M. Lozano,2,5 J. Cid,5 E. Palou,6 J. Martorell,6 A. Alcaraz,7 D. Serraino,8 F. Oppenheimer,1,2,3 J. Campistol.1,2,3

    1Renal Transplant Unit, Department of Nephrology and Kidney Transplant, Hospital Clinic, Barcelona, Spain; 2IDIBAPS, Barcelona, Spain; 3REDinREN. Carlos III Royal Institute. Ministry of Health, Madrid, Spain; 4Dipartamento di Epidemiologia e Ricerca Pre-Clinica, INMI “L. Spallanzani” IRCCC, Rome, Italy; 5Hemotherapy and Hemostasis, Hospital Clinic, Barcelona, Spain; 6Department of Immunology, Hospital Clinic, Barcelona, Spain; 7Department of Urology, Hospital Clinic, Barcelona, Spain; 8IRCCS Centro di Riferimento Oncologico, Aviano, Italy.

    Introduction: Desensitization (DS) in kidney transplant is a current therapy for all cause of incompatible living donor kidney transplants (LDKT). The impact in cancer risk…
  • 2015 American Transplant Congress

    Deceased Donor HLA Antibody Incompatible Renal Transplantation Without Antibody Removal: High Incidence of Acute Rejection Reduced By T-Cell Depleting Induction Therapy

    E. Jolly,1 C. Taylor,2 H. Morgan,2 S. Peacock,2 M. Clatworthy,1 N. Torpey.1

    1Division of Renal Medicine, Department of Medicine, University of Cambridge, Cambridge, United Kingdom; 2Tissue Typing Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.

    Aims: Screening for HLA-specific antibodies (Ab) is routine for patients on kidney transplant waiting lists, and HLA antigens to which a patient has detectable Ab…
  • 2015 American Transplant Congress

    Validation of the Early Postoperative labMELD as Predictor of Outcome After Transplantation of Extended Criteria Donor Livers

    D. Hoyer,1 A. Gallinat,1 T. Minor,2 F. Saner,1 P. Kocabayoglu,1 J. Treckmann,1 A. Paul.1

    1General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany; 2Surgical Research Division, University Hospital Bonn, Bonn, Germany.

    Background:Since there is no generally accepted standard definition of early allograft dysfunction (EAD) after liver transplantation, we recently suggested postoperative labMELD as predictor for outcome…
  • 2015 American Transplant Congress

    MELD as a Predictor of Post-Transplant Survival

    X. Luo, A. Massie, A. Poon, D. Segev.

    Department of Surgery, Johns Hopkins, Baltimore.

    MELD is a reliable tool to predict liver waitlist mortality. Previous studies of MELD and post-transplant outcomes have had conflicting results.METHODS: We used generalized gamma…
  • 2015 American Transplant Congress

    Utilizing CDC High Risk Donors to Improve Outcomes in Liver Transplantation

    V. Fleetwood, J. Lusciks, M. Hertl, E. Chan.

    General Surgery, Division of Transplant Surgery, Rush University Medical Center, Chicago, IL.

    Introduction: An under-utilized demographic in liver transplantation is the CDC high-risk donor (HRD). These individuals, considered at higher risk of blood-borne diseases, contribute approximately 9%…
  • 2015 American Transplant Congress

    Grip Strength, Gait Speed, and Chair Stands Predict Sarcopenia in Male But Not Female Liver Transplant Candidates

    C. Wang, S. Feng, K. Covinsky, H. Hayssen, B. Yeh, J. Lai.

    University of California, San Francisco, San Francisco, CA.

    Background: Sarcopenia, as determined by cross-sectional skeletal muscle index (SMI), is associated with waitlist mortality in liver transplant (LT) candidates, but has limited clinical utility…
  • 2015 American Transplant Congress

    The Impact of CDC High Risk Donors on Patient and Graft Survival After Liver Transplantation

    D. Moonka, A. Yoshida, A. Taylor.

    Division of Gastroenterology, Henry Ford Health System, Detroit, MI; Transplant Institute, Henry Ford Health System, Detroit, MI; Department of Public Health Sciences, Henry Ford Health System, Detroit, MI.

    We hypothesized that CDC high risk donors (HRD) might be younger than non-HRD and have other characteristics associated with favorable outcomes after liver transplant (LT).…
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