ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Evolution of Donor-Derived Cell-Free DNA During the First Week After Surgery Predicts Renal Function Recovery After Kidney Transplantation

    D. Cucchiari1, E. Cuadrado1, E. Gonzalez1, J. Puig1, M. Ramirez-Bajo1, P. Ventura-Aguiar1, I. Revuelta2, B. Bayès1, F. Diekmann1

    1Hospital Clínic de Barcelona, Barcelona, Spain, 2Hospital Clinic de Barcelona, Barcelona, Spain

    *Purpose: Donor-derived cell-free DNA (ddcfDNA) is usually employed starting from the second week after kidney transplantation (KT), as its earlier increase can be due to…
  • 2022 American Transplant Congress

    Survey of Current Transplant Center Practices Regarding Covid-19 Vaccine Mandates in the United States

    B. E. Hippen1, D. Axelrod2, K. Maher3, R. Xi3, D. Kumar4, M. Schnitzler3, K. Lentine3

    1Head of Transplant Medicine, Fresenius Medical Care, Charlotte, NC, 2University of Iowa Transplant Clinic, Iowa City, IA, 3St. Louis University School of Medicine, St. Louis, MO, 4Ajmera Transplant Centre, Toronto, ON, Canada

    *Purpose: We surveyed current policies of transplant centers regarding a COVID-19 vaccine mandate, and rationales for or against a mandate policy.*Methods: An electronic survey was…
  • 2022 American Transplant Congress

    A Retrospective Evaluation of Organ Donation in the United States: Trends in Donors and Organ Utilization Over 15-Years

    J. A. Steggerda1, I. K. Kim2, D. Borja-Cacho1

    1Transplant Surgery, Northwestern Memorial Hospital, Chicago, IL, 2Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA

    *Purpose: The general population of the United States has changed considerably over the past 15 years. This study evaluates longitudinal changes in potential organ donors…
  • 2022 American Transplant Congress

    B Cells Fit for Germinal Center Activity Predict Response to a Third Dose of SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients

    E. A. Thompson1, A. H. Karaba1, K. Cascino1, K. Roznik1, T. Chiang1, L. Biavatti1, A. T. Abedon1, J. L. Alejo1, S. L. Klein1, J. N. Blankson1, D. S. Warren1, C. X. Qin1, J. Mitchell1, J. M. Garonzik-Wang2, B. J. Boyarsky1, D. L. Segev1, A. A. Tobian1, W. A. Werbel1, A. L. Cox1, J. R. Bailey1

    1Johns Hopkins University, Baltimore, MD, 2University of Wisconsin School of Medicine and Health, Madison, WI

    *Purpose: While SARS-CoV-2 vaccination has dramatically reduced COVID-19 severity in the general population, fully vaccinated solid organ transplant recipients (SOTRs) demonstrate reduced seroconversion and increased…
  • 2022 American Transplant Congress

    Effects of Race, Previous CoV2 Exposure and the Length and Type of Maintenance Immunosuppression on Protective Immunity to COVID19 Vaccine in Solid Organ Transplant Recipients

    A. Choudhary1, M. Lerman2, S. Khan2, J. Hunt2, A. Nikaein3, D. Calianese1, E. Kalu2, D. K. Jaijyan4, W. Honnen1, A. Pinter1

    1PHRI, Rutgers University, Newark, NJ, 2Transplant, Medical City Dallas, Dallas, TX, 3Texas Speciality, Medical City Dallas, Dallas, TX, 4pHRI, Rutgers University, Newark, NJ

    *Purpose: The diverse factors affecting the vaccine induced neutralizing antibody response in solid organ transplant recipients and their immunity against CoV2 variants are needed to…
  • 2022 American Transplant Congress

    Correlation of Non-HLA Antibodies and Biopsy-Proven Antibody-Mediated Rejection

    N. Patel, M. Kittleson, J. Patel, T. Singer-Englar, S. Kim, D. Chang, E. Kransdorf, D. Megna, J. A. Kobashigawa

    Cedars-Sinai Smidt Heart Institute, Los Angeles, CA

    *Purpose: Non-HLA antibodies are seen in heart transplantation (HTx), but the clinical significance has not been established. In many cases, non-HLA antibodies are drawn, but…
  • 2022 American Transplant Congress

    Perturbing Proteostasis to Deplete Plasma Cells

    A. Rossi1, A. Burg1, K. Roskin1, A. Shields2, R. Alloway2, E. Woodle2, D. Hildeman1

    1Cincinnati Children's Hospital, Cincinnati, OH, 2University of Cincinnati College of Medicine, Cincinnati, OH

    *Purpose: Alloantibodies play critical roles in rejection and often prevent sensitized patients from receiving life-sustaining transplants. One approach for enhancing transplantation rates and survival for…
  • 2022 American Transplant Congress

    Single-Cell RNA Sequencing Highlights the Role of Epithelial-Immune Dual Feature of Proximal Tubule Cells in BK Virus Nephropathy

    G. Huang, F. Yang, X. Chen, G. Zhao, H. Zhang, J. Luo, S. Yang, L. Zhou

    Organ Transplant Center, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China

    *Purpose: BK virus nephropathy (BKVN) may cause renal allograft dysfunction and failure. However, a specific antiviral agent for BK virus does not exist. Increasing evidence…
  • 2022 American Transplant Congress

    Post-Transplant Outcomes and Financial Burden in Donation After Cardiac Death Donor Liver Transplant After the Implementation of Acuity Circle Allocation Policy

    S. Shimada, T. Shamaa, T. Ivanics, T. Kitajima, M. Adhnan, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud, S. Nagai

    Division of Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI

    *Purpose: The use of donation after cardiac death (DCD) donor liver grafts has been increasing in many transplant centers after introducing the acuity circles (AC)…
  • 2022 American Transplant Congress

    Generation Of Insulin Producing Cells From Pancreatic Tissue With Long Standing Type 1 Diabetes

    Y. Garciafigueroa, J. B. Pollett, N. L. Thai, R. Bottino

    Imagine Pharma, Pittsburgh, PA

    *Purpose: AIPCs (Activated Islet Proliferating Cells), are a novel cell population from isolated human islets obtained using a simple culture protocol that can generate cells…
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