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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Leveraging Car T Cells To Achieve Desensitization And Enable Transplantation

    V. BHOJ

    UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

    *Purpose: Pre-existing allo-antibodies (allo-Abs), that preclude transplant due to the risk of hyperacute rejection, lead to prolonged wait times and high mortality rates. Current desensitization…
  • 2022 American Transplant Congress

    The Prevalence of Anti-SARS-CoV-2 Antibodies After COVID-19 is Similar in Kidney Transplant Recipients to Non-Transplanted Patients, and the Clinical Severity is a Predictor of Seroconversion

    L. R. Requião-Moura, R. Garcia, M. R. Nakamura, R. D. Foresto, V. Gomes, T. Ferreira, I. Meira, M. Cristelli, M. Jesus, R. Rissoni, E. Lucena, H. Tedesco-Silva, J. Medina-Pestana

    Nephrology Division - Hospital do Rim, Universidade Federal de São Paulo, São Paulo, Brazil

    *Purpose: To evaluate the seroconversion rate in kidney transplant recipients (KTR), compared to two non-transplanted groups of patients, and identify predictors of seroconversion in COVID-19…
  • 2022 American Transplant Congress

    Association Between Maintenance Immunosuppressive Regimens And Covid-19 Mortality In Kidney Transplant Recipients

    A. O. Gérard1, S. Barbosa2, D. Anglicheau3, L. Couzi4, M. Hazzan5, O. Thaunat6, G. Blancho7, S. Caillard8, A. Sicard1

    1Nephrology, Nice University Hospital, Nice, France, 2Institute of Molecular and Cellular Pharmacology, CNRS, Valbonne, France, 3Nephrology, Necker University Hospital, APHP, Paris, France, 4Nephrology, Bordeaux Pellegrin University Hospital, Bordeaux, France, 5Nephrology, Lille University Hospital, Lille, France, 6Nephrology, Edouard Herriot Hospital, Hospices civils de Lyon, Lyon, France, 7Nephrology, Nantes University Hospital, Nantes, France, 8Nephrology, Strasbourg University Hospital, Strasbourg, France

    *Purpose: Kidney transplant recipients (KTR) are at increased risk of mortality from COVID-19. We conducted a cohort study among KTR from the French Solid Organ…
  • 2022 American Transplant Congress

    A Composite Endpoint to Improve Upon the Srtr 5-Tier Rating System

    R. Formica1, K. Wang2, Y. Deng2, D. Stewart3

    1Yale School of Medicine, New Haven, CT, 2Yale School of Public Health, New Haven, CT, 3UNOS, Richmond, VA

    *Purpose: Kidney transplant program performance in the US is monitored with outcome metrics used by regulatory agencies to assess provider quality and by patients to…
  • 2022 American Transplant Congress

    Donor-Specific T Cell Senescence In Operationally Tolerant Liver Transplant Recipients

    K. Deng1, N. Tanimine2, C. Breeden3, B. Burrell3, G. Gaile3, K. Lee1, R. Matheson1, F. Qiang1, C. Rickert1, C. LeGuern1, J. Markmann1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2Department of Gastroenterological and Transplantation Surgery, Hiroshima University, Hiroshima, Japan, 3Immune Tolerance Network, Bethesda, MD

    *Purpose: Recent evidence indicates a correlation in liver transplant recipients between successful operational tolerance (OT) post immunosuppression withdrawal (ISW) with both recipient age and time…
  • 2022 American Transplant Congress

    Tissue Edema Following Hypothermic Machine Perfusion of a Small Animal Hind Limb Graft

    D. Yoeli, Y. Wang, B. Li, J. Huang, S. Jain, Z. Wang, N. Nakra, N. Limon De La Rosa, K. Rampalski, A. Su, D. Mathes, K. Washington, E. Farkash, A. Jani, C. Huang

    University of Colorado Anschutz Medical, Aurora, CO

    *Purpose: The aim of this study was to evaluate the capability of preserving a small animal hind limb graft for 24 hours with hypothermic machine…
  • 2022 American Transplant Congress

    Poor Prognosis of Proliferative Glomerulonephritis with Monoclonal IgG Deposits in Renal Allografts: A Retrospective Multicenter Study from China

    Q. Wu1, D. Liang1, X. Ni1, T. Song2, X. Wu3, M. Zhang1, J. Chen1, D. Cheng1, W. Jiqiu1

    1National Clinical Research Center of Kidney Diseases, Jinling Hospital,Nanjing University Jinling School of Medicine, Nanjing, China, 2Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China, 3Department of Urology, Henan Provincial People's Hospital; Zhengzhou University People's Hospital, Zhengzhou, China

    *Purpose: To analyze the clinicopathological characteristics, treatment efficacy and prognosis of proliferative glomerulonephritis with monoclonal IgG deposits (PGNMID) in renal allografts from multi-centers in China.*Methods:…
  • 2022 American Transplant Congress

    Early Outcomes Since Implementation of New Kidney Allocation System

    K. Shah, F. Siddiqui, P. N. Chotai, A. Logan, A. Schenk, K. Washburn, A. Limkemann

    Comprehensive Transplant Center, The Ohio State University Wexner Medical Center, Columbus, OH

    *Purpose: The new Kidney allocation system (nKAS) implemented for optimization of organ placement. Like other organ allocation systems, kidney has been redefined from donation service…
  • 2022 American Transplant Congress

    Allocation Based on Acuity Circles Decreases Waiting Time for Liver Transplant Patients

    M. H. Kim, K. Sasaki, A. Gallo, T. Pham, M. L. Melcher, S. Busque, C. Esquivel, C. Bonham

    Stanford University, Stanford, CA

    *Purpose: In February, 2020, UNOS implemented a new liver allocation system incorporating a combination of acuity based on MELD/PELD score and distance from the donor…
  • 2022 American Transplant Congress

    Enhancing Early Nerve Regeneration from Reconstruction of a Segmental Nerve Injury with Polyethylene Glycol

    A. Bernal1, C. Hinshaw1, J. Hinshaw1, C. Yang2, S. Margaux1, W. Zhang1, J. Nuelle1, C. Sabbag1, G. Bittner2, J. Shores3, E. Weitzel1, J. Alderete1

    1RESTOR FUSE Nerve Reconstruction Consortium, US Army Institute of Surgical Research/59th MDW, San Antonio, TX, 2University of Texas at Austin, Austin, TX, 3John Hopkins University, Baltimore, MD

    *Purpose: Despite advancements in understanding and treating peripheral nerve injuries (PNIs), restoration of lost motor and sensory functions remain poor using current methods of clinical…
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