2015 American Transplant Congress
Infusion of Human Factor 7a Restores Circulating Platelets and Prevents TMA in Pig-to-Baboon Liver Xenotransplantation
Background We sought to determine the effects of exogenous administration of human coagulation factors in a pig-to-baboon model of liver xenotransplantation (LXT).Methods LXT was performed…2015 American Transplant Congress
Cardiac Xenotransplantation: Reconstituted B Cells After Rituxan Treatment Maintain Their Repertoire But Have a Muted Response to Xenoantigens
1CSRP/NIH/NHLBI, NIH, Bethesda, MD; 2DVR/ORS, NIH, Bethesda, MD; 3Revivicor Inc, Blacksburg, VA.
Background: Xentoranplantation (XTx) remains an option for end stage organ failure. Recently we have reported cardiac xenograft survival of over one year pig to baboon…2015 American Transplant Congress
Immunological Evaluation of Acellular Extracellular Matrix Upon Transplantation
Background : To mitigate the scanty supply of donor organs, porcine tissues can be utilized since, it embrace the potential to accomplish the task of…2015 American Transplant Congress
Immunomodulatory Strategies Directed Towards Tolerance of Vascularized Composite Allografts
Background: Achieving tolerance of vascularized composite allografts (VCAs) would improve the risk-to-benefit ratio in patients who undergo this life-enhancing transplant. Kidney co-transplantation along with a…2015 American Transplant Congress
Costimulation Blockade Prevents Rejection of Vascularized Composite Allografts
[Background] Vascularized composite allotransplantation (VCA) is an emerging new era in transplant medicine and has become a valid therapeutic option after devastating tissue loss. The…2015 American Transplant Congress
Effects of Immunosuppressives On Porcine Renal Microvascular Endothelial Cell–Activated Human T Cell Proliferation: A Cellular Model of Kidney Xenotransplantation In Vitro
Surgery, Indiana University School of Medicine, Indianapolis, IN.
Background: The creation of genetically-modified pigs has brought us closer than ever to clinical xenotransplantation. However, the optimal immunosuppressive doses still need to be established…2015 American Transplant Congress
Is Ex Vivo Liver Perfusion a Safe Alternative to Cold Static Storage for the Preservation of Standard Criteria Grafts?
Multi Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada.
Objective: Subnormothermic ex vivo liver perfusion (SNEVLP) has recently attracted great interest in the field of organ preservation for marginal grafts. However, data is lacking…2015 American Transplant Congress
Experimental Study Using Contrast-Enhanced Ultrasonography to Evaluate Rat Chronic Allograft Nephropathy Model and the Relationship Between Hemodynamic Parameters and Renal Allograft Fibrosis
Objectives:To quantitatively analyze the changes of hemodynamic characteristics in renal allograft at different stages of a rat chronic allograft nephropathy [CAN]model and the relationship between…2015 American Transplant Congress
Immune Phenotyping of Peripheral Blood Samples from the CTOT-10 Belatacept Study
The purpose of the CTOT-10 study is to evaluate belatacept as maintenance therapy, while minimizing calcineurin inhibitors and corticosteroids in renal transplantation. We designed mechanistic…2015 American Transplant Congress
The Association of Basiliximab and Antithymocyte Globulin Induction With Delayed Graft Function
The impact of selection of induction immunosuppression agent on incidence of delayed graft function (DGF) remains unclear. A total of 1,980 deceased donor kidney transplant…
American Transplant Congress abstracts