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American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Long Term Survival After Single Versus Double Lung Transplantation in Patients With Pulmonary Fibrosis in the Modern Era of the Lung Allocation Score

    V. Ambur, S. Jayarajan, S. Taghavi, S. Kadakia, C. Lewis, Y. Furuya, A. Shiose, L. Kaiser, G. Wheatley, T. Guy, Y. Toyoda.

    Surgery, Temple University Hospital, Philadelphia, PA.

    Objectives: To examine long-term survival in patients with idiopathic pulmonary fibrosis (IPF) after the implementation of the lung allocation score (LAS) in single lung transplantation…
  • 2015 American Transplant Congress

    The Preservation Technique Modulates the Immunological Milieu in Lung Transplantation and Affects the Pro-/ Anti-Inflammatory Balance

    M. Seyda,1 B. Wiegmann,3 B. Mueller,2 C. Neudoerfl,1 A. Akhdar,1 K. Daemen,1 A. Haverich,3,4 G. Warnecke,3,4 C. Falk.3,5

    1Inst. of Transplant Immunology, IFB-Tx, Hanover Medical School, Hanover, Germany; 2MorphoSys, Munich, Germany; 3Cardiothoracic, Transplantation and Vascular Surgery, Hanover Medical School, Hanover, Germany; 4German Center for Lung Research, Gießen, Germany; 5German Center for Infection Research, Braunschweig, Germany.

    Little is known regarding the influence of different preservation techniques (i.e. cold static storage with Perfadex® or Celsior® solution) on the immunological milieu, especially lung-resident…
  • 2015 American Transplant Congress

    Lung Transplantation (LTx) in Patients on Extracorporeal Support – Is It a Bridge Too Far? A Single Centre Cohort Analysis

    B. Zych, D. Garcia-Saez, P. Mohite, A. Reed, F. De Robertis, A. Popov, M. Amrani, T. Bahrami, N. Patil, M. Carby, A. Simon.

    Department of Cardio-Thoracic Transplantation & Mechanical Circulatory Support, Harefield Hospital. Royal Brompton & Harefield NHS Foundation Trust, Harefield, Middlesex, United Kingdom.

    Objective: LTx in patients remaining on extracorporeal support is still controversial approach despite good results published by leading transplant centres. In this study we evaluate…
  • 2015 American Transplant Congress

    Extracorporeal Life Support: A Rescue Therapy in a Lung Transplantation Program

    P. Mohite, D. Gacia-Saez, B. Zych, N. Patil, M. Zeriouh, A. Koch, A.-F. Popov, A. Reed, M. Carby, F. DeRobertis, T. Bahrami, M. Amrani, S. Penn, S. Silver, S. Soresi, A. Simon.

    Department of Cardiothoracic Transplantation & Mechanical Circulatory Support, Harefield Hospital, Royal Brompton and Harefield NHS Foundation Trust, London, Middlesex, United Kingdom.

    Purpose: Extracorporeal Life Support (ECLS) is increasingly used as a bridge to lung transplantation (LTx) as well as in the management of severe primary graft…
  • 2015 American Transplant Congress

    CYP3A4 Polymorphisms Correlate With Time to Achieve Tacrolimus Steady State Concentration in Lung Transplant Patients

    I. Timofte, A. Iacono, J. Kim, P. Sanchez, R. Reed, K. Rajagopal, M. Mclenon, B. Griffith, R. Pierson, S. Pham.

    Pulmonary and Critical Care, University of Maryland, Baltimore; Surgery, University of Maryland, Baltimore.

    Introduction:Tacrolimus is the main component of the immunosuppressive regimen used in patients with solid organ transplants. Tacrolimus requires blood concentration monitoring due a narrow therapeutic…
  • 2015 American Transplant Congress

    Bortezomib-Based Multi-Modality Protocol for Donor-Specific Antibody Treatment in Lung Transplant Recipients

    M. Vacha, A. Hulbert, J. Byrns, C. Benedetti, A. Finlen Copeland, A. Gray, S. Palmer, L. Snyder.

    Duke University Hospital, Durham, NC.

    Background Donor specific antibodies (DSAs) after lung transplant have been implicated in the development of chronic lung allograft dysfunction and mortality. The ideal treatment strategy…
  • 2015 American Transplant Congress

    Operating Room Extubation After Bilateral Lung Transplantation in Cystic Fibrosis Patients: A Single Center Experience

    M.-L. Felten,1 J.-D. Moyer,1 J.-Y. Marandon,1 J.-F. Dreyfus,2 M. Fischler.1

    1Anesthesiology Department, Foch Hospital, Suresnes, Hauts-de-Seine, France; 2Research and Innovation Department, Foch Hospital, Suresnes, Hauts-de-Seine, France.

    Short-acting anesthetic drugs, thoracic epidural analgesia and a strict ventilation weaning protocol could permit extubation in the operating room (OR) (1). Aims of this study…
  • 2015 American Transplant Congress

    Pretransplant Panniculectomy in Patients Previously Denied Access to Renal Transplantation: Addressing Disparities for Candidates With a High-Risk Abdominal Panniculus After Weight Loss

    C. Troppmann,1 C. Bailey,2 J. Kuo,2 C. Santhanakrishnan,1 R. Perez,1 M. Wong.2

    1Transplant Surgery, UC Davis, Sacramento, CA; 2Plastic Surgery, UC Davis, Sacto..

    Some patients (pts) develop a large lower abdominal panniculus following significant weight loss (worsened by age and abdominal wall laxity). CKD pts affected by this…
  • 2015 American Transplant Congress

    Obesity: A Major Risk Factor for Wound and Parietal Complications in Renal Transplantation

    H. Andrade, W. Nahas, R. Kato, K. Yamaçake, H. Kanashiro, I. Antonopoulos, A. Bull, R. Falci, A. Piovesan.

    Division of Urology, Renal Transplantation Unit, University of Sao Paulo, Sao Paulo, Brazil.

    Purpose: The increase of obesity among patients with end-stage renal disease poses a major challenge for urologists and nephrologists. Many centers set an upper limit…
  • 2015 American Transplant Congress

    The Impact of Donor and Recipient Weight Incompatibility on Outcomes in Renal Transplantation

    L. Wong,1 S. Moran,1 A. Counihan,2 P. Cunningham,2 P. O'Kelly,1 P. Conlon.1

    1Nephrology, Beaumont Hospital, Dublin, Ireland; 2Urology and Transplantation, Beaumont Hospital, Dublin, Ireland.

    Background: Kidney transplantation has been proposed as an accelerated model of nephron reduction resulting from the accumulation of repeated insults, both immunologic and non-immunologic events.…
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