Abstracts Archive - Page 140 of 1683 - ATC Abstracts

2022 American Transplant Congress
Toll-Like Receptor-4 Inhibitor, Resatorvid, Attenuates Allogenic T Cell Activation Against Human Pancreatic Islets by Decreasing CD69 Expression
J. Mattke¹, M. Plunk¹, R. R. Kane¹, B. Naziruddin²
¹Baylor University, Waco, TX, ²Baylor University Medical Ctr, Dallas, TX
*Purpose: Allogenic and autoimmune response against islets remain major obstacles to improve long term function of islet transplants. Inhibition of toll-like receptor 4 (TLR4) using…
2022 American Transplant Congress
Impact of Removing DSA and OPTN Region from Pancreas Allocation
S. E. Booker¹, A. Robinson¹, K. Gauntt¹, J. White¹, S. Niederhaus², O. Olaitan³, R. Forbes⁴
¹UNOS, Richmond, VA, ²University of Maryland School of Medicine, Baltimore, MD, ³Rush University Medical Center, Chicago, IL, ⁴Vanderbilt University Medical Center, Nashville, TN
*Purpose: Donation Service Area (DSA) and OPTN Region were removed from pancreas allocation on 3/15/21 and replaced with a 250 nautical mile (NM) fixed circle…
2022 American Transplant Congress
Bacterial Infections After Kidney Transplant Before and After the COVID-19 Pandemic
A. Perez Gutierrez¹, B. Juengel¹, S. Krishnamoorthy², P. J. Bachul¹, P. Witkowski³, R. Barth³, J. Fung¹
¹Department of Surgery, University of Chicago Medicine, Chicago, IL, ²Department of Medicine, University of Chicago Medicine, Chicago, IL, ³University of Chicago Medicine, Chicago, IL
*Purpose: Infectious complications are a major cause of mortality and morbidity after kidney transplantation. During the COVID-19 pandemia there were several changes in the management…
2022 American Transplant Congress
Favorable Outcomes in Older Recipients Receiving Simultaneous Kidney Pancreas Transplantation
P. Budhiraja¹, H. Me¹, J. Ninan², S. Reddy², s. S. Misra¹, R. Heilman¹, H. Khamash¹, K. Reddy¹, C. Jadloweic¹, N. Katariya¹, H. Chakkera¹
¹Mayo Clinic, Phoenix, AZ, ²Mayo Clinic, Rochester, MN
*Purpose: Improved therapeutic advances in diabetes mellitus care have resulted in a higher number of older diabetics on dialysis. The majority of centers use an…
2022 American Transplant Congress
Cryptococcal Meningitis Presenting as SIADH in a Heart Transplant Recipient
D. Blake, M. Ibrahim, E. Hamad, V. Rakita, J. Hoosain, H. Clauss
Temple University Hospital, Philadelphia, PA
*Purpose: Cryptococcal meningitis is a potentially fatal invasive fungal infection in solid organ transplant recipients. Meningoencephalitis is the most common clinical manifestation of cryptococcal infection.…
2022 American Transplant Congress
Donor Kidney-Resident Passenger Macrophages Promote CCL8-CCR8 Mediated Early Allograft Inflammation
A. Dangi¹, I. Husain², N. Natesh³, X. Shen³, J. Kwun⁴, X. Luo⁵
¹Medicine, Duke University Medical Center, Durham, NC, ²Duke University Medical Center, Durham, NC, ³Biomedical Engineering, Duke University, Durham, NC, ⁴Duke Transplant Center, Durham, NC, ⁵Duke University School of Medicine, Durham, NC
*Purpose: Early intragraft infiltration of monocytes and macrophages has been associated with acute and chronic allograft rejections. Nevertheless, underlying mechanism remained poorly understood. In the…
2022 American Transplant Congress
An Interim Report on a Prospective Randomized Trial of Extended-Release Tacrolimus in Liver Transplantation with Anti-Thymocyte Induction in a Steroid Free Protocol
R. A. Helmick, S. Naik, C. Eymard, J. Eason, J. Vanatta
James D. Eason Transplant Institute at Methodist University Hospital and University of Tennessee Health Science Center, Memphis, TN
*Purpose: Our study hypothesis was that once daily dosing of extended-release tacrolimus (ERT) would be a safe and effective immunosuppression (IS) with the potential to…
2022 American Transplant Congress
Clinical Significance of the Living Kidney Donor Profile Index in Living Kidney Donors for Predicting of Post-Transplant Outcome: Korean Organ Transplantation Registry
J. Kim¹, D. Kim¹, S. Yoon¹, S. Kang¹, J. Kim¹, H. Hwang¹, K. Jeong¹, H. Ko², C. Jung³, D. Kim⁴, Y. Kim⁵, J. Yang⁶, C. Ahn⁷
¹Department of Nephrology, Kyung Hee University hospital, Seoul, Korea, Republic of, ²Department of Surgery, College of Medicine, Kyung Hee University, Seoul, Korea, Republic of, ³Department of Transplantation and Vascular Surgery, Korea University Anam Hospital, Seoul, Korea, Republic of, ⁴Department of Surgery, Yonsei University Wonju College of Medicine, Wonju Severance Christian Hospital, Wonju, Korea, Republic of, ⁵Department of Internal Medicine, Inje University Busan Paik Hospital, Busan, Korea, Republic of, ⁶Department of Surgery, Seoul National University Hospital, Seoul, Korea, Republic of, ⁷Department of Nephrology, Seoul National University Hospital, Seoul, Korea, Republic of
*Purpose: According to recent reports, a risk index for living donor kidney transplantation (LDKT) such as the Kidney donor profile index (KDPI), a non-invasive method…
2022 American Transplant Congress
Intra Portal Islet Auto Transplantation (IAT) Independently Improves Quality of Life in Patients After Total Pancreatectomy (TP) and IAT in Patients with Chronic Refractory Pancreatitis
S. Chinnakotla, G. Beilman, D. Vock, M. Freeman, V. Kirchner, T. Pruett, S. Amateau, G. Trikudanathan, E. Downs, S. Schwarzenberg, M. Armfield, K. Ramanathan, D. Sutherland, M. Bellin
University of Minnesota Medical School, Minneapolis, MN
*Purpose: TPIAT is utilized for intractable chronic-pancreatitis (CP).TP removes the source of pain and the addition of an islet auto transplant (IAT) minimizes the risk…
2022 American Transplant Congress
Stabilization of Cell-Cell Junctions Improves Outcomes in an Ex-Vivo Porcine Renal Ischemia-Reperfusion Injury Culture Model
L. Plumblee¹, K. Patel², L. Langerude³, Z. Tu³, D. Nord⁴, T. Beduschi³, S. Nadig⁵, C. Atkinson⁶
¹MUSC College of Medicine, Gainesville, FL, ²University of Virgina, Charlottesville, VA, ³University of Florida, Gaineville, FL, ⁴Division of Pulmonary, Critical Care, and Sleep Medicine, University of Florida, Gainesville, FL, ⁵Northwestern University, Charleston, SC, ⁶Pulmonary Medicine, University of Florida, Gainesville, FL
*Purpose: Renal transplant is an accepted therapy for end-stage renal failure. Chronic transplant dysfunction remains the leading cause of long-term graft loss and is, in…