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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Liver Transplant Recipient Social Support Network: Impact on Clinical Outcomes

    M. M. French1, R. S. Mangus2, R. Holmes3, A. Krause3, J. Sumner3, C. Kubal4, B. Ekser5, P. Mihaylov6, J. Fridell7, A. Lutz8

    1Social Work, Indiana University, Indianapolis, IN, 2Surgery, Indiana University, Indianapolis, IN, 3Department of Surgery, Indiana University, Indianapolis, IN, 4Department of Surgery, Indiana University Hospital, Indianapolis, IN, 5Surgery, Indiana University - Transplant Surgery, Indianapolis, IN, 6Department of Surgery, Indiana Univ School of Medicine, Indianapolis, IN, 7Indiana University School of Medicine, Indianapolis, IN, 8Department of Surgery, Indiana University, Fishers, IN

    *Purpose: Health disparities are present in transplantation, just as in other areas of medicine. This is a retrospective review of liver transplant (LT) recipients to…
  • 2022 American Transplant Congress

    Characterization of Acute Kidney Injury in Fatty Liver Ischemia Reperfusion Injury

    Z. P. Rokop, W. Zhang, N. Ghosh, A. Das, N. Biswas, C. Sen, C. Kubal

    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN

    *Purpose: The association between hepatic ischemia reperfusion injury (hIRI) and acute kidney injury (AKI) has been well established. AKI is commonly observed following transplantation of…
  • 2022 American Transplant Congress

    Recurrent Cytomegalovirus and the Role of Secondary Prophylaxis in Heart and Lung Transplant Recipients

    S. N. Finder1, K. Harrison1, M. Morrison1, S. Rega2, I. Feurer2, C. Gorsline3, G. Satyanarayana3, S. Hamel1

    1Department of Pharmaceutical Sciences, Vanderbilt University Medical Center, Nashville, TN, 2Vanderbilt Transplant Center, Nashville, TN, 3Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN

    *Purpose: This study aimed to describe the incidence of cytomegalovirus (CMV) recurrence in heart and lung transplant recipients and the effect of secondary prophylaxis (SP)…
  • 2022 American Transplant Congress

    A Third Dose of SARS-CoV-2 Vaccine Increases Neutralizing Antibodies Against Variants of Concern in Solid Organ Transplant Recipients

    A. H. Karaba1, X. Zhu1, T. Ling1, K. H. Wang1, A. G. Rittenhouse1, O. Akinde1, Y. Eby1, J. E. Ruff1, J. N. Blankson1, A. T. Abedon1, J. L. Alejo1, A. L. Cox1, J. R. Bailey1, E. A. Thompson1, S. L. Klein1, D. S. Warren1, J. M. Garonzik-Wang2, B. J. Boyarsky1, I. Sitaras1, A. Pekosz1, D. L. Segev1, A. A. Tobian1, W. A. Werbel1

    1Johns Hopkins University, Baltimore, MD, 2University of Wisconsin School of Medicine and Health, Madison, WI

    *Purpose: Vaccine-induced SARS-CoV-2 antibody responses are attenuated in solid organ transplant recipients (SOTRs) and breakthrough infections are more common. Additional SARS-CoV-2 vaccine doses increase anti-spike…
  • 2022 American Transplant Congress

    Impact of Cold Ischemia Times on 1 Year Kidney Transplant Outcomes

    T. Fletchinger, L. Burdine

    Department of Surgery, University of Arkansas for Medical Sciences, Little Rock, AR

    *Purpose: Recent organ allocation changes have increased travel and subsequent cold ischemia times (CIT) of kidney allografts. We sought to investigate the impact of prolonged…
  • 2022 American Transplant Congress

    Long-Term Kidney Allotransplant Acceptance is Defined by a Shift from a T Cell to a B Cell Rich Immune Microenvironment Within the Graft

    E. S. Szuter1, T. Yokose1, M. T. Guinn1, J. Ge2, I. Rosales3, B. Kwon4, P. S. Russell1, A. Cuenca2, D. Kreisel5, P. Sage6, J. C. Madsen1, R. B. Colvin3, A. Alessandrini1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2Department of Surgery, Boston Children's Hospital, Boston, MA, 3Department of Pathology, Massachusetts General Hospital, Boston, MA, 4Harvard College, Cambridge, MA, 5Department of Surgery, Washington University, St. Louis, MO, 6Transplantation Research Center, Renal Division, Brigham and Women’s Hospital, Boston, MA

    *Purpose: Mouse kidney allografts are spontaneously accepted in select, fully-mismatched donor-recipient strain combinations, such as DBA/2J to C57BL/6 (B6). Tolerant renal grafts develop aggregates of…
  • 2022 American Transplant Congress

    COVID-19 Vaccination Induces a Poor Interleukin-21 Memory T-cell Response in Kidney Transplant Recipients

    S. R. Malahe1, Y. den Hartog1, R. de Kuiper1, D. Reijerkerk1, D. Geers2, C. H. GeurtsvanKessel2, M. M. Kho1, R. D. de Vries2, M. E. Reinders1, C. C. Baan1

    1Internal Medicine, Nephrology and Transplantation, Erasmus MC, Rotterdam, Netherlands, 2Viroscience, Erasmus MC, Rotterdam, Netherlands

    *Purpose: COVID-19-related morbidity and mortality is high among kidney patients. Several studies recently suggested low humoral and cellular immune responses after two doses of mRNA-1273…
  • 2022 American Transplant Congress

    Bioink Based on the DECM for 3D-Bioprinting of Bionic Pancreas – First Results of Animal

    M. Klak1, K. Kosowska1, T. Bryniarski1, I. Lojszczyk1, T. Dobrzanski2, G. Tymicki1, A. Filip1, A. A. Szczepankiewicz3, R. Olkowski4, A. Kosowska4, A. Berman1, A. Kaminski4, M. Wszola1

    1Foundation of Research and Science Development, Warsaw, Poland, 2Polbionica LTD, Warsaw, Poland, 3Institute of Experimental Biology M. Nencki PAN, Warsaw, Poland, 4Medical University of Warsaw, Warsaw, Poland

    *Purpose: Tissue engineering is an interdisciplinary field involving activities based on two interrelated areas: developing new methods to repair, regenerate and replace damaged tissues and…
  • 2022 American Transplant Congress

    Risk Factors for Early Post Transplant Cardiac Dysfunction After Liver Transplantation

    V. Subramanian1, K. Bowers2, H. Kalagotla2, J. Buggs1, N. Kemmer1, K. Dhanireddy1

    1Transplant Institute, Tampa General Hospital, Tampa, FL, 2University of South Florida, Tampa, FL

    *Purpose: Cardiovascular complications after liver transplantation (LTx) are a leading cause of morbidity and mortality. The goal of this study was to evaluate risk factors…
  • 2022 American Transplant Congress

    Longitudinal Mortality Risks and Renal Functional Outcomes in Living Kidney Donors

    K. Hotta1, T. Osawa1, I. Yokota2, T. Inao2, T. Tanabe1, N. Iwahara1, N. Shinohara1

    1Urology, Hokkaido University Hospital, Sapporo, Japan, 2Biostatistics, Hokkaido University Graduate School of Medicine, Sapporo, Japan

    *Purpose: Previous studies have suggested that living kidney donors do not have a higher risk of death or end-stage kidney disease (ESKD) than the general…
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