Abstracts Archive - Page 14 of 1683 - ATC Abstracts

2022 American Transplant Congress
Results Of The Ctot19 Trial: Infliximab (IFX) Induction Does Not Impact 2-year Outcomes In Deceased Donor Kidney Transplant Recipients
P. Heeger¹, B. Armstrong², T. Alhamad³, D. Brennan⁴, J. Bromberg⁵, S. Bunnapradist⁶, S. Chandran⁷, R. Fairchild⁸, D. Foley⁹, R. Formica¹⁰, I. W. Gibson¹¹, D. Hricik¹², K. Kesler², R. B. Mannon¹³, M. Menon¹⁰, K. Newell¹⁴, P. Nickerson¹¹, J. Odim¹⁵, E. Poggio⁸, R. Sung¹⁶, R. Shapiro¹, K. Tinckam¹⁷, F. Vincenti⁷
¹Mount Sinai, New York, NY, ²Rho, Durham, NC, ³Washington U, Saint Louis, MO, ⁴Johns Hopkins, Baltimore, MD, ⁵U Maryland, Baltimore, MD, ⁶UCLA, Los Angeles, CA, ⁷UCSF, San Francisco, CA, ⁸Cleveland Clinic, Cleveland, OH, ⁹U Wisconsin, Madison, WI, ¹⁰Yale, New Haven, CT, ¹¹U Manitoba, Winnipeg, MB, Canada, ¹²U Hosp Case, Cleveland, OH, ¹³U Nebraska, Omaha, NE, ¹⁴Emory, Atlanta, GA, ¹⁵NIAID NIH, Rockville, MD, ¹⁶U Michigan, Ann Arbor, MI, ¹⁷U Hlth Network, Toronto, ON, Canada
*Purpose: Ischemia-reperfusion (IR) of a kidney transplant (KTx) up-regulates tumor necrosis factor alpha (TNF) production within the allograft. IR-induced TNF amplifies post-KTx allograft inflammation and…
2022 American Transplant Congress
HLA-II Subclasses Behave Differently Between Themselves and Between Humans: Cues to Understand Alloreactivity
S. Beland, O. Desy, M. Marcoux, M. Thivierge, J. Desgagnes, S. A. De Serres
Transplantation Unit, Renal Division, University Health Center of Quebec, Faculty of Medicine, Universite Laval, Quebec, QC, Canada
*Purpose: De novo anti-HLA-II DSAs (dnDSA) are associated with antibody-mediated rejection. However, some patients with anti-HLA-II DSAs will not develop rejection, suggesting that the development…
2022 American Transplant Congress
Poor Prognosis of Proliferative Glomerulonephritis with Monoclonal IgG Deposits in Renal Allografts: A Retrospective Multicenter Study from China
Q. Wu¹, D. Liang¹, X. Ni¹, T. Song², X. Wu³, M. Zhang¹, J. Chen¹, D. Cheng¹, W. Jiqiu¹
¹National Clinical Research Center of Kidney Diseases, Jinling Hospital,Nanjing University Jinling School of Medicine, Nanjing, China, ²Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China, ³Department of Urology, Henan Provincial People's Hospital; Zhengzhou University People's Hospital, Zhengzhou, China
*Purpose: To analyze the clinicopathological characteristics, treatment efficacy and prognosis of proliferative glomerulonephritis with monoclonal IgG deposits (PGNMID) in renal allografts from multi-centers in China.*Methods:…
2022 American Transplant Congress
Intraabdominal Hypertension in the Death by Neurologic Criteria Organ Donor
C. Schardein¹, M. Moncure², S. Craft¹, S. Sanders³
¹General Surgery, University of Missouri at Kansas City, Kansas City, MO, ²Trauma and Critical Care Surgery, University of Missouri at Kansas City, Kansas City, MO, ³MTN, Kansas City, MO
*Purpose: This study attempts to identify the incidence of abdominal compartment syndrome (ACS) within the death by neurological criteria organ donor population, provide timely intervention,…
2022 American Transplant Congress
Technology Enabled And Molecular Monitoring Of The Allograft And Transplant Recipient Study
N. Sulejmani¹, D. Axelrod², S. Dholakia¹, S. Shah³
¹CareDx, South San Francisco, CA, ²University of Iowa, Iowa City, IA, ³University of Cincinnati, Cincinnati, OH
*Purpose: With the widespread availability of smart mobile devices, mobile health (mHealth) provides the opportunity to reach wide array of patients. Readmission rates as high…
2022 American Transplant Congress
Cold Ischemia Time is More Critical for Older Donor Kidney Survival: A Machine Learning Approach
J. Kim, J. Ahn, A. Massie, D. Segev, S. Bae
Johns Hopkins, Baltimore, MD
*Purpose: Increasing utilization of kidneys from older donors is a potential solution to mitigate the organ shortage. However, older donor age is a risk factor…
2022 American Transplant Congress
Evolution of the Need for Transplant Evaluations for Liver Failure Decompensation After TIPS
N. Kemmer¹, V. Sureshkumar², L. Grater³, G. Hoots⁴, S. Agrawal¹, K. Robichaux⁵, M. Gosselin³, S. Mohammed⁵, A. Kumar⁶, J. Buggs⁷
¹Transplant Hepatology, Tampa General Hospital, Tampa, FL, ²Lake Erie College of Osteopathic Medicine, Bradenton, FL, ³University of Tampa, Tampa, FL, ⁴Radiology, Tampa General Hospital, Tampa, FL, ⁵University of South Florida, Tampa, FL, ⁶Morsani College of Medicine, University of South Florida, Tampa, FL, ⁷Transplant Surgery, Tampa General Hospital, Tampa, FL
*Purpose: Portal hypertension is described as an increased pressure gradient between the portal and systemic circulation which can result in severe complications. Transjugular Intrahepatic Portosystemic…
2022 American Transplant Congress
Bionic Pancreas – 3D Bioprinting of a Bionic Organ with a Vascular System – Results of Transplantation in Large Animals
M. Wszola¹, M. Klak², A. Berman³, M. Kolodziejska¹, T. Bryniarski¹, G. Tymicki¹, T. Dobrzanski¹, D. Szkopek⁴, K. Roszkowicz-Ostrowska⁵, J. Wolinski⁵, A. Dobrzyn⁶, A. Kaminski⁷
¹Foundation of Research and Science Development, Warsaw, Poland, ²Foundation for Research and Science Development, Warsaw, Poland, ³Polbionica Ltd., Warsaw, Poland, ⁴Institute of Animal Physiology and Nutrition Jan Kielanowski of the Polish Academy of Sciences,, Jabłonna, Poland, ⁵Institute of Animal Physiology and Nutrition Jan Kielanowski of the Polish Academy of Sciences, Jablonna, Poland, ⁶Laboratory of Cell Signaling and Metabolic Disorders, Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland, ⁷Department of Transplantology and Central Tissue Bank, Medical University of Warsaw, Warsaw, Poland
*Purpose: There is lack organs for transplantation. The transplantation of the pancreas is recommended in diabetes with complications. The combination of cell biology and 3D-bioprinting…
2022 American Transplant Congress
QSant, a Novel Urine Test Monitors Recovery of Allograft Injury After DGF
S. Ghosh¹, H. Tedesco², R. Sarwal¹, N. Titzler¹, W. Yazar¹, M. Nakamura², J. Pestana², M. Sarwal¹
¹Nephrosant, Brisbane, CA, ²Hospital do Rim, Sao Paolo, Brazil
*Purpose: We evaluate urine QSant assay to non-invasively monitor recovery of allograft injury, post delayed graft function(DGF).*Methods: 65 HLA-DR matched, renal allograft recipients, on TAC/MMF/prednisone…
2022 American Transplant Congress
p40 Homodimers Stimulate Graft Dendritic Cells to Produce IL-15 Driving Endogenous Donor-Reactive Memory CD8 T Cell Activation within High-Risk Cardiac Allografts
H. Tsuda¹, A. Valujskikh², R. Fairchild³
¹Inflammation and Immunity, Cleveland Clinic, Cleveland, OH, ²The Cleveland Clinic Fdn, Cleveland, OH, ³Cleveland Clinic Foundation, Cleveland, OH
*Purpose: Acute allograft injury occurring during the first 1-2 days post-transplant is mediated by graft infiltrating endogenous donor-reactive memory CD8 T cells and requires their…