ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Diabetic Kidney Transplant Recipients: Impaired Infection Control and Alloreactivity

    T. Schachtner,1,2 M. Stein,2 P. Reinke.1,2

    1Nephrology and Internal Intensive Care, Charité Campus Virchow Clinic, Berlin, Germany; 2Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.

    New onset diabetes after transplant (NODAT) has been associated with an increased risk of infection and sepsis. Previous studies, however, failed to identify differences in…
  • 2015 American Transplant Congress

    A Randomized Study Comparing Parathyroidectomy Versus Cinacalcet to Treat Hypercalcemia in Kidney Allograft Recipients With Persistent Hyperparathyroidism

    J. Cruzado,1 V. Torregrosa,5 R. Mast,3 A. García-Barrasa,2 O. Bestard,1 E. Melilli,1 J. Francos,2 J. Torras,1 C. Polo,1 C. Gómez-Vaquero,4 J. Grinyó,1 P. Moreno.2

    1Nephrology, Hospital de Bellvitge, Barcelona, Spain; 2Surgery, Hospital de Bellvitge, Barcelona, Spain; 3Radiology, Hospital de Bellvitge, Barcelona, Spain; 4Rheumatology, Hospital de Bellvitge, Barcelona, Spain; 5Nephrology, Hospital Clínic, Barcelona, Spain.

    Purpose: Cinacalcet corrects hypercalcemia and hypophosphatemia in patients with persistent hyperparathyroidism (HPT) after kidney transplantation (KT). This study (NCT011178450) was designed to evaluate whether subtotal…
  • 2015 American Transplant Congress

    Detecting Bowel Cancer in Pre-Dialysis, Dialysis Patients and Kidney Transplant Recipients – The DETECT Study

    G. Wong, J. Chapman, J. Craig.

    University of Sydney, Sydney, NSW, Australia.

    Background: Colorectal cancer (CRC) is the third most common solid organ cancer in people living with kidney disease, and has a very poor prognosis, with…
  • 2015 American Transplant Congress

    Combination of Non-HLA and HLA-DSA Antibodies Identifies Liver Transplants Recipients With Highest Risk for Fibrosis Progression and Mortality

    J. O'Leary,1 J. Cai,2 H. Heidecke,3 L. Jennings,1 A. Philippe,4 V. Harbour,1 R. Catar,4 P. Terasaki,2 G. Klintmalm,1 D. Dragun.4

    1Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX; 2Terasaki Foundation Laboratory, Los Angeles, CA; 3Celltrend, Berlin, Germany; 4Nephrology & Intensive Care Medicine, Charite Berlin, Berlin, Germany.

    Recent data has shown an increased risk of fibrosis progression in HCV viremic liver transplant (LT) recipients with HLA DSA in serum. However, the role…
  • 2015 American Transplant Congress

    Everolimus and Early Calcineurin Inhibitor Withdrawal Is Associated With Superior Renal Function: 5-Year Follow-Up of the Randomized PROTECT Liver Transplantation Study

    M. Sterneck, G. Kaiser, N. Heyne, N. Richter, F. Rauchfuss, A. Pascher, P. Schemmer, L. Fischer, C. Klein, S. Nadalin, F. Lehner, U. Settmacher, D. Gotthardt, M. Loss, S. Ladenburger, P. Wimmer, M. Dworak, H. Schlitt.

    PROTECT Study Group, Novartis Pharma GmbH, Germany.

    Purpose: At the end of the 12-month (M) PROTECT core study (NCT00378014), de novo liver transplant recipients (LTxR) who switched from a calcineurin inhibitor (CNI)…
  • 2015 American Transplant Congress

    The Impact of Acute Rejection on Liver Transplant Survival in the New Millennium

    J. Levitsky,1 S. Forney,2 B. Gillespie,3 R. Merion,2,3 A. Lok,3 G. Levy,4 L. Kulik,1 M. Abecassis,1 A. Shaked.5

    1Northwestern U, Chicago, IL; 2Arbor Research Collaborative for Health, Ann Arbor, MI; 3U Michigan, Ann Arbor, MI; 4U Toronto, Toronto, ON, Canada; 5U Pennsylvania, Philadelphia, PA.

    Background: Based on pre-2000 data, acute rejection (AR) has long been considered clinically less significant in liver transplant (LT) vs. other organ recipients (Charlton et…
  • 2015 American Transplant Congress

    Rabbit Antithymocyte Globulin Is Associated With Improved Patient and Graft Survival in Liver Transplantation. Experience With 595 Patients

    M. Montenovo,1 F. Jalikis,2 L. Meng,3 Y. Matthew,2 D. Andre,1 H. Ryan,3 R. Jorge.1

    1Surgery, University of Washington, Seattle, WA; 2Pathology, University of Washington, Seattle, WA; 3Pharmacy, University of Washington, Seattle, WA.

    BACKGROUND: Use of induction therapy in liver transplantation is debatable. We aimed to compare clinical outcomes of different induction protocols in liver transplant recipients.METHODS: Retrospective…
  • 2015 American Transplant Congress

    Everolimus Initiation Immediately After Liver Transplantation: A Single-Center Experience

    U. Herden, A. Galante, S. Pischke, L. Fischer, J. Li, M. Koch, E. Achilles, B. Nashan, M. Sterneck.

    University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

    BackgroundClinical trials in liver transplant (LTX) patients with randomization on day 30 to everolimus (EVR) show a benefit in renal function compared to calcineurin inhibitor…
  • 2015 American Transplant Congress

    Bridging Therapy With Belatacept in High MELD Liver Transplant Recipients

    T. Sparkes,1 B. Masters,1 S. Hanish,2 D. Potosky,2 W. Hutson,2 J. LaMattina,2 R. Barth.2

    1University of Maryland Medical Center, Baltimore; 2University of Maryland School of Medicine, Baltimore.

    Background: Poor outcomes of high-MELD liver transplant recipients are driven by multisystem organ dysfunction. Renal failure post-transplant has been associated with mortality of greater than…
  • 2015 American Transplant Congress

    Outcomes Between ABO-Incompatible Living Donor Liver Transplantation (LDLT) and ABO-Compatible LDLT: A Matched Study

    J. Kim, S. Lee, W. Cho, J.-Y. Choi, G.-S. Choi, J. Park, C. Kwon, S. Kim, J.-W. Joh, S.-K. Lee.

    Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

    Backgrounds: Reports from several experienced centers suggested that outcomes of an ABO-incompatible (ABOi) living donor liver transplantation (LDLT) after rituximab and reduction of ABO antibodies…
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