2015 American Transplant Congress
Pre-Transplant Angiotensin Receptor II Type 1 Antibodies (AT1R) and Serum Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR) as Predictors of Post Transpalnt FSGS Recurrence
Indiana University school of Medicine-IU Health Transplant, Indianapolis, IN.
Approximately 30% of renal transplant patients develop recurrence of FSGS in the first kidney allograft. AT1R is expressed on podocytes; its expression is elevated in…2015 American Transplant Congress
Successful Management of Post Transplant Focal Segmental Glomerulosclerosis With Plasma Exchange and Rituximab
Background: Post-transplant Focal Segmental Glomerulosclerosis (FSGS) is associated with renal allograft loss. Currently, optimal treatment remains controversial. We propose a management protocol that includes treatment…2015 American Transplant Congress
Characteristics and Outcomes of Renal Transplant Recipients With Hemolytic Uremic Syndrome: An OPTN Registry Analysis
Hemolytic uremic syndrome (HUS) accounts for <1% of renal transplants in the US. There is limited data on the characteristics and outcomes of in pediatric…2015 American Transplant Congress
1-Year Safety and Efficacy of Eculizumab in Adult aHUS Patients, With or Without a History of Renal Transplant
Background: Atypical hemolytic-uremic syndrome (aHUS) is a life-threatening, chronic disease of complement-mediated TMA. In aHUS, renal transplantation is associated with post-transplant (TP) TMA and ∼50–70%…2015 American Transplant Congress
Utility of Anti-Phospholipase A2 Receptor (Anti-PLA2R) ELISA Testing in Predicting Post-Transplant Idiopathic Membranous Nephropathy (IMN)
Backgound: IMN is frequently associated with autoantibodies to the podocyte antigen, PLA2R. Anti-PLA2R associated IMN is diagnosed by detecting PLA2R antigen within glomerular immune complexes…2015 American Transplant Congress
CD3+CD4+ROR gamma t+ TH17 Cells Do Not Play a Critical Role in Islet Allograft Rejection
Medicine, The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA.
We have developed a “color-coded” adoptive transfer model for T cell subset identification that enables serial analysis of islet allograft infiltrating yellow induced regulatory T…2015 American Transplant Congress
Effective Control of Anti-Xenogeneic IL-17 Response for Tolerance Induction in Xenogeneic Islet Cell Transplantation
We have previously shown that peri-transplant infusion of donor cells treated with 1-ethyl-3-(3'-dimethylaminopropyl)-carbodiimide (ECDI) in combination with peri-transplant anti-CD20 and rapamycin induce permanent porcine islet…2015 American Transplant Congress
Pancreas-Derived Mesenchymal Stem Cells from Chronic Pancreatitis Patients Enhance Islet Graft Function
PURPOSE: Islet transplantation represents a promising procedure to reverse or prevent diabetes. However, significant mass of islet graft is lost within hours of transplantation due…2015 American Transplant Congress
A Non-Haematopoietic Erythropoietin Analogue, ARA 290, Inhibits Macrophage Activation and Prevents the Transplanted Islet Graft Damage
Purpose. Pancreatic islet transplantation (PITx) is an attractive treatment option for type 1 diabetes patients. While pancreatic islets can successfully engraft after PITx a large…2015 American Transplant Congress
Donor MHC Independent Rejection of Islet Allografts in Autoimmune NOD Mice
In autoimmune Type 1 diabetes (T1D), pancreatic islet allografts have somewhat limited long-term survival, both in T1D human subjects and in spontaneously diseased non-obese diabetic…
American Transplant Congress abstracts