2015 American Transplant Congress
Survival Benefit of Kidney Transplant Among HIV+ Waitlist Candidates
Chronic diseases, such as end-stage renal disease (ESRD), are now the leading causes of death among HIV+ patients. Multiple studies have demonstrated the efficacy of…2015 American Transplant Congress
A Gene Expression Assessment for Improving Disease Activity and Stage in Heart ABMR
Paris Transplant Group & ATAGC, Paris - Edmonton, France.
BackgroundABMR is a major cause of heart transplant failure. The diagnosis of ABMR in heart transplantation is based on the 2013 ISHLT pAMR classification. We…2015 American Transplant Congress
Designing a KDPI to Assess Live Donors and Compare Them to Deceased Donors
The Kidney Donor Profile Index (KDPI) is used to assess risk of deceased donor kidneys (DDKT) based on donor characteristics. No comparable index exists for…2015 American Transplant Congress
Erythropoietin (EPO) Has Treg Sparing Immunosuppressive Effects On Human Alloreactive T Cells
Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY.
Extending previous work showing that EPO inhibits alloreactive effector T cell proliferation by uncoupling IL2 receptor signaling (JASN 2014), we tested the effects of EPO…2015 American Transplant Congress
Immunological Characterization of Full Facial Transplant Recipients
Background: Despite the skin being considered the most immunogenic of all human tissues, full facial transplantation (FFT) has become a life transforming procedure with encouraging…2015 American Transplant Congress
Clinical and Immunological Update 15 Years After the First VCA Subsequent Kidney Transplantation After a Bilateral Hand Transplant
Background: We herein describe the long term outcome with emphasis on function, immunosuppression (IS), complication and side effects, histomorphology and graft vascular changes 15 years…2015 American Transplant Congress
Peritransplant Costimulation Blockade and Rapamycin Therapy Induces Permanent Limb Allograft Survival
Aim: Using murine models, we sought to identify the mechanisms of responsible for vascularized composite allotransplant (VCA) rejection, and to thereafter, using clinically relevant peri-transplant…2015 American Transplant Congress
Vascularized Bone Marrow Plays a Critical Role in Inducing Tolerance of Osteomyocutaneous Allografts
Background: Vascularized composite allograft (VCA) that includes medullary bone may provide proposed benefits ofvascularized bone marrow transplantation (VBMT), such as a continuous supply of donor…2015 American Transplant Congress
Concerted T-Cell Activity Against Early and Late BKV-Antigens Is Necessary for Viral Clearance
Polyomavirus-BK (BKV) associated nephropathy is a known cause of graft failure. No specific therapy is established so far and viral load monitoring accompanied by adjustment…2015 American Transplant Congress
Clinically Relevant Anti-TCR mAb Induction Plus Brief Rapamycin Therapy Can Achieve Long-Term Vascularized Composite Allograft (VCA) Survival
Aim: Current strategies for management of VCA recipients are adapted from solid organ transplant protocols, and almost universally employ induction therapy followed by maintenance triple…