2015 American Transplant Congress
Allogeneic Monocyte–Endothelial Cell Interaction Plays a Critical Role in Initiating Early Pro-Fibrosis Responses
Surgery, Duke University Medical Center, Durham, NC.
Chronic allograft nephropathy (CAN), characterized by interstitial fibrosis, vascular intimal thickening, and glomerulosclerosis, has remained as leading cause of allograft failure. The role of innate…2015 American Transplant Congress
The Forgotten Cell: Renal Fibroblasts Are Activated By Anti-MHC Class I Antibody
Medicine and Surgery, University of Alabama at Birmingham, Birmingham, AL.
Chronic antibody-mediated (CAMR) rejection remains a major obstacle in the long term survival of kidney transplants, and is associated in part with interstitial fibrosis (IF)…2015 American Transplant Congress
Cyclosporine Nephrotoxicity Is Associated With Diminished Expression of Heat Shock Protein 27 (HSP27) and Loss of Claudin-2-Dependent Intercellular Adhesion
1Medicine, University of Alabama at Birmingham, Birmingham, AL; 2INSERM U1082, Poitiers, France.
Although Cyclosporine A (CsA), a calcineurin inhibitor (CNI), is an effective immunosuppressant used to prevent kidney allograft rejection, prolonged administration is frequently associated with kidney…2015 American Transplant Congress
The Molecular Landscape of Atrophy-Fibrosis in Human Kidney Transplants: The Dominant Role of Acute Parenchymal Injury
University of Alberta, Edmonton, Canada.
We studied the effect of time post-transplant on atrophy-fibrosis (AF) and molecular associations with AF in 703 kidney transplant indication biopsies (bx) 3 days to…2015 American Transplant Congress
The Effect of Rituximab Therapy on Regulatory B Cell and Prevention of Chronic Antibody Mediated Rejection in Kidney Transplantation Recipients
Urology, Tokyo Women's Medical University, Tokyo, Japan.
We previously reported that a single administration of low dose rituximab (RIT) before kidney transplant reduced the incidence rate of chronic antibody mediated rejection (CAMR)…2015 American Transplant Congress
Referral for Kidney Transplantation in Georgia: Data from the RaDIANT Community Study
PurposeThe rate of kidney transplantation (KTx) varies significantly across US dialysis facilities. Referral for KTx from dialysis facility providers is the first key step in…2015 American Transplant Congress
Dialysis Facility Kidney Transplant Referral in Georgia: 2005-2012
Purpose: Significant variation exists in Standardized Transplantation Ratios (STR) at the dialysis facility level, and GA has the lowest kidney transplant (KTx) rate in the…2015 American Transplant Congress
Socioeconomic Determinants of Racial Disparities in Access to Preemptive Live Donor Kidney Transplantation
Racial/ethnic minorities have less access to preemptive live donor kidney transplantation (PLDKT) than whites. Our objective was to examine determinants of racial/ethnic disparities in PLDKTs…2015 American Transplant Congress
Process Deviation Tracking and Analysis in an Organ Procurement Organization
"It is common practice for Organ Procurement Organizations (OPOs) to report, collect and track issues and problems occurring during the organ donation process. We labeled…2015 American Transplant Congress
Socioeconomic Status of Local Vs Exported Liver Recipients and Their Donors
1Massachusetts General Hospital, Boston, MA; 2Mayo Clinic, Rochester, MN.
INTRODUCTION: Broader sharing has been proposed as a solution to decrease geographic disparities in liver transplantation, with the hope that this will also neutralize the…
American Transplant Congress abstracts