2015 American Transplant Congress
Donor-Derived Cell-Free DNA Is Stable in Non-Rejecting Heart Transplant Recipients in the CARGO II Multicenter Trial
1CareDx, Inc, Brisbane, CA; 2Drexel University, University of Philadelphia, Philadelphia, PA.
Purpose: An elevated fraction of donor-derived cell-free DNA (dd-cfDNA) detected in the venous blood of recipients has been shown to be correlated to rejection of…2015 American Transplant Congress
Molecular Correlates of Endothelial mTOR Activation in Heart Transplants Recipients
Paris Transplant Group & ATAGC, Paris - Edmonton, France.
BackgroundThe detection of phosphorylated effectors of the mTOR pathway in endothelial cells has been associated with in allograft rejection in animal models. The aim of…2015 American Transplant Congress
Outcome of Bortezomib/Plasmapheresis for the Sensitized Patient Awaiting Heart Transplant
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Allosensitization of patients (pts) awaiting heart transplantation is a significant challenge as it prolongs the time to transplant, increases wait-list mortality and increases risk…2015 American Transplant Congress
The Use of Eculizumab to Treat the Highly Sensitized Patient Awaiting Heart Transplant
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Highly sensitized patients (pts) awaiting heart transplantation remain a significant challenge due to prolonged often prohibitive wait times for suitable organs and increased rejection…2015 American Transplant Congress
Epidemiology and Outcomes of Non Tuberculous Mycobacterial (NTM) Infections in Solid Organ Transplant (SOT) Recipients
Infectious Diseases, Washington University School of Medicine, St. Louis, MO.
Background: NTM are uncommon causes of infection in SOT recipients but may cause significant morbidity and mortality.Methods: A retrospective cohort of all patients who underwent…2015 American Transplant Congress
Deep Surgical Site Infections (dSSI) After Liver Transplantation (LTx): Emergence of Multiple-Drug Resistant (MDR) Pathogens
Purpose: We described the epidemiology, microbiology and outcomes of dSSI after LTx.Methods: We performed a single center retrospective study of 332 consecutive patients undergoing LTX…2015 American Transplant Congress
Post-Kidney Transplant Infections in Desensitized Patients Receiving Thymoglobulin or Daclizumab Induction: Results of a Randomized Clinical Trial
Live donor kidney transplant recipients requiring desensitization for donor-specific antibody, who were enrolled in a single-center randomized trial of thymoglobulin vs. daclizumab induction, were evaluated…2015 American Transplant Congress
Epidemiology of Pneumonia in a Cohort of 5,000+ Abdominal Solid Organ Transplant Recipients
Baylor Scott & White Health, Dallas, TX.
Study purposeWe evaluated the epidemiology of pneumonia (PNE) in a longitudinal cohort of patients with abdominal (kidney, liver, and/or pancreas) solid organ transplants (SOT).MethodsRetrospective study…2015 American Transplant Congress
Efficacy of Low Dose Chemoprophylaxis for Coccidioidomycosis Infection in Liver Transplantation Recipients
Introduction:Coccidioidomycosis(CM) infection rate of 6.9% has been reported in solid organ transplantation recipients living in endemic Southwestern U.S.Aim:Assess the risk of CM infection in liver…2015 American Transplant Congress
Outcomes Associated With Carbapenem-Resistant Klebsiella Pneumoniae (CRKP) in Solid Organ Transplant (SOT) Recipients
Background: Infection with CRKP is emerging as an important challenge among SOT recipients. Our study aims to describe the epidemiology and clinical outcomes associated with…