ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    No Significant Outcome Benefit for Brand-Name Versus Generic Tacrolimus in Kidney Transplant Recipients: SRTR Analysis

    D. Goldfarb,1 E. Poggio,1 S. Flechner,1 R. Fatica,1 J. Schold.2

    1Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH; 2Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.

    IntroGeneric formulations of tacrolimus have been available for maintenance immunosuppression since 2009. Our aim was to evaluate the frequency of use of generic tacrolimus and…
  • 2015 American Transplant Congress

    Standardizing Quality Improvement Practices in Pediatric Liver Transplantation: The SPLIT A3 Project

    B. Kelly,1 R. Himes,2 J. Bucuvalas,3 L. Ware,1 S. Horslen.4

    1Surgery, Children's Hospital Pittsburgh, Pittsburgh, PA; 2Pediatrics, Texas Children's Hospital, Houston, TX; 3Pediatrics, Cincinnati Children's Hospital, Cincinnati, OH; 4Pediatrics, Seattle Children's Hospital, Seattle, WA; 5The Studies of Pediatric Liver Transplantation, EMMES Corporation, Maryland.

    Quality improvement (QI) programs are key drivers of continual reform in process and patient safety, but at present, there are no pediatric liver transplant (PLT)-specific…
  • 2015 American Transplant Congress

    Preservation Solution Impacts Short- and Long-Term Survival in Orthotopic Heart Transplant Recipients

    C. Lewis,1 S. Jayarajan,1 S. Taghavi,1 S. Kadakia,1 V. Ambur,1 A. Shiose,3 G. Wheatley,3 L. Kaiser,2 T. Guy,3 Y. Toyoda.3

    1Department of Surgery, Temple University Hospital, Philadelphia, PA; 2Division of Thoracic Surgery, Temple University Hospital, Philadelphia, PA; 3Division of Cardiovascular Surgery, Temple University Hospital, Philadelphia, PA.

    Objectives: To examine the effect of three commonly used preservation solutions on short- and long-term survival after orthotopic heart transplantation (OHT) using a large national…
  • 2015 American Transplant Congress

    The Selection Process for Total Artificial Heart

    F. Arabia, L. Czer, M. Kittleson, E. Passano, F. Liou, J. Yabuno, H. Henry, D. Chang, F. Esmailian, J. Kobashigawa, J. Moriguchi.

    Cedars-Sinai Heart Institute, Los Angeles, CA.

    Purpose: Heart failure patients with severe biventricular failure who are candidates for heart transplant are considered for Total Artificial Heart (TAH) support. These patients may…
  • 2015 American Transplant Congress

    Left Ventricular Assist Device–Associated Allosensitization — Clinical Implications

    B.-S. Ko, C. Willis, S. Drakos, D. Hurst, A. Kfoury, G. Snow, J. Delgado, E. Hammond, C. Selzman, R. Alharethi, S. McKellar, J. Nativi-Nicolau, E. Gilbert, P. Revelo, D. Miller, B. Reid, J. Fang, D. Eckles, J. Stehlik.

    U.T.A.H. Cardiac Transplant Program, Salt Lake City, UT.

    Purpose: Allosensitization has been recognized as a prognostic marker of worse outcome after transplant. It is unclear, however, whether sensitization events that take place shortly…
  • 2015 American Transplant Congress

    Examining Long-Term Survivors in Combined Heart-Lung Transplantation

    S. Kadakia,1 S. Jayarajan,1 S. Taghavi,1 V. Ambur,1 C. Lewis,1 A. Shiose,2 G. Wheatley III,2 L. Kaiser,3 T. Guy,2 Y. Toyoda.2

    1Department of Surgery, Temple University Hospital, Philadelphia, PA; 2Division of Cardiovascular Surgery, Temple University Hospital, Philadelphia, PA; 3Division of Thoracic Surgery, Temple University Hospital, Philadelphia, PA.

    The goal of this study was to determine variables associated with mortality in combined heart-lung transplantation (HLT).The United Network for Organ Sharing (UNOS) database was…
  • 2015 American Transplant Congress

    Liver Allograft Provides Immunoprotection for the Cardiac Allograft in Combined Heart-Liver Transplantation

    T. Wong, J. Stulak, J. Heimbach, M. Stegall, T. Taner.

    Mayo Clinic, Rochester, MN.

    When transplanted simultaneously, the liver allograft has been thought to have an immunoprotective role on other organs. However, detailed studies on simultaneous heart-liver transplantation (SHLT)…
  • 2015 American Transplant Congress

    Heart Transplant for Amyloid Patients in the Current Era of Bortezomib

    J. Patel, R. Vescio, M. Kittleson, S. Siddiqui, F. Liou, J. Yabuno, L. Piponniau, B. Kearney, M. Hamilton, L. Czer, J. Kobashigawa.

    Cedars-Sinai Heart Institute, Los Angeles, CA.

    Purpose: Both amyloid light chain (AL) amyloidosis and transthyretin-related (TTR) amyloid have been viewed with reluctance to proceed with heart transplant. AL amyloid in particular…
  • 2015 American Transplant Congress

    Clinically Relevant Wound Events With Everolimus-Based Immunosuppressive Regimen: Post-Hoc Analysis from a Randomized Heart Transplant Study

    A. Zuckermann,1 M. Rinaldi,1 N. Yonan,1 S.-S. Wang,1 G. Dong,2 P. Lopez.2

    1For the A2309 Study Group, Vienna, Austria; 2Novartis, Basel, Switzerland.

    Purpose: In the A2310 (NCT00300274) heart transplant (HTx) study with everolimus (EVR) vs mycophenolate mofetil (MMF), information on a broad spectrum of potential wound healing…
  • 2015 American Transplant Congress

    Antibody-Mediated Rejection of Renal Allografts by CCR5-/- Mice Does Not Require CD8 T Cells

    N. Kohei,1 T. Tanaka,1 H. Tsuda,1 N. Dvorina,1 K. Tanabe,2 W. Baldwin,1 R. Fairchild.1

    1Immunology, Cleveland Clinic, Cleveland, OH; 2Urology, Kidney Center, Tokyo Women's Medical University, Tokyo, Japan.

    Antibody-mediated acute and chronic graft injury remains a major cause of renal allograft loss. Mechanisms underlying these injuries remain unclear due in part to the…
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