ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Tacrolimus Metabolizer Heterogeneity within Caucasian Kidney Transplant (KT) Recipients

    J. Sanchez-Garcia1, N. Oliver1, D. Morris1, A. Raza1, L. Lindberg1, S. LeCorhick1, T. Srinivas2, S. Anand1

    1Intermountain Medical Center, Murray, UT, 2CareDX, South San Francisco, CA

    *Purpose: Weight-based tacrolimus (T) dosing is the standard in post-transplant KT. African-Americans and Caucasians differ in their metabolizer phenotype for T. However, two morphometrically similar…
  • 2022 American Transplant Congress

    Discordant Histological Findings During Acute Rejection in a Combined Face and Hand Transplant Recipient

    O. C. Onuh1, J. Trilles1, W. J. Rifkin1, H. Brydges1, B. F. Chaya1, R. Rodriguez Colon1, D. Boczar1, D. J. Ceradini1, E. D. Rodriguez1, B. E. Gelb2

    1Hansjörg Wyss Department of Plastic Surgery, NYU Langone Health, New York, NY, 2Transplant Institute, NYU Langone Health, New York, NY

    *Purpose: The purpose of this study is to evaluate histologic findings in a face and bilateral hand transplant recipient that was monitored with multi-site allograft…
  • 2022 American Transplant Congress

    Growing Use of Perfusion for Heart, Liver, and Lung and Early Outcomes

    R. R. Goff1, K. Gauntt1, W. Cherikh1, E. D. Lease2, D. Klassen1

    1United Network for Organ Sharing, Richmond, VA, 2University of Washington, Seattle, WA

    *Purpose: In 2015 the OPTN began collecting data on perfusion for heart, liver, and lung deceased donors (DD) on the DD registration form. Since 2015,…
  • 2022 American Transplant Congress

    HLA-DRB1 and DQB1 Amino Acid Mismatches as Determinants of Kidney Allograft Failure

    L. Gragert1, K. P. McCullough2, G. L. Wager3, R. Urbanowicz4, R. M. Merion2, M. Kamoun4

    1Tulane Cancer Center, Tulane University, New Orleans, LA, 2Arbor Research Collaborative for Health, Ann Arbor, MI, 3Tulane University, New Orleans, LA, 4University of Pennsylvania, Philadelphia, PA

    *Purpose: It was previously reported that HLA-DRB1 amino acid (AA) mismatches (MMs) at peptide-binding pockets of this molecule account for significant incremental risk of kidney…
  • 2022 American Transplant Congress

    The Impact of COVID-19 on Renal Function of Kidney Transplant Recipients: A Three-Month Prospective Study

    R. D. Foresto1, H. Fagundes2, V. Lafico2, H. Tedesco Silva Junior2, M. P. Cristelli1, J. Pestana1

    1Hospital do Rim, Sao Paulo, Brazil, 2Hospital do Rim, Universidade Federal de São Paulo, SAo Paulo, Brazil

    *Purpose: This study aimed to assess changes in renal function during the acute disease and up to three months after the onset of symptoms among…
  • 2022 American Transplant Congress

    Estimating the Effect of Increased Donor Heart Ischemic Time on Post-Transplant Survival Using Instrumental Variables

    G. Ran1, K. Lazenby1, N. Narang2, W. F. Parker3

    1Pritzker School of Medicine, University of Chicago, Chicago, IL, 2Department of Medicine, University of Illinois-Chicago, Chicago, IL, 3Department of Medicine, University of Chicago, Chicago, IL

    *Purpose: Isolate the impact of organ ischemic time on post-transplant survival using the recent change in heart allocation policy as a natural experiment.*Methods: We examined…
  • 2022 American Transplant Congress

    Type 1 Innate Lymphoid Cells Alleviate Acute Liver Injury Following Transplantation via Interferon-γ Mediated Pathway

    H. Kojima, K. Kadono, H. Hirao, K. J. Dery, J. Kupiec-Weglinski, Y. Zhai

    Dumont-UCLA Transplant Center, Los Angeles, CA

    *Purpose: Innate lymphoid cells (ILCs), a heterogeneous population of non-B non-T lymphocytes, have been found in recent years to plays key regulatory roles in tissue…
  • 2022 American Transplant Congress

    Outcomes After Covid-19 Infection in Transplant Recipients

    K. L. Freels1, K. Saharia2, J. Baddley2, N. Costa3, S. Niederhaus4

    1University of Maryland School of Medicine, Baltimore, MD, 2Medicine, University of Maryland School of Medicine, Baltimore, MD, 3Medicine, Georgetown University, Washington, DC, 4Surgery, University of Maryland School of Medicine, Baltimore, MD

    *Purpose: The purpose of this study is to evaluate outcomes of readmission, rejection, graft dysfunction, graft failure, and death in SOT recipients (SOTR) after COVID-19…
  • 2022 American Transplant Congress

    The Impact Of Covid-19 On Pediatric Organ Donation And Transplantation

    E. Lee1, X. Zhang2, G. Mazariegos3, T. Nakagawa4

    1Transplant Surgery, UPMC Childrens Hospital of Pittsburgh, Pittsburgh, PA, 2UPMC Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, 3Children's Hospital of Pittsburgh, Pittsburgh, PA, 4Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Florida College of Medicine, Jacksonville, FL

    *Purpose: The global COVID-19 pandemic has significantly altered delivery of healthcare. Hospital resource utilization has been impacted on multiple levels including solid organ transplantation and…
  • 2022 American Transplant Congress

    Ventricular Modeling Following Bariatric Surgery Decreases Need for Heart Transplantation

    R. Choudhury1, A. Rouhi2, G. Hoeltzel3, Y. Bababekov1, A. Suarez-Pierre4, A. Yule1, N. Vigneshwar4, N. Williams5, K. Dumon2, T. Nydam1

    1Transplantation Surgery, University of Colorado Hospital, Aurora, CO, 2General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, 3General Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, 4Cardiothoracic Surgery, University of Colorado Hospital, Aurora, CO, 5General Surgery, Hospital of the University of Pennsylvania, Aurora, CO

    *Purpose: For obese patients with congestive heart failure (CHF), aggressive weight loss has been associated with ventricular remodeling. Many have suggested offering bariatric surgery for…
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