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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Three‐Month Pancreas Graft Function Significantly Influences Survival Following Simultaneous Pancreas‐Kidney Transplantation in Type 1 Diabetes Patients

    M. Ji1, S. Chang1, M. Wang1, K. Lentine2, M. Merzkani1, H. Murad1, M. M. Ibrahim1, M. Zayed1, J. Wellen1, S. Sutcliffe1, T. Alhamad1

    1Washington University in St. Louis, Saint Louis, MO, 2Saint Louis University, Saint Louis, MO

    *Purpose: Simultaneous pancreas-kidney transplantation (SPK) is the only persistently successful treatment option for patients with diabetes mellitus and end-stage renal disease. However, SPK carries a…
  • 2022 American Transplant Congress

    Ventricular Modeling Following Bariatric Surgery Decreases Need for Heart Transplantation

    R. Choudhury1, A. Rouhi2, G. Hoeltzel3, Y. Bababekov1, A. Suarez-Pierre4, A. Yule1, N. Vigneshwar4, N. Williams5, K. Dumon2, T. Nydam1

    1Transplantation Surgery, University of Colorado Hospital, Aurora, CO, 2General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, 3General Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, 4Cardiothoracic Surgery, University of Colorado Hospital, Aurora, CO, 5General Surgery, Hospital of the University of Pennsylvania, Aurora, CO

    *Purpose: For obese patients with congestive heart failure (CHF), aggressive weight loss has been associated with ventricular remodeling. Many have suggested offering bariatric surgery for…
  • 2022 American Transplant Congress

    Normothermic Ex Vivo Perfusion of Discarded Human Pancreases: A Feasibility Study to Expand the Pancreas Donor Pool

    C. Parmentier, S. Ray, L. Mazilescu, M. Kawamura, Y. Noguchi, T. Goto, B. Arulratnam, S. Ganesh, M. Selzner, T. Reichman

    UHN - Toronto General Hospital, Toronto, ON, Canada

    *Purpose: Normothermic Ex Vivo Perfusion (NEVPP) model has been used in the clinical setting for Lung, heart, liver, and kidney. However, a system for human…
  • 2022 American Transplant Congress

    Fibrin Deposition in Ischemic Damaged Liver Grafts and Reconditioning with Thrombolytic Therapy During Normothermic Machine Perfusion

    T. Goto, Y. Noguchi, S. Ganesh, B. Arulratnam, M. Kawamura, C. Parmentier, S. Ray, T. Reichman, N. Selzner, M. Selzner

    Ajmera Transplant Program, Department of Surgery, Toronto General Hospital, University Health Network, Toronto, ON, Canada

    *Purpose: Normothermic ex situ perfusion (NMP) is a novel technique for the storage and assessment of marginal livers retrieved from donors after circulatory death (DCD).…
  • 2022 American Transplant Congress

    Outcomes of Post-Operative Plasmapheresis in African American Kidney Transplant Recipients with High Panel Reactive Antibodies – A Single Center Experience

    B. Valdepenas, M. Campara, J. Benken, C. Muran, D. Pierce, K. Heagler, P. DiCocco, J. Almario Alvarez, M. Spaggiari, I. Tang, I. Tzvetanov, E. Benedetti

    University of Illinois at Chicago, Chicago, IL

    *Purpose: African American (AA) kidney transplant (KTx) candidates are disadvantaged given increased immunologic risk and longer waitlist time. The purpose of this study was to…
  • 2022 American Transplant Congress

    MTOR Inhibition Acts Directly on Endothelial Cells to Induce Contact-Independent Immune-Modulation of Allo-Specific T Cell Activation

    H. Xu, L. Wang, V. A. Bendersky, Q. Gao, Q. Li, A. D. Kirk, H. Xu

    Duke University School of Medicine, Durham, NC

    *Purpose: Endothelial cells (ECs) form a barrier between vascularized organ allografts and host immunity and are known to provoke alloimmune responses. The mTOR inhibitor rapamycin…
  • 2022 American Transplant Congress

    Antibody Response to Sars- Cov -2 Mrna Vaccine in Kidney Transplant Recipients

    R. Mohamed Abdul Rahman, M. Alkadi, E. Abuhelaiqa, M. Jarman, A. Nauman, O. Fituri, M. Asim, A. Hamad, H. Tohid, P. Coyle, L. Abu Raddad, H. Al-Malki

    Nephrology, Hamad Medical Corporation, Doha, Qatar

    *Purpose: Kidney transplant recipients are vulnerable to develop severe form of COVID19 Infection. Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccine has significantly…
  • 2022 American Transplant Congress

    Organ Transplantation From Donors With Active Sars-cov-2 Infection: The Italian Experience

    P. A. Grossi1, R. Romagnoli2, S. Gruttadauria3, M. Colledan4, L. De Carlis5, S. Martin-Suarez6, G. M. Ettorre7, F. Parisi8, F. Di Benedetto9, U. Maggiore10, G. Tisone11, E. Andorno12, M. Carmellini13, L. G. Lupo14, U. Livi15, A. Montemurro16, L. Lombardini17, M. Cardillo18

    1Medicine and Surgery, Univ degli Studi dell'Insubria, 21100 Varese, Italy, 2Liver Transplant Center -General Surgery 2U, University of Turin, Torino, Italy, 3Abdominal Surgery and Organ Transplantation Unit, ISMETT, Palermo, Italy, 4Medicine and Surgery, Ospedale Papa Giovanni XXIII, 24127 Bergamo, Italy, 5CHIRURGIA GENERALE E DEI TRAPIANTI, A.O. Ospedale Niguarda Ca' Granda, 20162 Milano, Italy, 6Cardio Thoracic and Vascular Department, University of Bologna S.Orsola - Malpighi, 40138 Bologna, Italy, 7Dipartimento Interaziendale Trapianti Silvio Natoli, A.O. San Camillo - Forlanini, 00149 Roma, Italy, 8DIPARTIMENTO CARDIOCHIRURGIA CARDIOLOGIA E TRAPIANTO CUORE POLMONE, Ospedale Bambino Gesù, 00165 Roma, Italy, 9Medicine and Surgery, AOU Policlinico, 41124 Modena, Italy, 10Dipartimento di Medicina Generale e Specialistica, Ospedale Maggiore - Parma, 21100 Varese, Italy, 11Chirurgia Generale, A.O.U. Policlinico Tor Vergata, 00133 Roma, Italy, 12Dipartimento di Chirurgia, Ospedale Policlinico San Martino, 16132 Genova, Italy, 13Dipartimento di Scienze Mediche, Chirurgiche e Neuroscienze, A.O.U. Senese - S.M. Alle Scotte, 53100 Siena, Italy, 14E’mergenza e trapianti di organi, AOU Consorziale Policlinico, 70124 Bari, Italy, 15Medicine and Surgery, Azienda Sanitaria Universitaria Integrata di Udine, 33100 Udine, Italy, 16Centro Nazionale Trapianti Operativo, CNT, 00162 Roma, Italy, 17Medical DirectOR, CNT, 00162 Roma, Italy, 18General Director, CNT, 00162 Roma, Italy

    *Purpose: In the present study we want to report safety and outcome of organ transplantation from donors with active SARS-CoV-2 infection in Italy.*Methods: In November…
  • 2022 American Transplant Congress

    Experience with Covid-19 Infection and Vaccination in Combined Kidney/HSCT Recipients

    M. Gibson1, D. Belshe1, G. Gregory1, S. Tanna1, M. Ison1, S. Ildstad2, J. R. Leventhal1

    1Northwestern University, Chicago, IL, 2University of Louisville, Louisville, KY

    *Purpose: Kidney transplant(KTx) recipients are at increased risk of COVID-19 related complications. KTx pts who have undergone therapy to induce tolerance are a unique cohort…
  • 2022 American Transplant Congress

    Comparing Infection Rate Between Steroid Withdrawal and Ongoing Maintenance Among Simultaneous Pancreas-Kidney Transplant Recipients

    M. McCord1, Z. Yetmar2, A. Lemke1, K. Mara3, M. T. Seville4, W. Bosch5, P. Dean6, E. Beam2, S. Bernard1

    1Department of Pharmacy, Mayo Clinic, Rochester, MN, 2Division of Infectious Diseases, Mayo Clinic, Rochester, MN, 3Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 4Division of Infectious Diseases, Mayo Clinic Arizona, Scottsdale, AZ, 5Division of Infectious Diseases, Mayo Clinic, Jacksonville, FL, 6Division of Transplantation Surgery, Mayo Clinic, Rochester, MN

    *Purpose: Compare infection rates of simultaneous pancreas-kidney transplant (SPK) recipients who continue maintenance steroids to those with steroid withdrawal post transplant.*Methods: This study is a…
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