ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Vaccination to Prevent the High Herpes Zoster Incidence After Renal Transplantation

    M. Kho,1 W. Weimar,1 D. Boveé,1 M. Boer-Verschragen,1 A. van der Eijk,2 N. van Besouw.1

    1Internal Medicine - Nephrology and Transplantation, Erasmus Medical Center, Rotterdam, Netherlands; 2Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.

    Introduction: Herpes zoster (HZ) is the clinical manifestation of varicella zoster virus (VZV) reactivation and occurs more frequently in people with a suppressed immune system.…
  • 2015 American Transplant Congress

    The Effect of Influenza Vaccination on Hospital Admission in Solid Organ Transplant Recipients

    J. Rago, M. Hurtik, S. Todd, A. Mehta, G. Lyon III.

    Emory University Hospital, Atlanta, GA.

    Purpose: The current study has two objectives. First, compare clinical outcomes between solid organ transplant (SOT) recipients who receive influenza vaccination and those who do…
  • 2015 American Transplant Congress

    Variables Related to the Development of Donor Specific Antibodies (DSA) Post-Kidney Transplant (KTx): Implications for Late Graft Histology and Survival

    F. Cosio,1 C. Schinstock,1 M. Stegall.2

    1Medicine, Mayo Clinic, Rochester, MN; 2Surgery, Mayo Clinic, Rochester, MN.

    Introduction. The incidence of de novo DSA increases post-KTx. DSA is associated to reduced graft survival likely due to chronic antibody mediated rejection (cAMR). However,…
  • 2015 American Transplant Congress

    HLA-Cw Mismatches Are Not Associated With Worse Graft Outcomes After Kidney Transplantation Even in High Levels of Antigen Expression

    M. Askar,1 N. Elfadawy,1,2 S. Flechner,1 K. Abu-Elmagd,1 J. Fung,1 J. Schold.1

    1Cleveland Clinic, Cleveland; 2University of Alexandria, Alexandria, Egypt.

    The HLA-Cw antigens are distinct in having relatively lower expression on the cell surface compared to the other HLA class I loci. Higher HLA Cw…
  • 2015 American Transplant Congress

    Furthering the Link Between Ischemia and Immunity: Development of New Antibody Following Prolonged Delayed Graft Function

    A. Gilbert,1 E. Hall,1 O. Timofeeva,2 M. Awwad,2 M. Grafals,1 P. Weems,1 D. Li,2 S. Rosen-Bronson,2 J. Moore,1 B. Javaid,1 M. Cooper.1

    1Department of Surgery, MedStar Georgetown Transplant Institute, Washington, DC; 2Department of Pathology, MedStar Georgetown Transplant Institute, Washington, DC.

    Introduction The purpose of this study is to examine the relationship between prolonged ischemia (delayed graft function - DGF) and the development of de novo…
  • 2015 American Transplant Congress

    Donor-Specific Alloantibody After Positive Crossmatch Kidney Transplantation With Eculizumab (EC): Correlation With Transplant Glomerulopathy and Graft Failure

    C. Schinstock,1 F. Cosio,1 L. Cornell,1 M. Gandhi,1 M. Everly,2 M. Stegall.1

    1Mayo Clinic, Rochester, MN; 2Paul Terasaki Foundation, Los Angeles, CA.

    Introduction. EC (C5 blockade) reduces the incidence of early clinical acute antibody mediated rejection (AMR) after +XMKTx, but does not prevent chronic AMR. We examined…
  • 2015 American Transplant Congress

    Is Electron Microscopy Adding a Diagnostic Advantage in the Evaluation of Renal Allograft Biopsies for Antibody Mediated Rejection (AMR)?

    J. Papadimitriou, M. Chaudhry, C. Drachenberg, R. Ugarte, D. Klassen, E. Ramos, C. Cangro, B. Thomas, M. Mavanur, A. Haririan.

    Pathology and Medicine, University of Maryland School of Medicine, Baltimore, MD.

    Some electron microscopy (EM) findings have been consistently associated with antibody mediated microvascular injury; however, no large studies have been performed examining the concrete advantage…
  • 2015 American Transplant Congress

    Clinical Subclassifiation of ABMR Phenotypes: Recognizing Variation in Presentation

    P. Halloran, M. Lopez, I. Salazar, J. Chang.

    Alberta Transplant Applied Genomics Centre, Edmonton, Canada.

    The diagnosis of ABMR in kidney transplants is based on ptc-, g- and cg-lesions in biopsies and donor-specific antibody (DSA). To recognize the actual phenotypes…
  • 2015 American Transplant Congress

    Histology and Not Donor Specific Antibody Helps Predict 5-Year Kidney Transplant Failure Using 1 Year Post-Transplant Data

    M. Moreno Gonzales,1 A. Bentall,2,3 M. Stegall,1 R. Borrows.2

    1Department of Transplant Surgery, Mayo Clinic, Rochester, MN; 2Department of Nephrology, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom; 3School of Immunity and Infection, University of Birmingham, Birmingham, United Kingdom.

    Introduction: The objective of this study was to validate the RISK score (Am J Kid D 2014; 63[4]:643) for renal allograft failure using a different…
  • 2015 American Transplant Congress

    Early Clinical Indicators of Long Term Survival and Allograft Loss Following De Novo DSA. A 15-Year Longitudinal Study

    M. Everly,1 L. Rebellato,2 K. Briley,2 A. Maldonado,3 P. Bolin,2 C. Haisch,2 W. Kendrick,4 S. Kendrick,4 C. Morgan,2 R. Harland,2 P. Terasaki.1

    1Terasaki Foundation, Los Angeles, CA; 2East Carolina University, Greenville, NC; 3Vidant Medical Center, Greenville, NC; 4Eastern Nephrology Associates, Greenville, NC.

    Improvement in outcomes in renal transplant patients with de novo donor specific anti-HLA antibodies (dnDSA) is needed. This analysis aims to identify surrogate endpoints following…
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